Search Results - "Shi, Xiaochu"

Influence of CRACC, a SLAM family receptor coupled to the adaptor EAT-2, on natural killer cell function by Shi, Xiaochu, Dong, Zhongjun, Veillette, André, Cruz-Munoz, Mario-Ernesto, Zhang, Shaohua

“…The biological function of the SLAM family receptor CRACC is not known. Using a CRACC-deficient mouse, Veillette and colleagues show that CRACC can activate or…”
Get full text

SAP expression in T cells, not in B cells, is required for humoral immunity by Veillette, André, Zhang, Shaohua, Shi, Xiaochu, Dong, Zhongjun, Davidson, Dominique, Zhong, Ming-Chao

“…SAP (also named SH2D1A) is an intracellular adaptor molecule expressed in T cells, natural killer (NK) cells, and some B cells. The SAP gene is mutated in…”
Get full text

Genetic Evidence Linking SAP, the X-Linked Lymphoproliferative Gene Product, to Src-Related Kinase FynT in TH2 Cytokine Regulation by Davidson, Dominique, Shi, Xiaochu, Zhang, Shaohua, Wang, Hao, Nemer, Mona, Ono, Nobuyuki, Ohno, Shinji, Yanagi, Yusuke, Veillette, André

“…SAP is an adaptor mutated in X-linked lymphoproliferative disease. It plays a critical role in T helper 2 (TH2) cytokine production. This function was…”
Get full text

Negative regulation of natural killer cell function by EAT-2, a SAP-related adaptor by Cruz-Munoz, Mario-Ernesto, Veillette, André, Taylor, James E R, Shi, Xiaochu, Yin, Luo, Roncagalli, Romain, Latour, Sylvain, Zhang, Shaohua, Chen, Riyan

“…EAT-2 is an adaptor expressed in innate immune cells, including natural killer (NK) cells. It is closely related to the adaptor SAP, which regulates signaling…”
Get full text

Association between SAP and FynT: Inducible SH3 Domain-Mediated Interaction Controlled by Engagement of the SLAM Receptor by Chen, Riyan, Latour, Sylvain, Shi, Xiaochu, Veillette, André

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Zidovudine-Didanosine Coexposure Potentiates DNA Incorporation of Zidovudine and Mutagenesis in Human Cells by Meng, Quanxin, Walker, Dale M., Olivero, Ofelia A., Shi, Xiaochu, Antiochos, Brendan B., Poirier, Miriam C., Walker, Vernon E.

“…Drug combinations that include nucleoside reverse transcriptase inhibitors (NRTIs) are remarkably effective in preventing maternal-viral transmission of HIV…”
Get full text

Relationships between DNA Incorporation, Mutant Frequency, and Loss of Heterozygosity at the TK Locus in Human Lymphoblastoid Cells Exposed to 3′-Azido-3′-deoxythymidine by Meng, Quanxin, Su, Ting, Olivero, Ofelia A., Poirier, Miriam C., Shi, Xiaochu, Ding, Xinxin, Walker, Vernon E.

“…3′-Azido-3′-deoxythymidine (AZT), a thymidine analogue widely used in the treatment of AIDS patients and for prevention of the onset of AIDS in…”
Get full text

Mutagenicity and loss of heterozygosity at the APRT locus in human lymphoblastoid cells exposed to 3′-azido-3′-deoxythymidine by Meng, Quanxin, Grosovsky, Andrew J., Shi, Xiaochu, Walker, Vernon E.

