Search Results - "Shi, Wanliang"

Activity of Pyrazinamide against Mycobacterium tuberculosis at Neutral pH in PZA-S1 Minimal Medium by Shi, Wanliang

“…Susceptibility testing of tuberculosis (TB) drugs on is essential for the rapid detection of strains resistant to the drugs, providing the patient with…”
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The molecular basis of pyrazinamide activity on Mycobacterium tuberculosis PanD by Sun, Qingan, Li, Xiaojun, Perez, Lisa M., Shi, Wanliang, Zhang, Ying, Sacchettini, James C.

“…Pyrazinamide has been a mainstay in the multidrug regimens used to treat tuberculosis. It is active against the persistent, non-replicating mycobacteria…”
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An optimized SYBR Green I/PI assay for rapid viability assessment and antibiotic susceptibility testing for Borrelia burgdorferi by Feng, Jie, Wang, Ting, Zhang, Shuo, Shi, Wanliang, Zhang, Ying

“…Lyme disease caused by Borrelia burgdorferi is the most common tick-borne disease in the US and Europe. Unlike most bacteria, measurements of growth and…”
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Pyrazinamide Inhibits Trans-Translation in Mycobacterium tuberculosis by Shi, Wanliang, Zhang, Xuelian, Jiang, Xin, Yuan, Haiming, Lee, Jong Seok, Barry, Clifton E., Wang, Honghai, Zhang, Wenhong, Zhang, Ying

“…Pyrazinamide (PZA) is a first-line tuberculosis drug that plays a unique role in shortening the duration of tuberculosis chemotherapy. PZA is hydrolyzed…”
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Effect of different drugs and drug combinations on killing stationary phase and biofilms recovered cells of Bartonella henselae in vitro by Zheng, Xiaoyan, Ma, Xiao, Li, Tingting, Shi, Wanliang, Zhang, Ying

“…Bartonella henselae is a Gram-negative bacterium transmitted to humans by a scratch from cat in the presence of ectoparasites. Humans infected with B. henselae…”
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Identification of Genes Involved in Bacteriostatic Antibiotic-Induced Persister Formation by Cui, Peng, Niu, Hongxia, Shi, Wanliang, Zhang, Shuo, Zhang, Wenhong, Zhang, Ying

“…Persister cells are metabolically quiescent multi-drug tolerant fraction of a genetically sensitive bacterial population and are thought to be responsible for…”
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Identification of essential oils with activity against stationary phase Staphylococcus aureus by Xiao, Shuzhen, Cui, Peng, Shi, Wanliang, Zhang, Ying

“…Staphylococcus aureus is the most dominant human pathogen, responsible for a variety of chronic and severe infections. There is mounting evidence that…”
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Aspartate decarboxylase (PanD) as a new target of pyrazinamide in Mycobacterium tuberculosis by Shi, Wanliang, Chen, Jiazhen, Feng, Jie, Cui, Peng, Zhang, Shuo, Weng, Xinhua, Zhang, Wenhong, Zhang, Ying

“…Pyrazinamide (PZA) is a frontline anti-tuberculosis drug that plays a crucial role in the treatment of both drug-susceptible and multidrug-resistant…”
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Energy production genes sucB and ubiF are involved in persister survival and tolerance to multiple antibiotics and stresses in Escherichia coli by Ma, Chao, Sim, Shuzhen, Shi, Wanliang, Du, Lijun, Xing, Dongming, Zhang, Ying

“…Persisters are a small population of slowly growing or nongrowing bacteria that are phenotypically resistant to antibiotics, but the mechanisms involved are…”
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Mutations in Efflux Pump Rv1258c (Tap) Cause Resistance to Pyrazinamide, Isoniazid, and Streptomycin in M. tuberculosis by Liu, Jiayun, Shi, Wanliang, Zhang, Shuo, Hao, Xiaoke, Maslov, Dmitry A, Shur, Kirill V, Bekker, Olga B, Danilenko, Valery N, Zhang, Ying

