Search Results - "Shi, Xuanming"

Unexpected role for IGF-1 in starvation: Maintenance of blood glucose by Fang, Fei, Goldstein, Joseph L, Shi, Xuanming, Liang, Guosheng, Brown, Michael S

“…Wild-type (WT) mice maintain viable levels of blood glucose even when adipose stores are depleted by 6 d of 60% calorie restriction followed by a 23-h fast…”
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Regulation of Gli ciliary localization and Hedgehog signaling by the PY-NLS/karyopherin-β2 nuclear import system by Han, Yuhong, Xiong, Yue, Shi, Xuanming, Wu, Jiang, Zhao, Yun, Jiang, Jin

“…Hedgehog (Hh) signaling in vertebrates depends on primary cilia. Upon stimulation, Hh pathway components, including Gli transcription factors, accumulate at…”
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Alpha-tocopherol inhibits ferroptosis and promotes neural function recovery in rats with spinal cord injury via downregulating Alox15 by Zhu, Rui, Kang, Yu, Li, Qiangwei, Peng, Kai, Shi, Xuanming, Yin, Zongsheng, Xuan, Yong

“…Spinal cord injury (SCI) is a type of central nervous system (CNS) injury in which ferroptosis is becoming a promising target for treatment. Alpha-tocopherol…”
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Growth hormone acts on liver to stimulate autophagy, support glucose production, and preserve blood glucose in chronically starved mice by Fang, Fei, Shi, Xuanming, Brown, Michael S., Goldstein, Joseph L., Liang, Guosheng

“…When mice are subjected to 60% calorie restriction for several days, they lose nearly all of their body fat. Although the animals lack energy stores, their…”
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Hydrogen evolution reaction performance of the molybdenum disulfide/nickel–phosphorus composites in alkaline solution by Song, Laizhou, Wang, Xiuli, Wen, Fusheng, Niu, Lijing, Shi, Xuanming, Yan, Jiayun

“…The low phosphorus (LP), medium phosphorus (MP), and high phosphorus (HP) three nickel–phosphorus (NiP) powders were employed as supports of molybdenum…”
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Dual role of Brg chromatin remodeling factor in Sonic hedgehog signaling during neural development by Zhan, Xiaoming, Shi, Xuanming, Zhang, Zilai, Chen, Yu, Wu, Jiang I

“…Sonic hedgehog (Shh) signaling plays diverse roles during animal development and adult tissue homeostasis through differential regulation of Gli family…”
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Neuronal activity-induced BRG1 phosphorylation regulates enhancer activation by Kim, BongWoo, Luo, Yi, Zhan, Xiaoming, Zhang, Zilai, Shi, Xuanming, Yi, Jiaqing, Xuan, Zhenyu, Wu, Jiang

“…Neuronal activity-induced enhancers drive gene activation. We demonstrate that BRG1, the core subunit of SWI/SNF-like BAF ATP-dependent chromatin remodeling…”
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A novel homozygous missense mutation in AK7 causes multiple morphological anomalies of the flagella and oligoasthenoteratozoospermia by Xiang, Mingfei, Wang, Yu, Xu, Weilong, Zheng, Na, Deng, Hongshi, Zhang, Jingjing, Duan, Zongliu, Zha, Xiaomin, Zhang, Wenjun, Song, Gaojie, Shi, Xuanming, Wang, Fengsong, Cao, Yunxia, Zhu, Fuxi

“…Purpose To identify the genetic causes of multiple morphological anomalies of the flagella (MMAF) and oligoasthenoteratozoospermia (OAT). Methods Whole-exome…”
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Ropivacaine as a novel AKT1 specific inhibitor regulates the stemness of breast cancer by Ding, Lin, Jiang, Hui, Li, Qiangwei, Li, Qiushuang, Zhang, Tian-Tian, Shang, Limeng, Xie, Bin, Zhu, Yaling, Ding, Keshuo, Shi, Xuanming, Zhu, Tao, Zhu, Yong

“…Ropivacaine, a local anesthetic, exhibits anti-tumor effects in various cancer types. However, its specific functions and the molecular mechanisms involved in…”
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Pathogenesis of acephalic spermatozoa syndrome caused by splicing mutation and de novo deletion in TSGA10 by Xiang, Mingfei, Wang, Yu, Xu, Weilong, Zheng, Na, Zhang, Jingjing, Duan, Zongliu, Zha, Xiaomin, Shi, Xuanming, Wang, Fengsong, Cao, Yunxia, Zhu, Fuxi

