Search Results - "Shi, Rubing"

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  1. 1

    Stroke subtype-dependent synapse elimination by reactive gliosis in mice by Shi, Xiaojing, Luo, Longlong, Wang, Jixian, Shen, Hui, Li, Yongfang, Mamtilahun, Muyassar, Liu, Chang, Shi, Rubing, Lee, Joon-Hyuk, Tian, Hengli, Zhang, Zhijun, Wang, Yongting, Chung, Won-Suk, Tang, Yaohui, Yang, Guo-Yuan

    Published in Nature communications (26-11-2021)
    “…The pathological role of reactive gliosis in CNS repair remains controversial. In this study, using murine ischemic and hemorrhagic stroke models, we…”
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    Journal Article
  2. 2

    Microglia exacerbate white matter injury via complement C3/C3aR pathway after hypoperfusion by Zhang, Lin-Yuan, Pan, Jiaji, Mamtilahun, Muyassar, Zhu, Yuan, Wang, Liping, Venkatesh, Ashwin, Shi, Rubing, Tu, Xuanqiang, Jin, Kunlin, Wang, Yongting, Zhang, Zhijun, Yang, Guo-Yuan

    Published in Theranostics (2020)
    “…Microglial activation participates in white matter injury after cerebral hypoperfusion. However, the underlying mechanism is unclear. Here, we explore whether…”
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    Journal Article
  3. 3

    Endothelial progenitor cell transplantation alleviated ischemic brain injury via inhibiting C3/C3aR pathway in mice by Ma, Yuanyuan, Jiang, Lu, Wang, Liping, Li, Yongfang, Liu, Yanqun, Lu, Wenjing, Shi, Rubing, Zhang, Linyuan, Fu, Zongjie, Qu, Meijie, Liu, Yingling, Wang, Yongting, Zhang, Zhijun, Yang, Guo-Yuan

    “…Endothelial progenitor cell transplantation is a potential therapeutic approach in brain ischemia. However, whether the therapeutic effect of endothelial…”
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    BK Channel-Mediated Microglial Phagocytosis Alleviates Neurological Deficit After Ischemic Stroke by Huang, Shuxian, Chen, Tingting, Suo, Qian, Shi, Rubing, Khan, Haroon, Ma, Yuanyuan, Tang, Yaohui, Yang, Guo-Yuan, Zhang, Zhijun

    Published in Frontiers in cellular neuroscience (01-07-2021)
    “…Microglial phagocytosis benefits neurological recovery after stroke. Large-conductance Ca2 + -activated K + currents are expressed in activated microglia, and…”
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    Journal Article
  7. 7

    Fingolimod Inhibits Inflammation but Exacerbates Brain Edema in the Acute Phases of Cerebral Ischemia in Diabetic Mice by Li, Wanlu, He, Tingting, Jiang, Lu, Shi, Rubing, Song, Yaying, Mamtilahun, Muyassar, Ma, Yuanyuan, Zhang, Zhijun, Tang, Yaohui, Yang, Guo-Yuan, Wang, Yongting

    Published in Frontiers in neuroscience (11-08-2020)
    “…Background and Purpose: Diabetes mellitus increases stroke incidence and mortality and hampers functional recovery after stroke. Fingolimod has been shown to…”
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    Journal Article
  8. 8

    Advanced rehabilitation in ischaemic stroke research by Wang, Jixian, Li, Yongfang, Qi, Lin, Mamtilahun, Muyassar, Liu, Chang, Liu, Ze, Shi, Rubing, Wu, Shengju, Yang, Guo-Yuan

    Published in Stroke and vascular neurology (01-08-2024)
    “…At present, due to the rapid progress of treatment technology in the acute phase of ischaemic stroke, the mortality of patients has been greatly reduced but…”
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    Journal Article
  9. 9

    ApoE-Dependent Protective Effects of Sesamol on High-Fat Diet-Induced Behavioral Disorders: Regulation of the Microbiome-Gut–Brain Axis by Yuan, Tian, Chu, Chuanqi, Shi, Rubing, Cui, Tianlin, Zhang, Xinglin, Zhao, Yihang, Shi, Xu, Hui, Yan, Pan, Junru, Qian, Rui, Dai, Xiaoshuang, Liu, Zhigang, Liu, Xuebo

    Published in Journal of agricultural and food chemistry (05-06-2019)
    “…Sesamol, an antioxidant lignan from sesame oil, possesses neuroprotective bioactivities. The present work was aimed to elucidate the systemic protective…”
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    Journal Article
  10. 10

