Search Results - "Shibusawa, N."

Transient expression of thyroid hormone nuclear receptor TR beta 2 sets S opsin patterning during cone photoreceptor genesis by Applebury, M L, Farhangfar, F, Glosmann, M, Hashimoto, K, Kage, K, Robbins, J T, Shibusawa, N, Wondisford, F E, Zhang, H

“…Cone photoreceptors in the murine retina are patterned by dorsal repression and ventral activation of S opsin. TR2, the nuclear thyroid hormone receptor…”
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Aberrant Dynamics of Histone Deacetylation at the Thyrotropin-Releasing Hormone Gene in Resistance to Thyroid Hormone by Ishii, S, Yamada, M, Satoh, T, Monden, T, Hashimoto, K, Shibusawa, N, Onigata, K, Morikawa, A, Mori, M

“…Histone acetylation status influences transcriptional activity, and the mechanism of negative gene regulation by thyroid hormone remains unclear, although its…”
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Transient expression of thyroid hormone nuclear receptor TRβ2 sets S opsin patterning during cone photoreceptor genesis by Applebury, M.L., Farhangfar, F., Glösmann, M., Hashimoto, K., Kage, K., Robbins, J.T., Shibusawa, N., Wondisford, F.E., Zhang, H.

“…Cone photoreceptors in the murine retina are patterned by dorsal repression and ventral activation of S opsin. TRβ2, the nuclear thyroid hormone receptor β…”
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Thyroid Hormone Receptor DNA Binding Is Required for Both Positive and Negative Gene Regulation by Shibusawa, Nobuyuki, Hollenberg, Anthony N., Wondisford, Fredric E.

“…The β isoform of thyroid hormone receptor (TR-β) has a key role in the feedback regulation of the hypothalamic-pituitary-thyroid (H-P-T) axis. The mechanism of…”
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Insulin regulation of hepatic gluconeogenesis through phosphorylation of CREB-binding protein by Wondisford, Fredric E, Zhou, Xiao Yan, Shibusawa, Nobuyuki, Naik, Karuna, Porras, Delia, Temple, Karla, Ou, Hesheng, Kaihara, Kelly, Roe, Michael W, Brady, Matthew J

“…Hepatic gluconeogenesis is essential for maintenance of normal blood glucose concentrations and is regulated by opposing stimulatory (cyclic adenosine…”
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Dominant Role of Thyrotropin-releasing Hormone in the Hypothalamic-Pituitary-Thyroid Axis by Nikrodhanond, Amisra A., Ortiga-Carvalho, Tania M., Shibusawa, Nobuyuki, Hashimoto, Koshi, Liao, Xiao Hui, Refetoff, Samuel, Yamada, Masanobu, Mori, Masatomo, Wondisford, Fredric E.

“…Hypothalamic thyrotropin-releasing hormone (TRH) stimulates thyroid-stimulating hormone (TSH) secretion from the anterior pituitary. TSH then initiates thyroid…”
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Thyroid hormone action in the absence of thyroid hormone receptor DNA-binding in vivo by Shibusawa, N, Hashimoto, K, Nikrodhanond, A A, Liberman, M C, Applebury, M L, Liao, X H, Robbins, J T, Refetoff, S, Cohen, R N, Wondisford, F E

“…Thyroid hormone action is mediated by thyroid hormone receptors (TRs), which are members of the nuclear hormone receptor superfamily. DNA-binding is presumed…”
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Negative regulation by thyroid hormone receptor requires an intact coactivator-binding surface by Ortiga-Carvalho, Tania M, Shibusawa, Nobuyuki, Nikrodhanond, Amisra, Oliveira, Karen J, Machado, Danielle S, Liao, Xiao-Hui, Cohen, Ronald N, Refetoff, Samuel, Wondisford, Fredric E

“…Thyroid hormone (TH) action is mediated by TH receptors (TRs), which are members of the nuclear hormone receptor superfamily. In vitro studies have…”
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Prolactin Secretion in Mice with Thyrotropin-Releasing Hormone Deficiency by Yamada, Masanobu, Shibusawa, Nobuyuki, Ishii, Sumiyasu, Horiguchi, Kazuhiko, Umezawa, Ryohei, Hashimoto, Koshi, Monden, Tsuyoshi, Satoh, Teturo, Hirato, Junko, Mori, Masatomo

“…The physiological roles of TRH in pituitary lactotrophs, particularly during lactation, remain unclear. We studied the prolactin (PRL) status, including serum…”
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Roles of proteasomal 19S regulatory particles in promoter loading of thyroid hormone receptor by Satoh, Tetsurou, Ishizuka, Takahiro, Yoshino, Satoshi, Tomaru, Takuya, Nakajima, Yasuyo, Shibusawa, Nobuyuki, Hashimoto, Koshi, Yamada, Masanobu, Mori, Masatomo

