Search Results - "Shi, Senlin"

Resetting histone modifications during human parental-to-zygotic transition by Xia, Weikun, Xu, Jiawei, Yu, Guang, Yao, Guidong, Xu, Kai, Ma, Xueshan, Zhang, Nan, Liu, Bofeng, Li, Tong, Lin, Zili, Chen, Xia, Li, Lijia, Wang, Qiujun, Shi, Dayuan, Shi, Senlin, Zhang, Yile, Song, Wenyan, Jin, Haixia, Hu, Linli, Bu, Zhiqin, Wang, Yang, Na, Jie, Xie, Wei, Sun, Ying-Pu

“…Histone modifications regulate gene expression and development. To address how they are reprogrammed in human early development, we investigated key histone…”
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Chromatin analysis in human early development reveals epigenetic transition during ZGA by Wu, Jingyi, Xu, Jiawei, Liu, Bofeng, Yao, Guidong, Wang, Peizhe, Lin, Zili, Huang, Bo, Wang, Xuepeng, Li, Tong, Shi, Senlin, Zhang, Nan, Duan, Fuyu, Ming, Jia, Zhang, Xiangyang, Niu, Wenbin, Song, Wenyan, Jin, Haixia, Guo, Yihong, Dai, Shanjun, Hu, Linli, Fang, Lanlan, Wang, Qiujun, Li, Yuanyuan, Li, Wei, Na, Jie, Xie, Wei, Sun, Yingpu

“…Upon fertilization, drastic chromatin reorganization occurs during preimplantation development 1 . However, the global chromatin landscape and its molecular…”
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The impact of blastocyst grade on singleton birth weight in fresh IVF‒ET cycles in ART: a retrospective study by Shi, Senlin, Zhao, Boya, Hu, Zhan, Shi, Qiongyao

“…The positive correlation between embryo quality and pregnancy outcomes has been confirmed in many studies, but there are few on the impact of embryo quality on…”
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Sanghuangporus vaninii ethanol extract alleviates hyperuricemic renal injury by regulating the uric acid transporters and inhibiting HK-2 apoptosis by Hua, Liping, Zhang, Shuangshuang, Yang, Jiali, Zhou, Xiaoqi, Shi, Senlin

“…To investigate the acute toxicity of Sanghuangporus ethanol extract (SHEE) on ICR mice and the underlying mechanism of anti-hyperuricemic renal injury. ICR…”
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Increasing ovarian NAD+ levels improve mitochondrial functions and reverse ovarian aging by Yang, Qingling, Cong, Luping, Wang, Yujiao, Luo, Xiaoyan, Li, Hui, Wang, Huan, Zhu, Jing, Dai, Shanjun, Jin, Haixia, Yao, Guidong, Shi, Senlin, Hsueh, Aaron J., Sun, Yingpu

“…Loss of follicles together with decreased oocyte quality and quantity contribute to age-associated ovarian senescence and infertility. Although underlying…”
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Artificial neural network model- and response surface methodology-based optimization of Atractylodis Macrocephalae Rhizoma polysaccharide extraction, kinetic modelling and structural characterization by Qiu, Junjie, Shi, Menglin, Li, Siqi, Ying, Qianyi, Zhang, Xinxin, Mao, Xinxin, Shi, Senlin, Wu, Suxiang

“…[Display omitted] •The extraction conditions were optimized by three artificial neural network models and response surface methodology model.•The predictive…”
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Norcantharidin-Encapsulated C60-Modified Nanomicelles: A Potential Approach to Mitigate Cytotoxicity in Renal Cells and Simultaneously Enhance Anti-Tumor Activity in Hepatocellular Carcinoma Cells by Ding, Zhongpeng, Xu, Beihua, Zhang, Huimin, Wang, Zhenyu, Sun, Luying, Tang, Mengjie, Ding, Meihong, Zhang, Ting, Shi, Senlin

“…Objective: The objective of this study was to examine the preparation process of DSPE-PEG-C60/NCTD micelles and assess the impact of fullerenol (C60)-modified…”
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The Effect of Chinese Agarwood Essential Oil with Cyclodextrin Inclusion against PCPA-Induced Insomnia Rats by Lai, Yinfang, Hua, Liping, Yang, Jiali, Xu, Juewen, Chen, Junduo, Zhang, Shuangshuang, Zhu, Shunyao, Li, Jingjing, Shi, Senlin

“…To study the extraction process of agarwood active ingredients (AA) and investigate the safety and effectiveness of AA in the treatment of insomnia rats by…”
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Preparation and Evaluation of the Cytoprotective Activity of Micelles with DSPE-PEG-C60 as a Carrier Against Doxorubicin-Induced Cytotoxicity by Xu, Beihua, Ding, Zhongpeng, Hu, Ying, Zhang, Ting, Shi, Senlin, Yu, Guangmao, Qi, Xuchen

