Search Results - "Shi, Ruona"

Loss of SPACA1 function causes autosomal recessive globozoospermia by damaging the acrosome–acroplaxome complex by Chen, Pingping, Saiyin, Hexige, Shi, Ruona, Liu, Bin, Han, Xu, Gao, Yuping, Ye, Xiantao, Zhang, Xiaofei, Sun, Yu

“…Abstract STUDY QUESTION Is the sperm acrosome membrane-associated protein 1 (SPACA1) gene critical to human globozoospermia? SUMMARY ANSWER The biallelic…”
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MARCH7-mediated ubiquitination decreases the solubility of ATG14 to inhibit autophagy by Shi, Xue, Wu, Wenfeng, Feng, Zhenhuan, Fan, Peiyang, Shi, Ruona, Zhang, Xiaofei

“…Autophagy is a fundamental biological process critical to all eukaryotic cellular life. Although autophagy has been increasingly studied, how its process is…”
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SS18 regulates pluripotent-somatic transition through phase separation by Kuang, Junqi, Zhai, Ziwei, Li, Pengli, Shi, Ruona, Guo, Wenjing, Yao, Yuxiang, Guo, Jing, Zhao, Guoqing, He, Jiangpin, Xu, Shuyang, Wu, Chuman, Yu, Shengyong, Zhou, Chunhua, Wu, Linlin, Qin, Yue, Cai, Baomei, Li, Wei, Wu, Zichao, Li, Xiaoxi, Chu, Shilong, Yang, Tingting, Wang, Bo, Cao, Shangtao, Li, Dongwei, Zhang, Xiaofei, Chen, Jiekai, Liu, Jing, Pei, Duanqing

“…The transition from pluripotent to somatic states marks a critical event in mammalian development, but remains largely unresolved. Here we report the…”
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Food-Derived Antioxidant Polysaccharides and Their Pharmacological Potential in Neurodegenerative Diseases by Li, Haifeng, Ding, Fei, Xiao, Lingyun, Shi, Ruona, Wang, Hongyu, Han, Wenjing, Huang, Zebo

“…Oxidative stress is known to impair architecture and function of cells, which may lead to various chronic diseases, and therefore therapeutic and nutritional…”
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Integrative Multi-omics Landscape of Non-structural Protein 3 of Severe Acute Respiratory Syndrome Coronaviruses by Shi, Ruona, Feng, Zhenhuan, Zhang, Xiaofei

“…The coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is currently a global pandemic…”
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SETDB1-Mediated Cell Fate Transition between 2C-Like and Pluripotent States by Wu, Kaixin, Liu, He, Wang, Yaofeng, He, Jiangping, Xu, Shuyang, Chen, Yaping, Kuang, Junqi, Liu, Jiadong, Guo, Lin, Li, Dongwei, Shi, Ruona, Shen, Li, Wang, Yangming, Zhang, Xiaofei, Wang, Jie, Pei, Duanqing, Chen, Jiekai

“…Known as a histone H3K9 methyltransferase, SETDB1 is essential for embryonic development and pluripotent inner cell mass (ICM) establishment. However, its…”
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Perturbation of METTL1-mediated tRNA N7- methylguanosine modification induces senescence and aging by Fu, Yudong, Jiang, Fan, Zhang, Xiao, Pan, Yingyi, Xu, Rui, Liang, Xiu, Wu, Xiaofen, Li, Xingqiang, Lin, Kaixuan, Shi, Ruona, Zhang, Xiaofei, Ferrandon, Dominique, Liu, Jing, Pei, Duanqing, Wang, Jie, Wang, Tao

“…Cellular senescence is characterized by a decrease in protein synthesis, although the underlying processes are mostly unclear. Chemical modifications to…”
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Physicochemical Characterization and Functional Analysis of the Polysaccharide from the Edible Microalga Nostoc sphaeroides by Li, Haifeng, Su, Linnan, Chen, Sheng, Zhao, Libin, Wang, Hongyu, Ding, Fei, Chen, Hong, Shi, Ruona, Wang, Yulan, Huang, Zebo

“…colonies have been used as food and medicine for centuries, and their main supporting matrix is polysaccharides, which help cells resist various environmental…”
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Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis by Zou, Qianxing, Yang, Lele, Shi, Ruona, Qi, Yuling, Zhang, Xiaofei, Qi, Huayu

“…Maintaining proteostasis is important for animal development. How proteostasis influences spermatogenesis that generates male gametes, spermatozoa, is not…”
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Identification of HLA-A11:01 and A02:01-Restricted EBV Peptides Using HLA Peptidomics by Wang, Yufei, Zhang, Wanlin, Shi, Ruona, Luo, Yanran, Feng, Zhenhuan, Chen, Yanhong, Zhang, Qiuting, Zhou, Yan, Liang, Jingtong, Ye, Xiaoping, Feng, Qisheng, Zhang, Xiaofei, Xu, Miao

“…Epstein-Barr Virus (EBV) is closely linked to nasopharyngeal carcinoma (NPC), notably prevalent in southern China. Although type II latency of EBV plays a…”
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SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation by Shi, Ruona, Shi, Xue, Qin, Dajiang, Tang, Shibing, Vermeulen, Michiel, Zhang, Xiaofei

