Search Results - "Shibamura, Miho"
-
1
Longitudinal Trends of Prevalence of Neutralizing Antibody against Human Cytomegalovirus over the Past 30 Years in Japanese Women
Published in Japanese Journal of Infectious Diseases (30-09-2022)“…Neutralizing antibodies (NAbs) to human cytomegalovirus (HCMV) are associated with the risk of transplacental HCMV infection of the fetus in pregnant women…”
Get full text
Journal Article -
2
New Mechanism of Acyclovir Resistance in Herpes Simplex Virus 1, Which Has a UAG Stop Codon between the First and Second AUG Initiation Codons
Published in Japanese Journal of Infectious Diseases (30-11-2020)“…Morphological changes in the structure of the herpes simplex virus 1 (HSV-1) viral thymidine kinase (vTK) polypeptide usually lead to conferring acyclovir…”
Get full text
Journal Article -
3
A highly attenuated vaccinia virus strain LC16m8-based vaccine for severe fever with thrombocytopenia syndrome
Published in PLoS pathogens (01-02-2021)“…Severe fever with thrombocytopenia syndrome (SFTS) caused by a species Dabie bandavirus (formerly SFTS virus [SFTSV]) is an emerging hemorrhagic infectious…”
Get full text
Journal Article -
4
The effect of anesthetics on toll like receptor 9
Published in The FASEB journal (01-11-2020)“…Toll like receptors (TLRs) are critical receptors to respond to danger signals, and their functions are relevant in the perioperative period. We previously…”
Get full text
Journal Article -
5
Fatal SARS-CoV-2 Infection among Children, Japan, January-September 2022
Published in Emerging infectious diseases (01-08-2024)“…To determine the characteristics of pediatric patients 0–19 years of age who died after onset of SARS-CoV-2 infection in Japan during January 1–September 30,…”
Get full text
Journal Article -
6
Differences in the Likelihood of Acyclovir Resistance-Associated Mutations in the Thymidine Kinase Genes of Herpes Simplex Virus 1 and Varicella-Zoster Virus
Published in Antimicrobial agents and chemotherapy (01-05-2019)“…Acyclovir (ACV) resistance-associated mutations in two recombinant herpes simplex virus 1 (HSV-1) clones were compared. Recombinant HSV-1 lacking its thymidine…”
Get full text
Journal Article -
7
Development of a recombinant replication-deficient rabies virus-based bivalent-vaccine against MERS-CoV and rabies virus and its humoral immunogenicity in mice
Published in PloS one (07-10-2019)“…Middle East respiratory syndrome-coronavirus (MERS-CoV) is an emerging virus that causes severe disease with fatal outcomes; however, there are currently no…”
Get full text
Journal Article -
8
A Novel System for Constructing a Recombinant Highly-Attenuated Vaccinia Virus Strain (LC16m8) Expressing Foreign Genes and Its Application for the Generation of LC16m8-Based Vaccines against Herpes Simplex Virus 2
Published in Japanese Journal of Infectious Diseases (2018)“…A novel system was developed for generating highly attenuated vaccinia virus LC16m8 (m8, third-generation smallpox vaccine) that expresses foreign genes. The…”
Get full text
Journal Article -
9
Association of human cytomegalovirus (HCMV) neutralizing antibodies with antibodies to the HCMV glycoprotein complexes
Published in Virology journal (03-08-2020)“…Abstract Background Human cytomegalovirus (HCMV) causes asymptomatic infections, but also causes congenital infections when women were infected with HCMV…”
Get full text
Journal Article -
10
Acyclovir Sensitivity and Neurovirulence of Herpes Simplex Virus Type 1 with Amino Acid Substitutions in the Viral Thymidine Kinase Gene, Which Were Detected in the Patients with Intractable Herpes Simplex Encephalitis Previously Reported
Published in Japanese Journal of Infectious Diseases (30-09-2018)“…Several cases of herpes simplex encephalitis (HSE) caused by acyclovir (ACV)-resistant herpes simplex virus type 1 (HSV-1) have been reported. Amino acid…”
Get full text
Journal Article -
11
Construction and characterization of bacterial artificial chromosomes harboring the full-length genome of a highly attenuated vaccinia virus LC16m8
Published in PloS one (23-02-2018)“…LC16m8 (m8), a highly attenuated vaccinia virus (VAC) strain, was developed as a smallpox vaccine, and its safety and immunogenicity have been confirmed. Here,…”
Get full text
Journal Article -
12
Association between sensitivity of viral thymidine kinase-associated acyclovir-resistant herpes simplex virus type 1 and virulence
Published in Virology journal (21-03-2017)“…Acyclovir (ACV)-resistant (ACVr) herpes simplex virus type 1 (HSV-1) infections are concern in immunocompromised patients. Most clinical ACVr HSV-1 isolates…”
Get full text
Journal Article -
13
Mechanistic consideration of the effect of perioperative volatile anesthetics on phagocytes
Published in Clinical immunology (Orlando, Fla.) (01-01-2021)“…A growing literature has shown that volatile anesthetics are promiscuous molecules targeting multiple molecules, some of which are critical for immunological…”
Get full text
Journal Article -
14
Anesthetics isoflurane and sevoflurane attenuate flagellin-mediated inflammation in the lung
Published in Biochemical and biophysical research communications (11-06-2021)“…Isoflurane and sevoflurane are volatile anesthetics (VA) widely used in clinical practice to provide general anesthesia. We and others have previously shown…”
Get full text
Journal Article -
15
αDβ2 as a novel target of experimental polymicrobial sepsis
Published in Frontiers in immunology (18-11-2022)“…Since sepsis was defined three decades ago, it has been a target of intensive study. However, there is no specific sepsis treatment available, with its high…”
Get full text
Journal Article -
16
Protection of the third-dose and fourth-dose mRNA vaccines against SARS-CoV-2 Omicron subvariant: a systematic review and meta-analysis
Published in BMJ open (20-12-2023)“…ObjectivesThe rapid spread of the SARS-CoV-2 Omicron variant has raised concerns regarding waning vaccine-induced immunity and durability. We evaluated…”
Get full text
Journal Article -
17
GltS regulates biofilm formation in methicillin-resistant Staphylococcus aureus
Published in Communications biology (23-11-2022)“…Biofilm-based infection is a major healthcare burden. Methicillin-resistant Staphylococcus aureus (MRSA) is one of major organisms responsible for biofilm…”
Get full text
Journal Article -
18
Risk factors for pediatric surgical site infection following neurosurgical procedures for hydrocephalus: a retrospective single-center cohort study
Published in BMC anesthesiology (21-04-2021)“…Infection is a major complication following cerebral spinal fluid (CSF) diversion procedures for hydrocephalus. However, pediatric risk factors for surgical…”
Get full text
Journal Article -
19
Fatal SARS-CoV-2 Infection Among Children, Japan, January–September 20221
Published in Emerging infectious diseases (01-08-2024)“…To determine the characteristics of pediatric patients 0-19 years of age who died after onset of SARS-CoV-2 infection in Japan during January 1-September 30,…”
Get full text
Journal Article -
20
Application of next-generation sequencing to detect acyclovir-resistant herpes simplex virus type 1 variants at low frequency in thymidine kinase gene of the isolates recovered from patients with hematopoietic stem cell transplantation
Published in Journal of virological methods (01-01-2018)“…•A NGS was applied to detect variants at low frequency in HSV-1 TK genes.•The efficacy of the NGS assay was assessed in comparison to that of Sanger…”
Get full text
Journal Article