Search Results - "Shibuya, Isao"

Antibacterial and Immunosuppressive Effects of OPS-2071, a Candidate Therapy for Inflammatory Bowel Disease by Sato, Masayoshi, Fujii, Kazuyuki, Takagi, Hiroko, Shibuya, Isao, Oka, Daisuke, Yamaya, Naomitsu, Hagita, Hiraku, Matsumoto, Makoto, Inagaki, Katsuya

“…Background Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract. Although many types of drug are used, clinical…”
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Cardiac neural crest cells contribute to the dormant multipotent stem cell in the mammalian heart by Tomita, Yuichi, Matsumura, Keisuke, Wakamatsu, Yoshio, Matsuzaki, Yumi, Shibuya, Isao, Kawaguchi, Haruko, Ieda, Masaki, Kanakubo, Sachiko, Shimazaki, Takuya, Ogawa, Satoshi, Osumi, Noriko, Okano, Hideyuki, Fukuda, Keiichi

“…Arodent cardiac side population cell fraction formed clonal spheroids in serum-free medium, which expressed nestin, Musashi-1, and multi-drug resistance…”
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Accumulation of HLA-DR4 in Colonic Epithelial Cells Causes Severe Colitis in Homozygous HLA-DR4 Transgenic Mice by Irie, Atsushi, Imamura, Takahisa, Michibata, Yayoi, Kubo, Ttatsuko, Takeda, Naoki, Shibuya, Isao, Sogo, Shinji, Araki, Kimi, Nishimura, Yasuharu

“…Homozygous HLA-DR4/I-E transgenic mice (tgm) spontaneously developed colitis similar to human ulcerative colitis. We explored whether endoplasmic reticulum…”
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Establishment of HLA-DR4 transgenic mice for the identification of CD4+ T cell epitopes of tumor-associated antigens by Yatsuda, Junji, Irie, Atsushi, Harada, Kumiko, Michibata, Yayoi, Tsukamoto, Hirotake, Senju, Satoru, Tomita, Yusuke, Yuno, Akira, Hirayama, Masatoshi, Abu Sayem, Mohammad, Takeda, Naoki, Shibuya, Isao, Sogo, Shinji, Fujiki, Fumihiro, Sugiyama, Haruo, Eto, Masatoshi, Nishimura, Yasuharu

“…Reports have shown that activation of tumor-specific CD4(+) helper T (Th) cells is crucial for effective anti-tumor immunity and identification of Th-cell…”
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Painful lumbar spondylolysis among pediatric sports players: a pilot MRI study by Sairyo, Koichi, Sakai, Toshinori, Mase, Yasuyoshi, Kon, Tamiyo, Shibuya, Isao, Kanamori, Yasuo, Kosugi, Tatsuo, Dezawa, Akira

“…Introduction For children and adolescents who are very active athletes, fresh lumbar spondylolysis is the main pathologic cause of lower back pain (LBP)…”
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Solitary synovial chondromatosis arising in the gluteus maximus bursa: computed tomography and magnetic resonance imaging findings by Sumida, Kaoru, Kobayashi, Noriko, Nambu, Atsushi, Tago, Masao, Shibuya, Isao, Kawamoto, Masashi

“…Chondral tumors in soft tissue are referred to as soft-tissue chondromas or extraskeletal chondromas, or as synovial chondromatosis if they arise in synovial…”
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Development of dual-curing type experimental composite resin cement for orthodontic bonding –Effect of additional amount of accelerators on the mechanical properties by LI, Jun, SHIBUYA, Isao, TESHIMA, Ichiko, NEMOTO, Kimiya, NISHIYAMA, Norihiro

“…In this study, a dual-curing type composite resin cement that included a photo-initiator and two accelerators was designed. In particular, special emphasis was…”
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Four-Rod Stabilization of Severely Destabilized Lumbar Spine Caused by Metastatic Tumor by Sairyo, Koichi, Dezawa, Akira, Shibuya, Isao, Kanamori, Yasuo

“…We report a case of a 67-year-old female with severely destabilized lumbar spine caused by metastatic malignant tumor. The primary lesion was a thyroid…”
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V-rod technique for direct repair surgery of pediatric lumbar spondylolysis combined with posterior apophyseal ring fracture by Sumita, Takayuki, Sairyo, Koichi, Shibuya, Isao, Kitahama, Yoshihiro, Kanamori, Yasuo, Matsumoto, Hironori, Koga, Soichi, Kitagawa, Yasuhiro, Dezawa, Akira

