Search Results - "Shiah, I S"

Genome-wide association study of bipolar I disorder in the Han Chinese population by Lee, M T M, Chen, C H, Lee, C S, Chen, C C, Chong, M Y, Ouyang, W C, Chiu, N Y, Chuo, L J, Chen, C Y, Tan, H K L, Lane, H Y, Chang, T J, Lin, C H, Jou, S H, Hou, Y M, Feng, J, Lai, T J, Tung, C L, Chen, T J, Chang, C J, Lung, F W, Chen, C K, Shiah, I S, Liu, C Y, Teng, P R, Chen, K H, Shen, L J, Cheng, C S, Chang, T P, Li, C F, Chou, C H, Chen, C Y, Wang, K H T, Fann, C S J, Wu, J Y, Chen, Y T, Cheng, A T A

“…We report the first genome-wide association study in 1000 bipolar I patients and 1000 controls, with a replication of the top hits in another 409 cases and…”
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Serotonin in mania and in the mechanism of action of mood stabilizers: a review of clinical studies by Shiah, I-Shin, Yatham, Lakshmi N

“…Objectives: Serotonin (5‐hydroxytryptamine, 5‐HT) was implicated in the pathophysiology of manic‐depressive illness as early as 1958. Although extensive…”
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Effects of rapid tryptophan depletion in patients with seasonal affective disorder in natural summer remission by Lam, R W, Bowering, T A, Tam, E M, Grewal, A, Yatham, L N, Shiah, I S, Zis, A P

“…Serotonergic mechanisms have been proposed for the pathophysiology of seasonal affective disorder (SAD) and the therapeutic effect of bright-light treatment…”
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Effects of divalproex sodium on 5-HT1A receptor function in healthy human males : Hypothermic, hormonal, and behavioral responses to ipsapirone by SHIAH, I.-S, YATHAM, L. N, LAM, R. W, ZIS, A. P

“…Hypothermic and hormonal responses to a challenge with a selective 5-HT1A receptor agonist ipsapirone are considered to provide an index of 5-HT1A receptor…”
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Effects of light therapy on suicidal ideation in patients with winter depression by LAM, R. W, TAM, E. M, SHIAH, I.-S, YATHAM, L. N, ZIS, A. P

“…Recent case reports suggest that some patients with seasonal affective disorder (SAD) may become suicidal after initial treatment with light therapy. This…”
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Divalproex Sodium Attenuates Growth Hormone Response to Baclofen in Healthy Human Males by Shiah, M.D, I-Shin, Yatham, M.B.B.S., F.R.C.P.C, Lakshmi N., Lam, M.D., F.R.C.P.C, Raymond W., Zis, M.D., F.R.C.P.C, Athanasios P.

“…The effect of divalproex sodium (DVP) on γ-aminobutyric acid-B (GABAB) receptor function in humans was assessed by measuring growth hormone (GH) responses to a…”
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The lower limits of dexamethasone window in Chinese depressives by Shiah, I-Shin, Ko, Huei-Chen, Lu, Ru-Band

“…Background: Previous studies have shown wide variation in plasma dexamethasone (DEX) concentrations following a standard 1-mg dexamethasone suppression test…”
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Divalproex sodium increases plasma GABA levels in healthy volunteers by Shiah, I S, Yatham, L N, Baker, G B

“…The purpose of this study was to ascertain the effects of divalproex sodium (DVP), an anticonvulsant and mood stabilizer, on plasma gamma-aminobutyric acid…”
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Hypothermic, ACTH, and cortisol responses to ipsapirone in patients with mania and healthy controls by Yatham, Lakshmi N, Shiah, I-Shin, Lam, Raymond W, Tam, Edwin M, Zis, Athanasios P

“…Background: The selective 5-HT 1A receptor agonist ipsapirone causes dose-dependent decrease in body temperature and increase in adrenocorticotropic hormone…”
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A PET study of brain 5-HT2 receptors and their correlation with platelet 5-HT2 receptors in healthy humans by YATHAM, Lakshmi N, STEINER, Meir, LIDDLE, Peter F, SHIAH, I.-Shin, LAM, Raymond W, ZIS, Athanasios P, COOTE, Margaret