“…19S regulatory particles (19SRP) of 26S proteasome participate in multiple steps of gene transcription in yeast. We previously showed that Tat-binding…”
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Tertiary Hypothyroidism and Hyperglycemia in Mice with Targeted Disruption of the Thyrotropin-Releasing Hormone Gene by Yamada, Masanobu, Saga, Yumiko, Shibusawa, Nobuyuki, Hirato, Jyunko, Murakami, Masami, Iwasaki, Toshiharu, Hashimoto, Koshi, Satoh, Teturou, Wakabayashi, Katsumi, Taketo, Makoto M., Mori, Masatomo

“…Thyrotropin-releasing hormone (TRH) is a brain hypothalamic hormone that regulates thyrotropin (TSH) secretion from the anterior pituitary and is ubiquitously…”
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Requirement of thyrotropin-releasing hormone for the postnatal functions of pituitary thyrotrophs: ontogeny study of congenital tertiary hypothyroidism in mice by Shibusawa, N, Yamada, M, Hirato, J, Monden, T, Satoh, T, Mori, M

“…We recently reported that TRH-deficient mice showed characteristic tertiary hypothyroidism. In the present study, we investigated how this tertiary…”
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Human immunodeficiency virus type 1 Tat binding protein-1 is a transcriptional coactivator specific for TR by Ishizuka, T, Satoh, T, Monden, T, Shibusawa, N, Hashida, T, Yamada, M, Mori, M

“…The DNA-binding domain of nuclear hormone receptors functions as an interaction interface for other transcription factors. Using the DNA-binding domain of…”
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Transient expression of thyroid hormone nuclear receptor TRbeta2 sets S opsin patterning during cone photoreceptor genesis by Applebury, M L, Farhangfar, F, Glösmann, M, Hashimoto, K, Kage, K, Robbins, J T, Shibusawa, N, Wondisford, F E, Zhang, H

“…Cone photoreceptors in the murine retina are patterned by dorsal repression and ventral activation of S opsin. TR beta 2, the nuclear thyroid hormone receptor…”
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Unliganded RXR acts as an inhibitory factor on troglitazone-induced activation by Monden, Tsuyoshi, Yamada, Masanobu, Nihei, Yasuyo, Kishi, Mikiko, Tomaru, Takuya, Ishii, Sumiyasu, Hashida, Tetsu, Shibusawa, Nobuyuki, Hashimoto, Koshi, Satoh, Teturou, Kasai, Kikuo, Mori, Masatomo

“…Troglitazone (TZ), a thiazolidinedione derivative, is a specific ligand for the peroxisome proliferator-activated receptor (PPAR) γ and improves insulin…”
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Regulation of the mouse preprothyrotropin-releasing hormone gene by retinoic acid receptor by Satoh, T, Ishizuka, T, Monden, T, Shibusawa, N, Hashida, T, Kishi, M, Yamada, M, Mori, M

“…Retinoic acid (RA) has been reported to inhibit the secretion and synthesis of the pituitary TSH in vivo and in vitro. However, little is known about the…”
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Expression of Thyrotropin-Releasing Hormone (TRH) receptor subtype 1 in mouse pancreatic islets and HIT-T15, an insulin-secreting clonal β cell line by Yamada, Masanobu, Shibusawa, Nobuyuki, Hashida, Tetsu, Ozawa, Atsushi, Monden, Tsuyoshi, Satoh, Teturou, Mori, Masatomo

“…Thyrotropin-releasing hormone (TRH), originally isolated as a hypothalamic hormone, has been reported to be present and released from the pancreatic β cells,…”
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Isolation and Characterization of the Rat Prolactin-Releasing Peptide Gene: Multiple TATA Boxes in the Promoter Region by Yamada, Masanobu, Ozawa, Atsushi, Ishii, Sumiyasu, Shibusawa, Nobuyuki, Hashida, Tetsu, Ishizuka, Takahiro, Hosoya, Takeshi, Monden, Tsuyoshi, Satoh, Teturou, Mori, Masatomo

“…The prolactin-releasing peptide (PrRP) gene is a novel bioactive peptide expressed in very restricted regions in the brain. To explore the molecular mechanism…”
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A novel transcript for the thyrotropin-releasing hormone receptor in human pituitary and pituitary tumors by YAMADA, M, HASHIMOTO, K, SATOH, T, SHIBUSAWA, N, KOHGA, H, OZAWA, Y, YAMADA, S, MORI, M

“…We measured the amounts of TRH receptor (TRHR) messenger ribonucleic acid (mRNA) in human normal pituitary and pituitary tumors and found a novel transcript of…”
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Genomic organization and promoter function of the mouse uncoupling protein 2 (UCP2) gene by Yamada, Masanobu, Hashida, Tetsu, Shibusawa, Nobuyuki, Iwasaki, Toshiharu, Murakami, Masami, Monden, Tsuyoshi, Satoh, Teturou, Mori, Masatomo

“…We cloned and characterized the mouse uncoupling protein 2 (UCP2) gene and its promoter region. The gene spans approximately 6.3 kb and contains eight exons…”
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