Search Results - "Shi, Zhiao"
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WebGestalt 2017: a more comprehensive, powerful, flexible and interactive gene set enrichment analysis toolkit
Published in Nucleic acids research (03-07-2017)“…Functional enrichment analysis has played a key role in the biological interpretation of high-throughput omics data. As a long-standing and widely used web…”
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Fast network centrality analysis using GPUs
Published in BMC bioinformatics (12-05-2011)“…With the exploding volume of data generated by continuously evolving high-throughput technologies, biological network analysis problems are growing larger in…”
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WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013
Published in Nucleic acids research (01-07-2013)Get full text
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Proteogenomic characterization of human colon and rectal cancer
Published in Nature (London) (18-09-2014)“…Extensive genomic characterization of human cancers presents the problem of inference from genomic abnormalities to cancer phenotypes. To address this problem,…”
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Deciphering genomic alterations in colorectal cancer through transcriptional subtype-based network analysis
Published in PloS one (15-11-2013)“…Both transcriptional subtype and signaling network analyses have proved useful in cancer genomics research. However, these two approaches are usually applied…”
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WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013
Published in Nucleic acids research (01-07-2013)“…Functional enrichment analysis is an essential task for the interpretation of gene lists derived from large-scale genetic, transcriptomic and proteomic…”
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WebGestalt 2019: gene set analysis toolkit with revamped UIs and APIs
Published in Nucleic acids research (02-07-2019)“…WebGestalt is a popular tool for the interpretation of gene lists derived from large scale -omics studies. In the 2019 update, WebGestalt supports 12…”
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Robust task scheduling in non-deterministic heterogeneous computing systems
Published in 2006 IEEE International Conference on Cluster Computing (01-09-2006)“…The paper addresses the problem of matching and scheduling of DAG-structured application to both minimize the makespan and maximize the robustness in a…”
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Conference Proceeding -
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Feature Selection Methods for Protein Biomarker Discovery from Proteomics or Multiomics Data
Published in Molecular & cellular proteomics (01-01-2021)“…Untargeted mass spectrometry (MS)-based proteomics provides a powerful platform for protein biomarker discovery, but clinical translation depends on the…”
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Deep Learning in Proteomics
Published in Proteomics (Weinheim) (01-11-2020)“…Proteomics, the study of all the proteins in biological systems, is becoming a data‐rich science. Protein sequences and structures are comprehensively…”
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NetGestalt: integrating multidimensional omics data over biological networks
Published in Nature methods (01-07-2013)Get full text
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GLAD4U: deriving and prioritizing gene lists from PubMed literature
Published in BMC genomics (2012)“…Answering questions such as "Which genes are related to breast cancer?" usually requires retrieving relevant publications through the PubMed search engine,…”
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Proteogenomic characterization of pancreatic ductal adenocarcinoma
Published in Cell (16-09-2021)“…Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with poor patient survival. Toward understanding the underlying molecular alterations…”
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Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma
Published in Cancer cell (08-03-2021)“…We present a proteogenomic study of 108 human papilloma virus (HPV)-negative head and neck squamous cell carcinomas (HNSCCs). Proteomic analysis systematically…”
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WebGestalt 2024: faster gene set analysis and new support for metabolomics and multi-omics
Published in Nucleic acids research (05-07-2024)“…Enrichment analysis, crucial for interpreting genomic, transcriptomic, and proteomic data, is expanding into metabolomics. Furthermore, there is a rising…”
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Mathematical model development and simulation of in situ stabilization in lead-contaminated soils
Published in Journal of hazardous materials (12-10-2001)“…Stabilization and remediation of lead-contaminated soils has received considerable attention recently. Amending Pb-contaminated soils with phosphate as an in…”
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Proteogenomic Analysis of Human Colon Cancer Reveals New Therapeutic Opportunities
Published in Cell (02-05-2019)“…We performed the first proteogenomic study on a prospectively collected colon cancer cohort. Comparative proteomic and phosphoproteomic analysis of paired…”
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Graph Algorithms for Condensing and Consolidating Gene Set Analysis Results
Published in Molecular & cellular proteomics (09-08-2019)“…Weighted set cover and affinity propagation algorithms are used to combine results from multiple enrichment analyses. Weighted set cover first condenses…”
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Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy
Published in Cell (25-11-2020)“…The integration of mass spectrometry-based proteomics with next-generation DNA and RNA sequencing profiles tumors more comprehensively. Here this…”
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Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer
Published in Cell (28-07-2016)“…To provide a detailed analysis of the molecular components and underlying mechanisms associated with ovarian cancer, we performed a comprehensive…”
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