“…We report a pediatric baseball player having both a fracture of the posterior ring apophysis and spondylolysis. He was presented to a primary care physician…”
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Multilevel Direct Repair Surgery for Three-Level Lumbar Spondylolysis by Arai, Tetsu, Sairyo, Koichi, Shibuya, Isao, Kato, Ko, Dezawa, Akira

“…A 45-year-old man presented to our clinic requesting evaluation for surgical treatment of chronic low back pain of more than 20 years duration. He was…”
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Lumbar Spondylolysis in Juveniles from the Same Family : A Report of Three Cases and a Review of the Literature by Yamada, Atsuhisa, Sairyo, Koichi, Shibuya, Isao, Kato, Ko, Dezawa, Akira, Sakai, Toshinori

“…Spondylolysis is reported as a stress fracture of the pars interarticularis with a strong hereditary basis. Three cases of lumbar spondylolysis in juveniles…”
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Brace management for huge bone defect after malignant pelvic bone tumor excision by Shibuya, Isao, Yoshimoto, Yukiko, Miki, Hiroshi, Dezawa, Kira

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Development of dual-curing type experimental composite resin cement for orthodontic bonding - Effect of additional amount of accelerators on the mechanical properties by Jun LI, Isao SHIBUYA, Ichiko TESHIMA, Kimiya NEMOTO, Norihiro NISHIYAMA

“…In this study, a dual-curing type composite resin cement that included a photo-initiator and two accelerators was designed. In particular, special emphasis was…”
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Active increase in cardiolipin synthesis in the stationary growth phase and its physiological significance in Escherichia coli by Hiraoka, Shuichi, Matsuzaki, Hiroshi, Shibuya, Isao

“…Activity of the Escherichia coli cardiolipin synthase, encoded by cls, increased about 10-fold in the stationary growth phase, while other committedstep…”
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Novel and Efficient Synthesis of 4-Dimethylamino-2-glycosylaminoquinazolines by Cyclodesulfurization of Glycosyl Thioureas with Dimethylcyanamide by Gama, Yasuo, Shibuya, Isao, Shimizu, Masao

“…4-Dimethylamino-2-glycosylaminoquinazoline derivatives were synthesized by cyclodesulfurization of N-aryl-N′-glycosyl thioureas with dimethylcyanamide in the…”
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Surgical treatment of a lumbar aneurysmal bone cyst using percutaneous endoscopic lumbar discectomy by Shibuya, Isao, Dezawa, Akira, Urayama, Shigeki, Nakamura, Shigeru

“…Purpose Aneurysmal bone cysts of the lumbar spine are usually treated by curettage followed by bone or bioactive ceramics grafting. Here, we present the first…”
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Design of a temporally and spatially controlled drug delivery system for the treatment of liver diseases in mice by Shibuya, Isao, Akaike, Toshihiro, Watanabe, Yoshifumi

“…Strict regulation of the distribution and degradation kinetics is the ultimate aim of drug delivery system. Regulation of drug delivery would increase the…”
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Mo1094 OPS-2071 HEALS T CELL MEDIATED COLITIS, MURINE CROHN'S DISEASE MODEL, WITH ANTI-INFLAMMATORY AND ANTI-BACTERIAL ACTIVITY by Takagi, Hiroko, Sato, Masayoshi, Fujii, Kazuyuki, Shibuya, Isao, Oka, Daisuke, Yamaya, Naomitsu, Inagaki, Katsuya

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P155 THERAPEUTIC EFFECT OF OPS-2071 ON HEALING OF T CELL-MEDIATED COLITIS, A MURINE MODEL OF CROHN’S DISEASE, WITH ANTI-INFLAMMATORY AND ANTIBACTERIAL ACTIVITY by Takagi, Hiroko, Sato, Masayoshi, Fujii, Kazuyuki, Shibuya, Isao, Oka, Daisuke, Yamaya, Naomitsu, Inagaki, Katsuya

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Synthesis of 1,2-Benzisothiazolin-3-one by Transamination of Sulfenamides by Shimizu, Masao, Takeda, Ayanobu, Fukazawa, Hidenori, Abe, Yoshimoto, Shibuya, Isao

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