Search Results - "Shi, Y. Eric"
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Vitexins, Nature-Derived Lignan Compounds, Induce Apoptosis and Suppress Tumor Growth
Published in Clinical cancer research (15-08-2009)“…Purpose: Lignans such as secoisolariciresinol diglucoside in flaxseed, are metabolizes to bioactive mammalian lignans of END and ENL. Because mammalian lignans…”
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2
Complex roles of tissue inhibitors of metalloproteinases in cancer
Published in Oncogene (28-03-2002)“…Matrix metalloproteinases (MMPs) is tightly associated with extracellular matrix (ECM) turnover, which plays a very active role in tumor invasion and…”
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3
Synuclein gamma protects HER2 and renders resistance to Hsp90 disruption
Published in Molecular oncology (01-12-2014)“…Hsp90 is an important driver of stabilization and activation of several oncogenic proteins in many key pathways in oncogenesis, including HER2. The present…”
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4
Synuclein gamma predicts poor clinical outcome in colon cancer with normal levels of carcinoembryonic antigen
Published in BMC cancer (07-07-2010)“…Synuclein gamma (SNCG), initially identified as a breast cancer specific gene, is aberrantly expressed in many different malignant tumors but rarely expressed…”
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Expression of synuclein gamma indicates poor prognosis of triple-negative breast cancer
Published in Medical oncology (Northwood, London, England) (01-09-2013)“…Synuclein gamma (SNCG), previously identified as breast cancer–specific gene 1, is highly expressed in malignant cells but not in normal epithelium. Studies…”
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6
Activation of Stat5 and induction of a pregnancy‐like mammary gland differentiation by eicosapentaenoic and docosapentaenoic omega‐3 fatty acids
Published in The FEBS journal (01-07-2007)“…The protective effect of early pregnancy against breast cancer can be attributed to the transition from undifferentiated cells in the nulliparous to the…”
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7
Inhibition of tumor growth and metastasis of human breast cancer cells transfected with tissue inhibitor of metalloproteinase 4
Published in Oncogene (12-06-1997)“…We recently identified, cloned, and characterized a novel human tissue inhibitor of metalloproteinases-4, TIMP-4 (Greene et al., 1996). To determine if TIMP-4…”
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8
Induction of Mammary Gland Differentiation in Transgenic Mice by the Fatty Acid-binding Protein MRG
Published in The Journal of biological chemistry (21-11-2003)“…A mammary-derived growth inhibitor-related gene (MRG) was previously identified and characterized. MRG induces differentiation of mammary epithelial cells in…”
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9
γ Synuclein, a novel heat-shock protein-associated chaperone, stimulates ligand-dependent estrogen receptor α signaling and mammary tumorigenesis
Published in Cancer research (Chicago, Ill.) (01-07-2004)“…Synucleins are emerging as central players in the formation of pathologically insoluble deposits characteristic of neurodegenerative diseases. gamma synuclein…”
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10
Synuclein gamma inhibits the mitotic checkpoint function and promotes chromosomal instability of breast cancer cells
Published in Breast cancer research and treatment (01-11-2005)“…Aberrant expressions of the neuronal protein synuclein gamma (SNCG) in malignant mammary epithelial cells are strongly associated with the progression of…”
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11
Expression of neuronal protein synuclein gamma gene as a novel marker for breast cancer prognosis
Published in Breast cancer research and treatment (01-03-2007)“…Synucleins are emerging as central players in the fundamental neural processes and in the formation of pathologically insoluble deposits characteristic of…”
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12
Experimental Arthritis in Rats Induces Biomarkers of Periodontitis Which Are Ameliorated by Gene Therapy With Tissue Inhibitor of Matrix Metalloproteinases
Published in Journal of periodontology (1970) (01-02-2005)“…Background: Periodontal disease (PD) and rheumatoid arthritis (RA) share many common pathophysiologic features, but a clinical relationship between the two…”
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13
Stimulation of estrogen receptor signaling by γ synuclein
Published in Cancer research (Chicago, Ill.) (15-07-2003)“…Synucleins are emerging as central player in the fundamental neural processes and in the formation of pathologically insoluble deposits characteristic of…”
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14
Preparation and Characterization of Recombinant Tissue Inhibitor of Metalloproteinase 4 (TIMP-4)
Published in The Journal of biological chemistry (15-08-1997)“…TIMP-4, a novel human tissue inhibitor of metalloproteinase, was identified and cloned (Greene, J., Wang, M., Raymond, L. A., Liu, Y. E., Rosen, C., and Shi,…”
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15
Suppression of Breast Cancer Growth and Metastasis by a Serpin Myoepithelium-Derived Serine Proteinase Inhibitor Expressed in the Mammary Myoepithelial Cells
Published in Proceedings of the National Academy of Sciences - PNAS (30-03-1999)“…A serpin was identified in normal mammary gland by differential cDNA sequencing. In situ hybridization has detected this serpin exclusively in the…”
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16
TIMP-4 Is Regulated by Vascular Injury in Rats
Published in Circulation research (19-03-1999)“…The role of basement membrane-degrading matrix metalloproteinases (MMPs) in enabling vascular smooth muscle cell migration after vascular injury has been…”
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17
Inhibition of adjuvant‐induced arthritis by systemic tissue inhibitor of metalloproteinases 4 gene delivery
Published in Arthritis and rheumatism (01-12-2002)“…Objective An imbalance in the matrix metalloproteinase:tissue inhibitor of metalloproteinases (MMP:TIMP) ratio in favor of MMP appears to be an important…”
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Specific, High Affinity Binding of Tissue Inhibitor of Metalloproteinases-4 (TIMP-4) to the COOH-terminal Hemopexin-like Domain of Human Gelatinase A
Published in The Journal of biological chemistry (13-06-1997)“…The binding properties of the newly described tissue inhibitor of metalloproteinases-4 (TIMP-4) to progelatinase A and to the COOH-terminal hemopexin-like…”
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19
Stimulation of breast cancer invasion and metastasis by synuclein gamma
Published in Cancer research (Chicago, Ill.) (01-02-1999)“…We recently identified and cloned novel breast cancer-specific gene BCSG1 by direct differential cDNA sequencing. BCSG1 has a great sequence homology with the…”
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Identification of a breast cancer-specific gene, BCSG1, by direct differential cDNA sequencing
Published in Cancer research (Chicago, Ill.) (15-02-1997)“…A high-throughput direct-differential cDNA sequencing approach was employed to identify genes differentially expressed in normal breast as compared with breast…”
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