Search Results - "Shi, Stone"

Native and Denaturing MS Protein Deconvolution for Biopharma: Monoclonal Antibodies and Antibody–Drug Conjugates to Polydisperse Membrane Proteins and Beyond by Campuzano, Iain D. G, Robinson, John H, Hui, John O, Shi, Stone D.-H, Netirojjanakul, Chawita, Nshanian, Michael, Egea, Pascal F, Lippens, Jennifer L, Bagal, Dhanashri, Loo, Joseph A, Bern, Marshall

“…Electrospray ionization mass spectrometry (ESI-MS) is a ubiquitously used analytical method applied across multiple departments in biopharma, ranging from…”
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Institutional fragility and outward foreign direct investment from China by Shi, Weilei (Stone), Li Sun, Sunny, Yan, Daying, Zhu, Zhu

“…We develop the concept of institutional fragility to investigate the outward foreign direct investment (OFDI) behavior of firms from emerging economies. When…”
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Social network contingency, symbolic management, and boundary stretching by MARKÓCZY, LÍVIA, LI SUN, SUNNY, PENG, MIKE W., SHI, WEILEI (STONE), RÉN, BING

“…A firm's structural position within corporate networks may affect the extent to which it engages in boundary stretching practices. Since social norms support…”
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Multiplex measurement of twelve tumor markers using a GMR multi-biomarker immunoassay biosensor by Gao, Yang, Huo, Weisong, Zhang, Lei, Lian, Jie, Tao, Wei, Song, Chuan, Tang, Jinping, Shi, Stone, Gao, Yunhua

“…Tumor markers play an important role in the early diagnosis and therapeutic effect monitoring of tumors. Combined detection of multiple tumor markers is a…”
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High-resolution mass spectrometry confirms the presence of a hydroxyproline (Hyp) post-translational modification in the GGGGP linker of an Fc-fusion protein by Spahr, Chris, Gunasekaran, Kannan, Walker, Kenneth W, Shi, Stone D-H

“…Flexible and protease resistant (G4S) linkers are used extensively in protein engineering to connect various protein domains. Recently, several groups have…”
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Quantitative Phosphoproteomic Analysis of the STAT3/IL-6/HIF1α Signaling Network: An Initial Study in GSC11 Glioblastoma Stem Cells by Nilsson, Carol L, Dillon, Roslyn, Devakumar, Arugadoss, Shi, Stone D.-H, Greig, Michael, Rogers, John C, Krastins, Bryan, Rosenblatt, Michael, Kilmer, Gregory, Major, Michael, Kaboord, Barbara J, Sarracino, David, Rezai, Taha, Prakash, Amol, Lopez, Mary, Ji, Yongjie, Priebe, Waldemar, Lang, Frederick F, Colman, Howard, Conrad, Charles A

“…Initiation and maintenance of several cancers including glioblastoma (GBM) may be driven by a small subset of cells called cancer stem cells (CSCs). CSCs may…”
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Steady-State Kinetic and Inhibition Studies of the Mammalian Target of Rapamycin (mTOR) Kinase Domain and mTOR Complexes by Tao, Zhihua, Barker, John, Shi, Stone D.-H, Gehring, Michael, Sun, Shaoxian

“…The mammalian target of rapamycin (mTOR) is a Ser/Thr protein kinase and a major controller of cell growth. In cells, mTOR forms two distinct multiprotein…”
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Discovery, characterization, and remediation of a C-terminal Fc-extension in proteins expressed in CHO cells by Spahr, Christopher S, Daris, Mark E, Graham, Kevin C, Soriano, Brian D, Stevens, Jennitte L, Shi, Stone D-H

“…Protein-based biotherapeutics are produced in engineered cells through complex processes and may contain a wide variety of variants and post-translational…”
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Next generation Fc scaffold for multispecific antibodies by Estes, Bram, Sudom, Athena, Gong, Danyang, Whittington, Douglas A., Li, Vivian, Mohr, Christopher, Li, Danqing, Riley, Timothy P., Shi, Stone D.-H., Zhang, Jun, Garces, Fernando, Wang, Zhulun

“…Bispecific antibodies (Bispecifics) demonstrate exceptional clinical potential to address some of the most complex diseases. However, Bispecific production in…”
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Embracing non‐Western Contexts in Management Scholarship by Wickert, Christopher, Potočnik, Kristina, Prashantham, Shameen, Shi, Weilei (Stone), Snihur, Yuliya

