Search Results - "Shiba, Naoko"

Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts by Shiba, Yuji, Gomibuchi, Toshihito, Seto, Tatsuichiro, Wada, Yuko, Ichimura, Hajime, Tanaka, Yuki, Ogasawara, Tatsuki, Okada, Kenji, Shiba, Naoko, Sakamoto, Kengo, Ido, Daisuke, Shiina, Takashi, Ohkura, Masamichi, Nakai, Junichi, Uno, Narumi, Kazuki, Yasuhiro, Oshimura, Mitsuo, Minami, Itsunari, Ikeda, Uichi

“…Allogenic induced pluripotent stem cell-derived cardiomyocytes transplanted directly into infarcted cynomolgus monkey hearts show electrical coupling with host…”
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Comparison of the phenotypes of patients harboring in-frame deletions starting at exon 45 in the Duchenne muscular dystrophy gene indicates potential for the development of exon skipping therapy by Nakamura, Akinori, Shiba, Naoko, Miyazaki, Daigo, Nishizawa, Hitomi, Inaba, Yuji, Fueki, Noboru, Maruyama, Rika, Echigoya, Yusuke, Yokota, Toshifumi

“…Exon skipping therapy has recently received attention for its ability to convert the phenotype of lethal Duchenne muscular dystrophy (DMD) to a more benign…”
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Deletion of exons 3-9 encompassing a mutational hot spot in the DMD gene presents an asymptomatic phenotype, indicating a target region for multiexon skipping therapy by Nakamura, Akinori, Fueki, Noboru, Shiba, Naoko, Motoki, Hirohiko, Miyazaki, Daigo, Nishizawa, Hitomi, Echigoya, Yusuke, Yokota, Toshifumi, Aoki, Yoshitsugu, Takeda, Shin'ichi

“…Few cases of dystrophinopathy show an asymptomatic phenotype with mutations in the 5' (exons 3-7) hot spot in the Duchenne muscular dystrophy (DMD) gene. Our…”
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Intracoronary transplantation of pluripotent stem cell-derived cardiomyocytes: Inefficient procedure for cardiac regeneration by Kobayashi, Hideki, Tohyama, Shugo, Kanazawa, Hideaki, Ichimura, Hajime, Chino, Shuji, Tanaka, Yuki, Suzuki, Yota, Zhao, Jian, Shiba, Naoko, Kadota, Shin, Narita, Kazumasa, Naito, Takafumi, Seto, Tatsuichiro, Kuwahara, Koichiro, Shiba, Yuji, Fukuda, Keiichi

“…Advances in stem cell biology have facilitated cardiac regeneration, and many animal studies and several initial clinical trials have been conducted using…”
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Amelioration of intracellular Ca2+ regulation by exon-45 skipping in Duchenne muscular dystrophy-induced pluripotent stem cell-derived cardiomyocytes by Sato, Mitsuto, Shiba, Naoko, Miyazaki, Daigo, Shiba, Yuji, Echigoya, Yusuke, Yokota, Toshifumi, Takizawa, Hotake, Aoki, Yoshitsugu, Takeda, Shin’ichi, Nakamura, Akinori

“…Duchenne muscular dystrophy (DMD) is a devastating muscle disorder caused by frameshift mutations in the DMD gene. DMD involves cardiac muscle, and the…”
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Increased predominance of the matured ventricular subtype in embryonic stem cell-derived cardiomyocytes in vivo by Ichimura, Hajime, Kadota, Shin, Kashihara, Toshihide, Yamada, Mitsuhiko, Ito, Kuniaki, Kobayashi, Hideki, Tanaka, Yuki, Shiba, Naoko, Chuma, Shinichiro, Tohyama, Shugo, Seto, Tatsuichiro, Okada, Kenji, Kuwahara, Koichiro, Shiba, Yuji

“…Accumulating evidence suggests that human pluripotent stem cell-derived cardiomyocytes can affect “heart regeneration”, replacing injured cardiac scar tissue…”
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protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map by Elsen, Gina E., Hodge, Rebecca D., Bedogni, Francesco, Daza, Ray A. M., Nelson, Branden R., Shiba, Naoko, Reiner, Steven L., Hevner, Robert F.

“…The cortical area map is initially patterned by transcription factor (TF) gradients in the neocortical primordium, which define a “protomap” in the embryonic…”
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Importance of long-term motor function evaluation after prednisolone treatment for Duchenne muscular dystrophy by Nishizawa, Hitomi, Shiba, Naoko, Nakamura, Akinori

“…[Purpose] Motor function evaluation by physical therapists is considered a valuable tool to assess the progression of muscular dystrophies. Few reports have…”
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Clinical features of a female with WDR45 mutation complicated by infantile spasms: a case report and literature review by Morikawa, Manami, Takano, Kyoko, Motobayashi, Mitsuo, Shiba, Naoko, Kosho, Tomoki, Nakazawa, Yozo, Inaba, Yuji

“…Abstract We present a 3-year-old girl with beta-propeller protein-associated neurodegeneration (BPAN) who had a de novo heterozygous splice-site mutation of…”
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Mature human induced pluripotent stem cell-derived cardiomyocytes promote angiogenesis through alpha-B crystallin by Tanaka, Yuki, Kadota, Shin, Zhao, Jian, Kobayashi, Hideki, Okano, Satomi, Izumi, Masaki, Honda, Yusuke, Ichimura, Hajime, Shiba, Naoko, Uemura, Takeshi, Wada, Yuko, Chuma, Shinichiro, Nakada, Tsutomu, Tohyama, Shugo, Fukuda, Keiichi, Yamada, Mitsuhiko, Seto, Tatsuichiro, Kuwahara, Koichiro, Shiba, Yuji