“…Previous experiments in our research group showed that 3′-azido-3′-deoxythymidine (AZT) caused increased mutant frequencies (Mfs) at the X-linked…”
Get full text

The Phosphatase PTP-PEST Promotes Secondary T Cell Responses by Dephosphorylating the Protein Tyrosine Kinase Pyk2 by Davidson, Dominique, Shi, Xiaochu, Zhong, Ming-Chao, Rhee, Inmoo, Veillette, André

“…PTP-PEST (encoded by Ptpn12) is an intracellular protein tyrosine phosphatase belonging to the same family as LYP. LYP inhibits secondary T cell responses by…”
Get full text

Transplacental mutagenicity of N-ethyl-N-nitrosourea at the hprt locus in T-lymphocytes of exposed B6C3F1 mice by Sussman, Hillary E., Bauer, Michael J., Shi, Xiaochu, Judice, Stephen A., Albertini, Richard J., Walker, Vernon E.

“…Previous studies have compared age‐related differences in total mutagenic burden in mice of differing age (preweanling, weanling, or young adult) after single…”
Get full text

Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation by Veillette, André, Latour, Sylvain, Roncagalli, Romain, Chen, Riyan, Bakinowski, Marcin, Shi, Xiaochu, Schwartzberg, Pamela L, Davidson, Dominique

“…SAP (or SH2D1A), an adaptor-like molecule expressed in immune cells, is composed almost exclusively of a Src homology 2 (SH2) domain. In humans, SAP is mutated…”
Get full text

Genetic evidence linking SAP, the X-linked lymphoproliferative gene product, to Src-related kinase FynT in T(H)2 cytokine regulation by Davidson, Dominique, Shi, Xiaochu, Zhang, Shaohua, Wang, Hao, Nemer, Mona, Ono, Nobuyuki, Ohno, Shinji, Yanagi, Yusuke, Veillette, André

“…SAP is an adaptor mutated in X-linked lymphoproliferative disease. It plays a critical role in T helper 2 (T(H)2) cytokine production. This function was…”
Get full text

Genetic Evidence Linking SAP, the X-Linked Lymphoproliferative Gene Product, to Src-Related Kinase FynT in T H2 Cytokine Regulation by Davidson, Dominique, Shi, Xiaochu, Zhang, Shaohua, Wang, Hao, Nemer, Mona, Ono, Nobuyuki, Ohno, Shinji, Yanagi, Yusuke, Veillette, André

“…SAP is an adaptor mutated in X-linked lymphoproliferative disease. It plays a critical role in T helper 2 (T H2) cytokine production. This function was…”
Get full text

Detection of cyclophosphamide-induced mutations at theHprt but not thelacI locus in splenic lymphocytes of exposed mice by Walker, Vernon E., Andrews, Julie L., Upton, Patricia B., Skopek, Thomas R., deBoer, Johan G., Walker, Dale M., Shi, Xiaochu, Sussman, Hillary E., Gorelick, Nancy J.

Get full text

Detection of cyclophosphamide-induced mutations at the Hprt but not the lacI locus in splenic lymphocytes of exposed mice: Transgenics by WALKER, V. E, ANDREWS, J. L, UPTON, P. B, SKOPEK, T. R, DEBOER, J. G, WALKER, D. M, XIAOCHU SHI, SUSSMAN, H. E, GORELICK, N. J

Get full text

Detection of Cyclophosphamide-Induced Mutations at the Hprt But Not the lacI Locus in Splenic Lymphocytes of Exposed Mice by Walker, V E, Andrews, J L, Upton, P B, Skopek, T R, deBoer, J G, Walker, D M, Shi, Xiaochu, Sussman, HE, Gorelick, N J

“…The relative sensitivities and specificities of the endogenous Hprt gene and the lacI transgene as mutational targets were evaluated in splenic lymphocytes…”
Get full text

Detection of cyclophosphamide-induced mutations at the Hprt but not the lacI locus in splenic lymphocytes of exposed mice by Walker, Vernon E., Andrews, Julie L., Upton, Patricia B., Skopek, Thomas R., deBoer, Johan G., Walker, Dale M., Shi, Xiaochu, Sussman, Hillary E., Gorelick, Nancy J.

“…The relative sensitivities and specificities of the endogenous Hprt gene and the lacI transgene as mutational targets were evaluated in splenic lymphocytes…”
Get full text