“…Although drug resistance in is mainly caused by mutations in drug activating enzymes or drug targets, there is increasing interest in the possible role of…”
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Genetic basis of virulence attenuation revealed by comparative genomic analysis of Mycobacterium tuberculosis strain H37Ra versus H37Rv by Zheng, Huajun, Lu, Liangdong, Wang, Bofei, Pu, Shiying, Zhang, Xianglin, Zhu, Genfeng, Shi, Wanliang, Zhang, Lu, Wang, Honghai, Wang, Shengyue, Zhao, Guoping, Zhang, Ying

“…Tuberculosis, caused by Mycobacterium tuberculosis, remains a leading infectious disease despite the availability of chemotherapy and BCG vaccine. The commonly…”
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PhoY2 but not PhoY1 is the PhoU homologue involved in persisters in Mycobacterium tuberculosis by Shi, Wanliang, Zhang, Ying

“…Objectives Mycobacterial persistence is thought to be the underlying cause of the current lengthy tuberculosis therapy and latent infection. Despite some…”
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Glycerol uptake is important for L-form formation and persistence in Staphylococcus aureus by Han, Jian, He, Lili, Shi, Wanliang, Xu, Xiaogang, Wang, Sen, Zhang, Shuo, Zhang, Ying

“…S. aureus is a significant human pathogen and has previously been shown to form cell wall deficient forms or L-forms in vitro and in vivo during infection…”
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Genetic Screen Reveals the Role of Purine Metabolism in Staphylococcus aureus Persistence to Rifampicin by Yee, Rebecca, Cui, Peng, Shi, Wanliang, Feng, Jie, Zhang, Ying

“…Chronic infections with Staphylococcus aureus such as septicemia, osteomyelitis, endocarditis, and biofilm infections are difficult to treat because of…”
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Identification of novel activity against Borrelia burgdorferi persisters using an FDA approved drug library by Feng, Jie, Wang, Ting, Shi, Wanliang, Zhang, Shuo, Sullivan, David, Auwaerter, Paul G, Zhang, Ying

“…Although antibiotic treatment for Lyme disease is effective in the majority of cases, especially during the early phase of the disease, a minority of patients…”
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Mutation in clpC1 encoding an ATP-dependent ATPase involved in protein degradation is associated with pyrazinamide resistance in Mycobacterium tuberculosis by Zhang, Shuo, Chen, Jiazhen, Shi, Wanliang, Cui, Peng, Zhang, Jia, Cho, Sanghyun, Zhang, Wenhong, Zhang, Ying

“…Emerging Microbes & Infections (2017) 6, e8; doi: 10.1038/emi.2017.1 ; published online 15 February 2017…”
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Selective Essential Oils from Spice or Culinary Herbs Have High Activity against Stationary Phase and Biofilm Borrelia burgdorferi by Feng, Jie, Zhang, Shuo, Shi, Wanliang, Zubcevik, Nevena, Miklossy, Judith, Zhang, Ying

“…Although the majority of patients with acute Lyme disease can be cured with the standard 2-4 week antibiotic treatment, about 10-20% of patients continue…”
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Evaluation of Disulfiram Drug Combinations and Identification of Other More Effective Combinations against Stationary Phase Borrelia burgdorferi by Alvarez-Manzo, Hector S, Zhang, Yumin, Shi, Wanliang, Zhang, Ying

“…Lyme disease, caused by , is the most common vector-borne disease in USA, and 10-20% of patients will develop persistent symptoms despite treatment…”
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Identification of FDA-Approved Drugs with Activity against Stationary Phase Bartonella henselae by Li, Tingting, Feng, Jie, Xiao, Shuzhen, Shi, Wanliang, Sullivan, David, Zhang, Ying

“…can cause various infections in humans, ranging from benign and self-limiting diseases to severe and life-threatening diseases as well as persistent infections…”
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Identification of Essential Oils Including Garlic Oil and Black Pepper Oil with High Activity against Babesia duncani by Zhang, Yumin, Bai, Chunxiang, Shi, Wanliang, Alvarez-Manzo, Hector, Zhang, Ying

“…Some evidence indicated that human babesiosis caused by Babesia duncani has spread widely in North America. However, current therapeutic regimens (atovaquone +…”
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