Search Results - "Shi, SongTing"

Antisense-oligonucleotide mediated exon skipping in activin-receptor-like kinase 2: inhibiting the receptor that is overactive in fibrodysplasia ossificans progressiva by Shi, Songting, Cai, Jie, de Gorter, David J J, Sanchez-Duffhues, Gonzalo, Kemaladewi, Dwi U, Hoogaars, Willem M H, Aartsma-Rus, Annemieke, 't Hoen, Peter A C, ten Dijke, Peter

“…Fibrodysplasia ossificans progressiva (FOP) is a rare heritable disease characterized by progressive heterotopic ossification of connective tissues, for which…”
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Overactive bone morphogenetic protein signaling in heterotopic ossification and Duchenne muscular dystrophy by Shi, SongTing, de Gorter, David J. J, Hoogaars, Willem M. H, t Hoen, Peter A. C, ten Dijke, Peter

“…Bone morphogenetic proteins (BMPs) are important extracellular cytokines that play critical roles in embryogenesis and tissue homeostasis. BMPs signal via…”
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BMP antagonists enhance myogenic differentiation and ameliorate the dystrophic phenotype in a DMD mouse model by Shi, SongTing, Hoogaars, Willem M.H, de Gorter, David J.J, van Heiningen, Sandra H, Lin, Herbert Y, Hong, Charles C, Kemaladewi, Dwi U, Aartsma-Rus, Annemieke, ten Dijke, Peter, t Hoen, Peter A.C

“…Abstract Duchenne Muscular Dystrophy (DMD) is an X-linked lethal muscle wasting disease characterized by muscle fiber degeneration and necrosis. The…”
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760-P: Discovery of GSBR-1290, a Highly Potent, Orally Available, Novel Small Molecule GLP-1 Receptor Agonist by MAO, TING, MENG, QINGHUA, ZHANG, HAIZHEN, ZHANG, JINQIANG J., SHI, SONGTING, GUAN, ZHIBO, JIANG, XINGLONG, ZHANG, FANG, LEI, HUI, LIN, XICHEN

“…Peptidic glucagon-like peptide 1 receptor agonists (GLP-1RAs) are established treatments for patients with Type 2 Diabetes Mellitus (T2DM) and obesity…”
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Structural insight into apelin receptor-G protein stoichiometry by Yue, Yang, Liu, Lier, Wu, Li-Jie, Wu, Yiran, Wang, Ling, Li, Fei, Liu, Junlin, Han, Gye-Won, Chen, Bo, Lin, Xi, Brouillette, Rebecca L., Breault, Émile, Longpré, Jean-Michel, Shi, Songting, Lei, Hui, Sarret, Philippe, Stevens, Raymond C., Hanson, Michael A., Xu, Fei

“…The technique of cryogenic-electron microscopy (cryo-EM) has revolutionized the field of membrane protein structure and function with a focus on the dominantly…”
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Identification of a Key Residue Mediating Bone Morphogenetic Protein (BMP)-6 Resistance to Noggin Inhibition Allows for Engineered BMPs with Superior Agonist Activity by Song, Kening, Krause, Carola, Shi, Songting, Patterson, Marilyn, Suto, Robert, Grgurevic, Lovorka, Vukicevic, Slobodan, van Dinther, Maarten, Falb, Dean, ten Dijke, Peter, Alaoui-Ismaili, Moulay Hicham

“…Bone morphogenetic proteins (BMPs) are used clinically to induce new bone formation in spinal fusions and long bone non-union fractures. However, large amounts…”
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Visualizing Data using GTSNE by Shi, Songting

“…We present a new method GTSNE to visualize high-dimensional data points in the two dimensional map. The technique is a variation of t-SNE that produces better…”
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Visualizing Data Velocity using DSNE by Shi, Songting

“…We present a new technique called "DSNE" which learns the velocity embeddings of low dimensional map points when given the high-dimensional data points with…”
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Wnt/β-catenin signaling changes C2C12 myoblast proliferation and differentiation by inducing Id3 expression by Zhang, Long, Shi, Songting, Zhang, Juan, Zhou, Fangfang, ten Dijke, Peter

“…► Expression of Id3 but not Id1 is induced by Wnt3a stimulation in C2C12 cells. ► Wnt3a induces Id3 expression via canonical Wnt/β-catenin pathway. ►…”
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A Tutorial on the Mathematical Model of Single Cell Variational Inference by Shi, Songting

“…As the large amount of sequencing data accumulated in past decades and it is still accumulating, we need to handle the more and more sequencing data. As the…”
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Wnt/{beta}-catenin signaling changes C2C12 myoblast proliferation and differentiation by inducing Id3 expression by Zhang, Long, Shi, Songting, Zhang, Juan, Zhou, Fangfang, Dijke, Peter ten

“…Highlights: Black-Right-Pointing-Pointer Expression of Id3 but not Id1 is induced by Wnt3a stimulation in C2C12 cells. Black-Right-Pointing-Pointer Wnt3a…”
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Antisense-Oligonucleotide Mediated Exon Skipping in Activin-Receptor-Like Kinase 2: Inhibiting the Receptor That Is Overactive in Fibrodysplasia Ossificans Progressiva. e69096 by Shi, SongTing, Cai, Jie, Gorter, J Jde, Sanchez-Duffhues, Gonzalo, Kemaladewi, Dwi U, Hoogaars, Willem MH, Aartsma-Rus, Annemieke, Hoen, A C't, Dijke, Peter ten

“…Fibrodysplasia ossificans progressiva (FOP) is a rare heritable disease characterized by progressive heterotopic ossification of connective tissues, for which…”
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Learning the Sparse and Low Rank PARAFAC Decomposition via the Elastic Net by Shi, Songting, Li, Xiang, Sitek, Arkadiusz, Li, Quanzheng

“…In this article, we derive a Bayesian model to learning the sparse and low rank PARAFAC decomposition for the observed tensor with missing values via the…”
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