“…To deliver doxorubicin (DOX) with enhanced efficacy and safety , fullerenol-modified micelles were prepared with the amphiphilic polymer DSPE-PEG-C60 as a…”
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The Cytoprotective Effect of C60 Derivatives in the Self-Microemulsifying Drug Delivery System against Triptolide-Induced Cytotoxicity In Vitro by Xu, Beihua, Wang, Zhenyu, Zhang, Huimin, Xu, Xiao, Tang, Mengjie, Wang, Gang, Ding, Zhongpeng, Yu, Ruihao, Ding, Meihong, Zhang, Ting, Shi, Senlin

“…The aim of this study was to optimize the formulation of a C60-modified self-microemulsifying drug delivery system loaded with triptolide (C60-SMEDDS/TP) and…”
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Single-cell RNA sequencing of human oocytes reveals a differential transcriptomic profile associated with agar-like zona pellucida by Zhang, Xiangyang, Shi, Senlin, Wan, Ying, Song, Wenyan, Jin, Haixia, Sun, Yingpu

“…Agar-like zona pellucida (ZP) is the most common type of abnormal ZP, and is one of the causes of low fertility or infertility. However, the molecular…”
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Calcium Ionophore (A23187) Rescues the Activation of Unfertilized Oocytes After Intracytoplasmic Sperm Injection and Chromosome Analysis of Blastocyst After Activation by Xu, Ziwen, Yao, Guidong, Niu, Wenbin, Fan, Huiying, Ma, Xueshan, Shi, Senlin, Jin, Haixia, Song, Wenyan, Sun, Yingpu

“…Calcium is a crucial factor in regulating the biological behavior of cells. The imbalance of calcium homeostasis in cytoplasm will cause abnormal behavior of…”
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Preparation, Characterization, and Evaluation of Breviscapine Nanosuspension and Its Freeze-Dried Powder by Zhang, Ting, Li, Xixi, Xu, Juewen, Shao, Jingbao, Ding, Meihong, Shi, Senlin

“…As a biopharmaceutics classification system (BCS) class IV drug, breviscapine (Bre) has low solubility in water, poor chemical stability, a short biological…”
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Gene Spectrum and Clinical Traits of Nine Patients With Oocyte Maturation Arrest by Huo, Mingzhu, Zhang, Yile, Shi, Senlin, Shi, Hao, Liu, Yidong, Zhang, Lingyun, Wang, Yanchi, Niu, Wenbin

“…Oocyte maturation arrest is a disease that produces immature oocytes and cannot be mature after culturing , which leads to female primary infertility. We aimed…”
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Live births following preimplantation genetic testing for dynamic mutation diseases by karyomapping: a report of three cases by Shi, Dayuan, Xu, Jiawei, Niu, Wenbin, Liu, Yidong, Shi, Hao, Yao, Guidong, Shi, Senlin, Li, Gang, Song, Wenyan, Jin, Haixia, Sun, Yingpu

“…Purpose The preimplantation genetic testing for monogenic defects (PGT-M) is a beneficial strategy for the patients suffering from a Mendelian disease, which…”
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Combination immunotherapy of chlorogenic acid liposomes modified with sialic acid and PD-1 blockers effectively enhances the anti-tumor immune response and therapeutic effects by Li, Xixi, Zhu, Shunyao, Yin, Ping, Zhang, Shuangshuang, Xu, Juewen, Zhang, Qin, Shi, Senlin, Zhang, Ting

“…Melanoma is one of the most common malignant tumors. The anti-PD-1 antibody is used for the treatment of metastatic melanoma. Treatment success is only 35-40%…”
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Developmental potential of clinically discarded human embryos and associated chromosomal analysis by Yao, Guidong, Xu, Jiawei, Xin, Zhimin, Niu, Wenbin, Shi, Senlin, Jin, Haixia, Song, Wenyan, Wang, Enyin, Yang, Qingling, Chen, Lei, Sun, Yingpu

“…Clinically discarded human embryos, which are generated from both normal and abnormal fertilizations, have the potential of developing into blastocysts. A…”
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Glycoside scutellarin enhanced CD-MOF anchoring for laryngeal delivery by Zhao, Kena, Guo, Tao, Wang, Caifen, Zhou, Yong, Xiong, Ting, Wu, Li, Li, Xue, Mittal, Priyanka, Shi, Senlin, Gref, Ruxandra, Zhang, Jiwen

“…It is essential to develop new carriers for laryngeal drug delivery in light of the lack of therapy in laryngeal related diseases. When the inhalable…”
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The effect of sperm miR-34c on human embryonic development kinetics and clinical outcomes by Shi, Senlin, Shi, Qiongyao, Sun, Yingpu

“…We aimed to investigate the effect of sperm miR-34c on early human embryonic development kinetics and clinical outcomes of in vitro fertilization (IVF)…”
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Evaluation of brain-targeted trendence of scutellarin nasal administration by Shi, Senlin, Wu, Jinjin, Dai, Wenyun, Li, Changyu, Ge, Weihong

“…To evaluate the feasibility of developing brain-targeted nasal delivery system of scutellarin by the passage between nase and brain in nasal olfactory area…”
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