“…Management is a global phenomenon. Yet, the vast majority of empirical investigations and theoretical explanations of management, managers and those being…”
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SNP rs10420324 in the AMPA receptor auxiliary subunit TARP γ-8 regulates the susceptibility to antisocial personality disorder by Peng, Shi-Xiao, Wang, Yue-Ying, Zhang, Min, Zang, Yan-Yu, Wu, Dan, Pei, Jingwen, Li, Yansong, Dai, Jiapei, Guo, Xiaoyun, Luo, Xingguang, Zhang, Ning, Yang, Jian-Jun, Zhang, Chen, Gao, Xiang, Liu, Na, Shi, Yun Stone

“…In the brain, AMPA receptors mediate fast excitatory neurotransmission, the dysfunction of which leads to neuropsychiatric disorders. Synaptic function of AMPA…”
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An institution-based view of global IPR history by Peng, Mike W, Ahlstrom, David, Carraher, Shawn M, Shi, Weilei (Stone)

“…Leveraging the use of history to advance international business research, this article focuses on the crucial debate over intellectual property rights (IPR)…”
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A Temporal Perspective of Merger and Acquisition and Strategic Alliance Initiatives: Review and Future Direction by Shi, Weilei (Stone), Sun, Jing, Prescott, John E.

“…The incorporation of a temporal perspective in merger and acquisition (M&A) and alliance research has gained increasing popularity. Since a temporal…”
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THE CONTINUING IMPORTANCE OF POLITICAL TIES IN CHINA by SHI, WEILEI (STONE), MARKÓCZY, LÍVIA, STAN, CIPRIAN V.

“…Our paper is a starting point for further discussions on the value of political ties in China, their evolutionary trajectory along the process of…”
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A Novel High-Sensitivity Cardiac Multibiomarker Detection System Based on Microfluidic Chip and GMR Sensors by Huo, Weisong, Gao, Yuzhe, Zhang, Lei, Shi, Stone, Gao, Yunhua

“…We have developed a novel cardiac multibiomarker detection system, wherein cardiac biomarkers NT-proBNP and cTnI could be detected simultaneously in 20 min…”
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Protected hinge in the immunoglobulin G2‐A2 disulfide isoform by Liu, Yaoqing Diana, Chou, Robert Y.‐T., Dillon, Thomas M., Poppe, Leszek, Spahr, Chris, Shi, Stone D. H., Flynn, Gregory C.

“…Human IgG2 consists of disulfide‐mediated structural isoforms, classified by the number of Fab arms disulfide‐linked to the heavy chain hinge. In the IgG2‐B…”
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O-Glycosylation of glycine-serine linkers in recombinant Fc-fusion proteins: Attachment of glycosaminoglycans and other intermediates with phosphorylation at the xylose sugar subunit by Spahr, Chris, Shi, Stone D-H, Lu, Hsieng S

“…A xylose-based glycosaminoglycan (GAG) core was recently identified at a Ser residue in the linker sequence of a recombinant Fc fusion protein. The linker…”
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Phosphopeptide/Phosphoprotein Mapping by Electron Capture Dissociation Mass Spectrometry by Shi, Stone D.-H, Hemling, Mark E, Carr, Steven A, Horn, David M, Lindh, Ingemar, McLafferty, Fred W

“…Of methods for dissociation of multiply charged peptide and protein ions, electron capture dissociation (ECD) has the advantages of cleaving between a high…”
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Scaling MS plateaus with high-resolution FT-ICRMS by MARSHALL, Alan G, HENDRICKSON, Christopher L, SHI, Stone D.-H

“…Marshall, Hendrickson, and Shi consider the new molecular information that becomes accessible as instrumental mass resolving power "climbs each step" by…”
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Supercritical Fluid Chromatography Reduction of Hydrogen/Deuterium Back Exchange in Solution-Phase Hydrogen/Deuterium Exchange with Mass Spectrometric Analysis by Emmett, Mark R, Kazazic, Sasa, Marshall, Alan G, Chen, Wei, Shi, Stone D.-H, Bolaños, Ben, Greig, Michael J

“…The single biggest problem with solution-phase H/D exchange as a mass spectrometric probe of surface exposure in a protein (or protein complex) is…”
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