    M2 Microglia Extracellular Vesicle miR-124 Regulates Neural Stem Cell Differentiation in Ischemic Stroke via AAK1/NOTCH by Song, Yaying, Shi, Rubing, Liu, Yingjun, Cui, Fengzhen, Han, Lu, Wang, Chuandong, Chen, Tingting, Li, Zongwei, Zhang, Zhijun, Tang, Yaohui, Yang, Guo-Yuan, Guan, Yangtai

    Published in Stroke (1970) (01-10-2023)
    “…BACKGROUND: Small extracellular vesicles (sEVs) derived from M2 microglia (M2-microglia–derived small extracellular vesicles [M2-sEVs]) contribute to central…”
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    Journal Article
  11. 11

    Blocking C3d + /GFAP + A1 Astrocyte Conversion with Semaglutide Attenuates Blood-Brain Barrier Disruption in Mice after Ischemic Stroke by Zhang, Qi, Liu, Chang, Shi, Rubing, Zhou, Shiyi, Shan, Huimin, Deng, Lidong, Chen, Tingting, Guo, Yiyan, Zhang, Zhijun, Yang, Guo-Yuan, Wang, Yongting, Tang, Yaohui

    Published in Aging and disease (01-06-2022)
    “…Astrocytes play an essential role in the modulation of blood-brain barrier function. Neurological diseases induce the transformation of astrocytes into a…”
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    Journal Article
  12. 12

    Progranulin released from microglial lysosomes reduces neuronal ferroptosis after cerebral ischemia in mice by Chen, Tingting, Shi, Rubing, Suo, Qian, Wu, Shengju, Liu, Chang, Huang, Shuxian, Haroon, Khan, Liu, Ze, He, Yuyan, Tian, Heng-Li, Wang, Yongting, Tang, Yaohui, Yang, Guo-Yuan, Zhang, Zhijun

    “…The cellular redox state is essential for inhibiting ferroptosis. Progranulin (PGRN) plays an important role in maintaining the cellular redox state after…”
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  13. 13

    Oligodendrocyte Precursor Cells Transplantation Improves Stroke Recovery via Oligodendrogenesis, Neurite Growth and Synaptogenesis by Li, Wanlu, He, Tingting, Shi, Rubing, Song, Yaying, Wang, Liping, Zhang, Zhijun, Tang, Yaohui, Yang, Guo-Yuan, Wang, Yongting

    Published in Aging and disease (01-12-2021)
    “…Ischemic-induced white matter injury is strongly correlated with the poor neurological outcomes in stroke patients. The transplantation of oligodendrocyte…”
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    Journal Article
  14. 14

    Hypoxanthine is a metabolic biomarker for inducing GSDME-dependent pyroptosis of endothelial cells during ischemic stroke by Ye, Jing, Bi, Xinyuan, Deng, Shiyu, Wang, Xianghui, Liu, Ze, Suo, Qian, Wu, Jiao, Chen, Haoran, Wang, Yong, Qian, Kun, Shi, Rubing, Zhao, Jing, Yang, Guo-Yuan, Ye, Jian, Tang, Yaohui

    Published in Theranostics (01-01-2024)
    “…Stroke induces metabolic changes in the body, and metabolites have become potential biomarkers for stroke. However, the specific metabolites involved in stroke…”
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  15. 15

    Tropism-shifted AAV-PHP.eB-mediated bFGF gene therapy promotes varied neurorestoration after ischemic stroke in mice by Shi, Rubing, Ye, Jing, Liu, Ze, Wang, Cheng, Wu, Shengju, Shen, Hui, Suo, Qian, Li, Wanlu, He, Xiaosong, Zhang, Zhijun, Tang, Yaohui, Yang, Guo-Yuan, Wang, Yongting

    Published in Neural regeneration research (10-07-2024)
    “…AAV-PHP.eB is an artificial adeno-associated virus (AAV) that crosses the blood-brain barrier and targets neurons more efficiently than other AAVs when…”
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  16. 16

    Blocking C3[d.sup.+]/GFA[P.sup.+] A1 Astrocyte Conversion with Semaglutide Attenuates Blood-Brain Barrier Disruption in Mice after Ischemic Stroke by Zhang, Qi, Liu, Chang, Shi, Rubing, Zhou, Shiyi, Shan, Huimin, Deng, Lidong, Chen, Tingting, Guo, Yiyan, Zhang, Zhijun, Yang, Guo-Yuan, Wang, Yongting, Tang, Yaohui

    Published in Aging and disease (01-06-2022)
    “…Astrocytes play an essential role in the modulation of blood-brain barrier function. Neurological diseases induce the transformation of astrocytes into a…”
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    Journal Article
  17. 17