Search Results - "Shicai Fan"
-
1
MRCNN: a deep learning model for regression of genome-wide DNA methylation
Published in BMC genomics (04-04-2019)“…Determination of genome-wide DNA methylation is significant for both basic research and drug development. As a key epigenetic modification, this biochemical…”
Get full text
Journal Article -
2
Joint-specific DNA methylation and transcriptome signatures in rheumatoid arthritis identify distinct pathogenic processes
Published in Nature communications (10-06-2016)“…Stratifying patients on the basis of molecular signatures could facilitate development of therapeutics that target pathways specific to a particular disease or…”
Get full text
Journal Article -
3
A new technique for percutaneous screw fixation for treating FFP IIIa and IIIb fragility fractures of the pelvis
Published in Scientific reports (30-07-2024)“…To determine the presence of a consistent osseous corridor from the lateral-posterior aspect of the anterior inferior iliac spine to the sacral wing that could…”
Get full text
Journal Article -
4
ROS-Eliminating Carboxymethyl Chitosan Hydrogel to Enhance Burn Wound-Healing Efficacy
Published in Frontiers in pharmacology (14-06-2021)“…Overexpression of reactive oxygen species (ROS) can lead to chronic inflammation, which limits skin wound healing. Therefore, it is of great significance to…”
Get full text
Journal Article -
5
Customized a Ti6Al4V Bone Plate for Complex Pelvic Fracture by Selective Laser Melting
Published in Materials (04-01-2017)“…In pelvic fracture operations, bone plate shaping is challenging and the operation time is long. To address this issue, a customized bone plate was designed…”
Get full text
Journal Article -
6
PretiMeth: precise prediction models for DNA methylation based on single methylation mark
Published in BMC genomics (15-05-2020)“…The computational prediction of methylation levels at single CpG resolution is promising to explore the methylation levels of CpGs uncovered by existing array…”
Get full text
Journal Article -
7
Three-dimensional printing of patient-specific plates for the treatment of acetabular fractures involving quadrilateral plate disruption
Published in BMC musculoskeletal disorders (10-07-2020)“…Complicated acetabular fractures comprise the most challenging field for orthopedists. The purpose of this study was to develop three-dimensional printed…”
Get full text
Journal Article -
8
A robust fuzzy rule based integrative feature selection strategy for gene expression data in TCGA
Published in BMC medical genomics (31-01-2019)“…Lots of researches have been conducted in the selection of gene signatures that could distinguish the cancer patients from the normal. However, it is still an…”
Get full text
Journal Article -
9
Cryogenic 3D printing of bifunctional silicate nanoclay incorporated scaffolds for promoted angiogenesis and bone regeneration
Published in Materials & design (01-11-2022)“…[Display omitted] •Silicate nanoclay incorporated β-tricalcium phosphate/poly(lactide-coglycolide) composites with hierarchical structure were fabricated via…”
Get full text
Journal Article -
10
MicroRNA-26a inhibits osteosarcoma cell proliferation by targeting IGF-1
Published in Bone research (22-12-2015)“…There are still controversies about the roles of microRNA-26a(miR-26a)in human malignancies,as it is a tumor suppressor in breast cancer,gastric cancer,and…”
Get full text
Journal Article -
11
Biomechanical study of Tile C3 pelvic fracture fixation using an anterior internal system combined with sacroiliac screws
Published in Journal of orthopaedic surgery and research (27-03-2021)“…How to perform minimally-invasive surgery on Tile C pelvic fractures is very difficult, and it is also a hot topic in orthopedic trauma research. We applied…”
Get full text
Journal Article -
12
The application of lateral-rectus approach on toddlers' unstable pelvic fractures
Published in BMC musculoskeletal disorders (04-03-2020)“…Pelvic fractures are rare in toddlers but are often associated with other injuries that make treatment difficult. Conservative treatment has been used with…”
Get full text
Journal Article -
13
Clinical application of anterior ring internal fixator system combined with sacroiliac screw fixation in Tile C pelvic fracture treatment
Published in Journal of orthopaedic surgery and research (14-12-2021)“…How to perform minimally invasive surgery for Tile C pelvic fracture is a major problem in clinical practice. We performed minimally invasive surgery for Tile…”
Get full text
Journal Article -
14
Identification of safe channels for screws in the anterior pelvic ring fixation system
Published in Journal of orthopaedic surgery and research (11-06-2022)“…Minimally invasive surgery for pelvic fracture using anterior ring internal fixator system is increasing gradually, and the way to insert the fixation screws…”
Get full text
Journal Article -
15
Internal fixation of acetabular fractures in an older population using the lateral-rectus approach: short-term outcomes of a retrospective study
Published in Journal of orthopaedic surgery and research (04-01-2019)“…This study aims to examine the clinical efficacy and surgical techniques of the lateral-rectus approach for treatment of acetabular factures in elderly…”
Get full text
Journal Article -
16
Central dislocation of femoral head without involvement of acetabular anterior and posterior columns
Published in Journal of international medical research (01-08-2018)“…Objective This study was performed to explore the treatment of central dislocation of the femoral head without involvement of the acetabular columns. Methods…”
Get full text
Journal Article -
17
Effect of different lumbar–iliac fixation and sacral slope for Tile C1.3 pelvic fractures: a biomechanical study
Published in Journal of orthopaedics and traumatology (26-06-2024)“…Background Lumbar–iliac fixation (LIF) is a common treatment for Tile C1.3 pelvic fractures, but different techniques, including L4–L5/L5 unilateral LIF…”
Get full text
Journal Article -
18
Design and Application of an Acetabular Integrative Anatomic Plate: A Retrospective Study of 178 Cases with Complex Acetabular Fractures
Published in Orthopaedic surgery (01-10-2023)“…Objective As conventional plates require repeated pre‐bending during surgery with poor matching, this study aimed to explore the design and application of an…”
Get full text
Journal Article -
19
Integrative analysis with expanded DNA methylation data reveals common key regulators and pathways in cancers
Published in Npj genomic medicine (01-02-2019)“…The integration of genomic and DNA methylation data has been demonstrated as a powerful strategy in understanding cancer mechanisms and identifying therapeutic…”
Get full text
Journal Article -
20
scMelody: An Enhanced Consensus-Based Clustering Model for Single-Cell Methylation Data by Reconstructing Cell-to-Cell Similarity
Published in Frontiers in bioengineering and biotechnology (23-02-2022)“…Single-cell DNA methylation sequencing technology has brought new perspectives to investigate epigenetic heterogeneity, supporting a need for computational…”
Get full text
Journal Article