“…Abstract Background Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) can be used to treat heart diseases; however, the optimal maturity…”
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Efficacy of exon-skipping therapy for DMD cardiomyopathy with mutations in actin binding domain 1 by Shiba, Naoko, Yang, Xiao, Sato, Mitsuto, Kadota, Shin, Suzuki, Yota, Agata, Masahiro, Nagamine, Kohei, Izumi, Masaki, Honda, Yusuke, Koganehira, Tomoya, Kobayashi, Hideki, Ichimura, Hajime, Chuma, Shinichiro, Nakai, Junichi, Tohyama, Shugo, Fukuda, Keiichi, Miyazaki, Daigo, Nakamura, Akinori, Shiba, Yuji

“…Exon-skipping therapy is a promising treatment strategy for Duchenne muscular dystrophy (DMD), which is caused by loss-of-function mutations in the DMD gene…”
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Differential roles of MMP-9 in early and late stages of dystrophic muscles in a mouse model of Duchenne muscular dystrophy by Shiba, Naoko, Miyazaki, Daigo, Yoshizawa, Takahiro, Fukushima, Kazuhiro, Shiba, Yuji, Inaba, Yuji, Imamura, Michihiro, Takeda, Shin'ichi, Koike, Kenichi, Nakamura, Akinori

“…Matrix metalloprotease (MMP)-9 is an endopeptidase associated with the pathogenesis of Duchenne muscular dystrophy (DMD). The precise function of MMP-9 in DMD…”
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Elevation of neuron specific enolase and brain iron deposition on susceptibility-weighted imaging as diagnostic clues for beta-propeller protein-associated neurodegeneration in early childhood: Additional case report and review of the literature by Takano, Kyoko, Shiba, Naoko, Wakui, Keiko, Yamaguchi, Tomomi, Aida, Noriko, Inaba, Yuji, Fukushima, Yoshimitsu, Kosho, Tomoki

“…Beta‐propeller protein‐associated neurodegeneration (BPAN), also known as static encephalopathy of childhood with neurodegeneration in adulthood (SENDA), is a…”
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Usefulness of continuous actigraph monitoring in the assessment of the effect of corticosteroid treatment for Duchenne muscular dystrophy: a case report by Nishizawa, Hitomi, Shiba, Naoko, Nakamura, Akinori

“…[Purpose] This study evaluated the effect of corticosteroid treatment on the daily activity of a patient with Duchenne muscular dystrophy using an actigraph…”
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Autism susceptibility candidate 2 ( Auts2) encodes a nuclear protein expressed in developing brain regions implicated in autism neuropathology by Bedogni, Francesco, Hodge, Rebecca D., Nelson, Branden R., Frederick, Erika A, Shiba, Naoko, Daza, Ray A., Hevner, Robert F.

“…Autism susceptibility candidate 2 ( Auts2) is a gene associated with autism and mental retardation, whose function is unknown. Expression of Auts2 mRNA and…”
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The effect of wearing night splints for one year on the standing motor function of patients with Duchenne muscular dystrophy by Nishizawa, Hitomi, Matsukiyo, Ayumi, Shiba, Naoko, Koinuma, Masayoshi, Nakamura, Akinori

“…[Purpose] To investigate the effect of night splints on the standing motor function and ankle dorsiflexion angles of patients with Duchenne muscular dystrophy…”
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Correlation Between White Matter Lesions and Intelligence Quotient in Patients With Congenital Cytomegalovirus Infection by Inaba, Yuji, MD, PhD, Motobayashi, Mitsuo, MD, PhD, Nishioka, Makoto, MD, Kaneko, Tomoki, MD, PhD, Yamauchi, Shoko, MD, Kawasaki, Yoichiro, MD, Shiba, Naoko, MD, PhD, Nishio, Shin-ya, PhD, Moteki, Hideaki, MD, PhD, Miyagawa, Maiko, MD, PhD, Takumi, Yutaka, MD, PhD, Usami, Shin-ichi, MD, PhD, Koike, Kenichi, MD, PhD

“…Abstract Background It is well known that congenital cytomegalovirus infection exhibits white matter and other types of lesions in magnetic resonance imaging…”
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Cardiac Sodium Channel Disease Modeling Using Patient-Derived Induced Pluripotent Stem Cells by Kadota, Shin, Shiba, Naoko, Shiba, Yuji

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Periodic sound-based 6-minute walk test forpatients with Duchenne muscular dystrophy:a preliminary study by Nishizawa, Hitomi, Genno, Hirokazu, Shiba, Naoko, Nakamura, Akinori

“…[Purpose] The purpose of this study was to verify if a periodic sound-based 6-minute walk test with the best periodic sound could be used to evaluate physical…”
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Successful treatment for West syndrome with severe combined immunodeficiency by Motobayashi, Mitsuo, Inaba, Yuji, Fukuyama, Tetsuhiro, Kurata, Takashi, Niimi, Taemi, Saito, Shoji, Shiba, Naoko, Nishimura, Takafumi, Shigemura, Tomonari, Nakazawa, Yozo, Kobayashi, Norimoto, Sakashita, Kazuo, Agematsu, Kazunaga, Ichikawa, Motoki, Koike, Kenichi

“…Abstract Several immune mechanisms are suspected in the unknown etiology of West syndrome (WS). We report a male infant who suffered from WS and X-linked…”
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