Search Results - "Shibata, Erwin F."

A computational investigation of cardiac caveolae as a source of persistent sodium current by Besse, Ian M, Mitchell, Colleen C, Hund, Thomas J, Shibata, Erwin F

“…Recent studies of cholesterol-rich membrane microdomains, called caveolae, reveal that caveolae are reservoirs of "recruitable" sodium ion channels. Caveolar…”
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Effects of epoxyeicosatrienoic acids on the cardiac sodium channels in isolated rat ventricular myocytes by Lee, Hon‐Chi, Lu, Tong, Weintraub, Neal L., VanRollins, Mike, Spector, Arthur A., Shibata, Erwin F.

“…Whole-cell Na + currents (holding potential, −80 mV; test potential, −30 mV) in rat myocytes were inhibited by 8,9-epoxyeicosatrienoic acid (8,9-EET) in a…”
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Molecular determinants of intracellular pH modulation of human Kv1.4 N-type inactivation by Padanilam, Benzy J, Lu, Tong, Hoshi, Toshinori, Padanilam, Beena A, Shibata, Erwin F, Lee, Hon-Chi

“…A-type K+ currents serve important functions in neural and cardiac physiology. The human A-type Kv1.4 channel (hKv1.4) shows fast N-type inactivation when…”
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Localization of Cardiac Sodium Channels in Caveolin-Rich Membrane Domains: Regulation of Sodium Current Amplitude by Yarbrough, Tracy L, Lu, Tong, Lee, Hon-Chi, Shibata, Erwin F

“…This study demonstrates that caveolae, omega-shaped membrane invaginations, are involved in cardiac sodium channel regulation by a mechanism involving the α…”
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Autonomic Regulation of Voltage-Gated Cardiac Ion Channels by SHIBATA, ERWIN F., BROWN, TRACY L.Y., WASHBURN, ZACHARY W., BAI, JING, REVAK, THOMAS J., BUTTERS, CAROL A.

“…Altering voltage‐gated ion channel currents, by changing channel number or voltage‐dependent kinetics, regulates the propagation of action potentials along the…”
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Modulation of rat cardiac sodium channel by the stimulatory G protein α subunit by Lu, Tong, Lee, Hon‐Chi, Kabat, Julia A., Shibata, Erwin F.

“…1 Modulation of cardiac sodium currents (INa) by the G protein stimulatory α subunit (Gsα) was studied using patch‐clamp techniques on freshly dissociated rat…”
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Dihydropyridine action on voltage-dependent potassium channels expressed in Xenopus oocytes by Avdonin, V, Shibata, E F, Hoshi, T

“…Dihydropyridines (DHPs) are well known for their effects on L-typed voltage-dependent Ca2+ channels, However, these drugs also affect other voltage-dependent…”
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Regulation of caveolar cardiac sodium current by a single Gsalpha histidine residue by Palygin, Oleg A, Pettus, Janette M, Shibata, Erwin F

“…Cardiac sodium channels (voltage-gated Na(+) channel subunit 1.5) reside in both the plasmalemma and membrane invaginations called caveolae. Opening of the…”
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Sarcomere shortening in striated muscle occurs in stepwise fashion by POLLACK, GERALD H, IWAZUMI, TATSUO, TER KEURS, HENK E. D. J, SHIBATA, ERWIN F

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Modulation of rat cardiac sodium channel by the stimulatory G protein α subunit by Tong Lu, Hon-Chi Lee, Julia A Kabat, Erwin F Shibata

“…Modulation of cardiac sodium currents ( I Na ) by the G protein stimulatory α subunit (Gsα) was studied using patch-clamp techniques on freshly dissociated…”
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4 A calcium-activated chloride channel in rabbit coronary artery smooth muscle cells by Lamb, Fred S., Shibata, Erwin F.

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Acetylcholine reversal of isoproterenol-stimulated sodium currents in rabbit ventricular myocytes by MATSUDA, J. J, HON-CHI LEE, SHIBATA, E. F

“…We have recently shown that beta-adrenergic agonists enhance the cardiac sodium current (INa) in rabbits through dual G-protein regulatory pathways. To…”
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Reversal of lidocaine effects on sodium currents by isoproterenol in rabbit hearts and heart cells by HON-CHI LEE, MATSUDA, J. J, REYNERTSON, S. I, MARTINS, J. B, SHIBATA, E. F

“…We demonstrated recently that isoproterenol enhanced the cardiac voltage-dependent sodium currents (INa) in rabbit ventricular myocytes through dual G-protein…”
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Sodium current modulation by autonomic transmitters in isolated rabbit cardiac myocytes by Matsuda, James J., Lee, Hon-Chi, Shibata, Erwin F.

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Mechanism of alpha-2 adrenergic modulation of canine cardiac Purkinje action potential by Lee, H C, Cai, J J, Arnar, D O, Shibata, E F, Martins, J B

“…We reported recently that stimulation of postjunctional alpha-2 adrenergic receptors prolongs the action potential durations (APD) of isolated canine Purkinje…”
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Acetlcholine Reversal of Isoproterenol-Stimulated Sodium Currents in Rabbit Ventricular Myocytes by Matsuda, James J, Lee, Hon-Chi, Shibata, Erwin F

“…We have recently shown that β-adrenergic agonists enhance the cardiac sodium current (INa) in rabbits through dual G-protein regulatory pathways. To determine…”
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