“…Platelets share many properties with brain serotonergic neurons such as active 5-hydroxytryptamine (5-HT) transport, 5-HT2 receptors, and mitochondrial…”
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Platelet 5-HT and plasma MHPG levels in patients with bipolar I and bipolar II depressions and normal controls by Shiah, I.-Shin, Ko, Huei-Chen, Lee, Jia-Fu, Lu, Ru-Band

“…Background: It has been suggested that platelet serotonin (5-HT) content may reflect aspects of the presynaptic reuptake of 5-HT, while plasma…”
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Sumatriptan-induced growth hormone release in patients with major depression, mania, and normal controls by Yatham, Lakshmi N., Zis, Athanasios P., Lam, Raymond W., Tam, Edwin, Shiah, I-Shin

“…The purpose of this study was to assess serotonergic function in patients with major depression or mania using sumatriptan, a novel 5-HT1D receptor agonist, as…”
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Plasma free 3-methoxy-4-hydroxyphenylglycol predicts response to fluoxetine by Ko, Huei-Chen, Lu, Ru-Band, Shiah, I-Shin, Hwang, Cheng-Chia

“…This study was designed to investigate the relationship between platelet serotonin (5-HT) and plasma free 3-methoxy-4-hydroxyphenylglycol (MHPG) measures in…”
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GABA function in mood disorders: An update and critical review by Shiah, I-Shin, Yatham, Lakshmi N.

“…Over the past twenty years, several lines of evidence from preclinical and clinical studies has accumulated suggesting that a GABA deficit may be involved in…”
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Growth hormone response to baclofen in patients with seasonal affective disorder: effects of light therapy by Shiah, I-Shin, A. Robertson, Heather, W. Lam, Raymond, N. Yatham, Lakshmi, M. Tam, Edwin, P. Zis, Athanasios

“…There is evidence for γ-aminobutyric acid (GABA) dysfunction in the pathophysiology and treatment response of patients with major depression, but this has not…”
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Seasonal depression: The dual vulnerability hypothesis revisited by Lam, Raymond W, Tam, Edwin M, Yatham, Lakshmi N, Shiah, I-Shin, Zis, Athanasios P

“…Objective: In DSM-IV, winter seasonal affective disorder (SAD) is classified as a seasonal pattern of recurrent major depressive episodes in winter with full…”
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Immune–inflammatory markers in patients with seasonal affective disorder: effects of light therapy by Leu, Sy-Jye, Shiah, I-Shin, Yatham, Lakshmi N., Cheu, Yech-Mei, Lam, Raymond W.

“…Background: There is increasing evidence that an activation of the immune–inflammatory system is involved in the pathophysiology of depressive disorders. The…”
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Acute psychosis following sustained release bupropion overdose by Wang, Tzong-Shi, Shiah, I-Shin, Yeh, Chin-Bin, Chang, Chuan-Chia

“…Bupropion is an antidepressant that is structurally related to amphetamines and enhances dopamine neurotransmission through inhibiting neuronal dopamine…”
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Decrease in Brain Serotonin 2 Receptor Binding in Patients With Major Depression Following Desipramine Treatment: A Positron Emission Tomography Study With Fluorine-18–Labeled Setoperone by Yatham, Lakshmi N, Liddle, Peter F, Dennie, Joelle, Shiah, I-Shin, Adam, Michael J, Lane, Carol J, Lam, Raymond W, Ruth, Thomas J

“…BACKGROUND The neuroreceptor changes involved in therapeutic efficacy of various antidepressants remain unclear. Preclinical studies have shown that long-term…”
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Effects of rapid tryptophan depletion on brain 5-HT(2) receptors: a PET study by Yatham, L N, Liddle, P F, Shiah, I S, Lam, R W, Adam, M J, Zis, A P, Ruth, T J

“…The mechanism by which rapid tryptophan depletion (RTD) paradigm induces depressive relapse in recently remitted patients with depression is unknown. To…”
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