“…Abstract Background Linear ubiquitination is a novel type of ubiquitination that plays important physiological roles in signalling pathways such as tumour…”
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H3K27ac mediated SS18/BAFs relocation regulates JUN induced pluripotent-somatic transition by Lin, Runxia, Zhai, Ziwei, Kuang, Junqi, Wu, Chuman, Yao, Yuxiang, Shi, Ruona, He, Jiangping, Xu, Shuyang, Li, Pengli, Fan, Yixin, Li, Wei, Wu, Zichao, Li, Xiaoxi, Ming, Jin, Guo, Jing, Wang, Bo, Li, Dongwei, Cao, Shangtao, Zhang, Xiaofei, Li, Yi, Pei, Duanqing, Liu, Jing

“…Abstract Background The exit from pluripotency or pluripotent-somatic transition (PST) landmarks an event of early mammalian embryonic development,…”
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Antioxidant and neuroprotective effects of Dictyophora indusiata polysaccharide in Caenorhabditis elegans by Zhang, Ju, Shi, Ruona, Li, Haifeng, Xiang, Yanxia, Xiao, Lingyun, Hu, Minghua, Ma, Fangli, Ma, Chung Wah, Huang, Zebo

“…Dictyophora indusiata is a medicinal mushroom traditionally used in China for a variety of conditions, including inflammatory and neural diseases. D. indusiata…”
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The human disease-associated gene ZNFX1 controls inflammation through inhibition of the NLRP3 inflammasome by Huang, Jing, Wang, Yao, Jia, Xin, Zhao, Changfeng, Zhang, Meiqi, Bao, Mi, Fu, Pan, Cheng, Cuiqin, Shi, Ruona, Zhang, Xiaofei, Cui, Jun, Wan, Gang, Xu, Anlong

“…Inherited deficiency of zinc finger NFX1-type containing 1 (ZNFX1), a dsRNA virus sensor, is associated with severe familial immunodeficiency, multisystem…”
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YTHDF1 facilitates PRC1‐mediated H2AK119ub in human ES cells by Zhang, Jingyuan, Wang, Tianyu, Shi, Ruona, Zhao, Yuan, Zhang, Yanqi, Zhang, Cong, Xing, Qi, Zhou, Tiancheng, Shan, Yongli, Yao, Hongjie, Zhang, Xiaofei, Pan, Guangjin

“…Polycomb repressive complexes (PRCs) play critical roles in cell fate decisions during normal development as well as disease progression through mediating…”
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HERD-1 mediates multiphase condensate immiscibility to regulate small RNA-driven transgenerational epigenetic inheritance by Zhao, Changfeng, Cai, Shiyu, Shi, Ruona, Li, Xinru, Deng, Boyuan, Li, Ruofei, Yang, Shuhan, Huang, Jing, Liang, Yonglin, Lu, Pu, Yuan, Zhongping, Jia, Haoxiang, Jiang, Zongjin, Zhang, Xiaofei, Kennedy, Scott, Wan, Gang

“…Biomolecular condensates, such as the nucleolus, stress granules/processing bodies and germ granules, are multiphase assemblages whose formation mechanisms and…”
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Tanshinone IIA Inhibits Glutamate-Induced Oxidative Toxicity through Prevention of Mitochondrial Dysfunction and Suppression of MAPK Activation in SH-SY5Y Human Neuroblastoma Cells by Huang, Zebo, Shi, Ruona, Xiao, Lingyun, Ding, Fei, Wang, Hongyu, Han, Wenjing, Li, Haifeng, Ai, Liping

“…Glutamate excitotoxicity is associated with many neurological diseases, including cerebral ischemia and neurodegenerative diseases. Tanshinone IIA, a…”
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A primate-specific endogenous retroviral envelope protein sequesters SFRP2 to regulate human cardiomyocyte development by Zhang, Ran, Wu, Menghua, Xiang, Dan, Zhu, Jieying, Zhang, Qi, Zhong, Hui, Peng, Yuling, Wang, Zhenhua, Ma, Gang, Li, Guihuan, Liu, Fengping, Ye, Weipeng, Shi, Ruona, Zhou, Xuemeng, Babarinde, Isaac A, Su, Huanxing, Chen, Jiekai, Zhang, Xiaofei, Qin, Dajiang, Hutchins, Andrew P, Pei, Duanqing, Li, Dongwei

“…Endogenous retroviruses (ERVs) occupy a significant part of the human genome, with some encoding proteins that influence the immune system or regulate…”
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Astragalus Polysaccharide Suppresses 6-Hydroxydopamine-Induced Neurotoxicity in Caenorhabditis elegans by Huang, Zebo, Ma, Chung Wah, Ma, Fangli, Han, Wenjing, Wang, Hongyu, Ding, Fei, Shi, Ruona, Li, Haifeng, Hu, Minghua

“…Astragalus membranaceus is a medicinal plant traditionally used in China for a variety of conditions, including inflammatory and neural diseases. Astragalus…”
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SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation by Shi, Ruona, Shi, Xue, Qin, Dajiang, Tang, Shibing, Vermeulen, Michiel, Zhang, Xiaofei

“…Linear ubiquitination is a novel type of ubiquitination that plays important physiological roles in signalling pathways such as tumour necrosis factor (TNF)…”
Get full text