“…Purpose To identify the genetic causes for acephalic spermatozoa syndrome. Methods Whole-exome sequencing was performed on the proband from a…”
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Targeting H3K27me3 demethylase to inhibit Shh signaling and cholesterol metabolism in medulloblastoma growth by Deng, Hongshi, Guo, Xueli, Feng, Na, Luo, Yi, Liu, Bei, Liu, Shuzhen, Wu, Jiang I, Shi, Xuanming

“…Previously we uncovered the epigenetic regulation of medulloblastoma that low levels of H3K27me3 are required for Shh target gene expression and…”
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Autism-Associated Chromatin Regulator Brg1/SmarcA4 Is Required for Synapse Development and Myocyte Enhancer Factor 2-Mediated Synapse Remodeling by Zhang, Zilai, Cao, Mou, Chang, Chia-Wei, Wang, Cindy, Shi, Xuanming, Zhan, Xiaoming, Birnbaum, Shari G., Bezprozvanny, Ilya, Huber, Kimberly M., Wu, Jiang I.

“…Synapse development requires normal neuronal activities and the precise expression of synapse-related genes. Dysregulation of synaptic genes results in…”
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Effect of Polymer Addition on the Structure and Hydrogen Evolution Reaction Property of Nanoflower-Like Molybdenum Disulfide by Zeng, Xianwen, Niu, Lijing, Song, Laizhou, Wang, Xiuli, Shi, Xuanming, Yan, Jiayun

“…Nano-structured molybdenum disulfide (MoS2) catalysts have been extensively developed for the hydrogen evolution reaction (HER). Herein, a novel hydrothermal…”
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C/EBP-beta drives expression of the nutritionally regulated promoter IA of the acetyl-CoA carboxylase-alpha gene in cattle by Shi, Xuanming, Liu, Shuzhen, Metges, Cornelia C., Seyfert, Hans-Martin

“…Acetyl-CoA carboxylase-alpha ( ACC-α) is the rate-limiting enzyme for de novo fatty acid synthesis. Among the four promoters expressing the bovine gene,…”
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Histone demethylase UTX/KDM6A enhances tumor immune cell recruitment, promotes differentiation and suppresses medulloblastoma by Yi, Jiaqing, Shi, Xuanming, Xuan, Zhenyu, Wu, Jiang

“…The deregulation of epigenetic pathways has been implicated as a critical step in tumorigenesis including in childhood brain tumor medulloblastoma. The…”
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Characterization and metabolism pathway of volatile compounds in walnut oil obtained from various ripening stages via HS-GC-IMS and HS-SPME-GC–MS by Xi, Bo-Nan, Zhang, Jing-Jing, Xu, Xiao, Li, Cong, Shu, Yu, Zhang, Yu, Shi, Xuanming, Shen, Yehua

“…[Display omitted] •Aromas in walnut oils with 5 ripeness were conducted by HS-GC–MS and HS-GC-IMS.•Ethyl hexanoate was detected firstly in walnut oil.•24 VOCs…”
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Identification of Ferroptotic Genes in Spinal Cord Injury at Different Time Points: Bioinformatics and Experimental Validation by Kang, Yu, Li, Qiangwei, Zhu, Rui, Li, Shuang, Xu, Xin, Shi, Xuanming, Yin, Zongsheng

“…Programmed cell death (PCD) is an important pathologic process after spinal cord injury (SCI). As a new type of PCD, ferroptosis is involved in the secondary…”
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An epigenetic switch induced by Shh signalling regulates gene activation during development and medulloblastoma growth by Shi, Xuanming, Zhang, Zilai, Zhan, Xiaoming, Cao, Mou, Satoh, Takashi, Akira, Shizuo, Shpargel, Karl, Magnuson, Terry, Li, Qingtian, Wang, Rongfu, Wang, Chaochen, Ge, Kai, Wu, Jiang

“…The Sonic hedgehog (Shh) signalling pathway plays important roles during development and in cancer. Here we report a Shh-induced epigenetic switch that…”
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PRC2 Heterogeneity Drives Tumor Growth in Medulloblastoma by Yi, Jiaqing, Kim, BongWoo, Shi, Xuanming, Zhan, Xiaoming, Lu, Q Richard, Xuan, Zhenyu, Wu, Jiang

“…Intratumor epigenetic heterogeneity is emerging as a key mechanism underlying tumor evolution and drug resistance. Epigenetic abnormalities frequently occur in…”
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Global analysis of lysine acetylome reveals the potential role of CCL18 in non‐small cell lung cancer by Kong, Shuai, Ding, Lu, Fan, Chenkun, Li, Yun, Wang, Chi, Wang, Ke, Xu, Weilong, Shi, Xuanming, Wu, Quan, Wang, Fengsong

“…C‐C motif chemokine 18 (CCL18) belongs to the chemokine CC family and is predominantly secreted by M2‐tumor‐associated macrophages. It has been reported to be…”
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