Search Results - "Shi, Qiaofa"
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Resistin induces multidrug resistance in myeloma by inhibiting cell death and upregulating ABC transporter expression
Published in Haematologica (Roma) (01-07-2017)“…Despite advances in therapy, multiple myeloma remains incurable, with a high frequency of relapse. This suggests the need to identify additional factors that…”
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Tumor-Targeted Gene Silencing IDO Synergizes PTT-Induced Apoptosis and Enhances Anti-tumor Immunity
Published in Frontiers in immunology (09-06-2020)“…Photothermal therapy (PTT) has been demonstrated to be a promising cancer treatment approach because it can be modulated to induce apoptosis instead of…”
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CVB3 VP1 interacts with MAT1 to inhibit cell proliferation by interfering with Cdk-activating kinase complex activity in CVB3-induced acute pancreatitis
Published in PLoS pathogens (01-02-2021)“…Coxsackievirus B3 (CVB3) belongs to the genus Enterovirus of the family Picornaviridae and can cause acute acinar pancreatitis in adults. However, the…”
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Increased TLR4 Expression Aggravates Sepsis by Promoting IFN-γ Expression in CD38−/− Mice
Published in Journal of immunology research (2019)“…Gram-negative bacterial sepsis accounts for up to 50% worldwide sepsis that causes hospital mortality. Acute kidney injury (AKI), a common complication of…”
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Curcumin attenuates collagen-induced rat arthritis via anti-inflammatory and apoptotic effects
Published in International immunopharmacology (01-07-2019)“…Curcumin is a natural herbal product that has been popularly used to treat autoimmune diseases in China; however, its effects on rheumatoid arthritis and its…”
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Icariin ameliorates Coxsackievirus B3-induced viral myocarditis by modulating the S100 calcium binding protein A6/β-catenin/c-Myc signaling pathway
Published in Phytomedicine (Stuttgart) (01-12-2024)“…•ICA reduces CVB3 replication in vitro and in vivo;•ICA inhibits the S100A6/β-catenin/c-Myc signal pathway to attenuate CVB3-induced cardiomyocyte…”
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MicroRNA-519d-3p Inhibits Proliferation and Promotes Apoptosis by Targeting HIF-2α in Cervical Cancer Under Hypoxic Conditions
Published in Oncology research (23-08-2018)“…HIF-2α knockdown inhibits proliferation, arrests the cell cycle, and promotes apoptosis and autophagy under hypoxic conditions in cervical cancer. However, the…”
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A new cancer immunotherapy via simultaneous DC‐mobilization and DC‐targeted IDO gene silencing using an immune‐stimulatory nanosystem
Published in International journal of cancer (15-10-2018)“…The activity of negative immune regulatory molecules, such as indoleamine 2,3‐oxygenase (IDO), significantly attenuates DC (Dendritic cells)‐mediated…”
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The Improvement of Immune Effect of Recombinant Human Beta-Defensin 2 on Hepatitis B Vaccine in Mice
Published in Viral immunology (01-03-2021)“…Immunization with hepatitis B vaccine is an effective measure for prevention and control of hepatitis B Virus (HBV) infection. Although lots of efforts to…”
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miR‑519d‑3p/HIF‑2α axis increases the chemosensitivity of human cervical cancer cells to cisplatin via inactivation of PI3K/AKT signaling
Published in Molecular medicine reports (01-05-2021)“…Cisplatin (DDP)‑based chemotherapy is a standard treatment for cervical cancer, although chemotherapy resistance remains a major concern. Hypoxia‑inducible…”
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miR-519d-3p/HIF-2[alpha] axis increases the chemosensitivity of human cervical cancer cells to cisplatin via inactivation of PI3K/AKT signaling
Published in Molecular medicine reports (01-05-2021)“…Cisplatin (DDP)-based chemotherapy is a standard treatment for cervical cancer, although chemotherapy resistance remains a major concern. Hypoxia-inducible…”
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Similarity in the functions of HIF-1α and HIF-2α proteins in cervical cancer cells
Published in Oncology letters (01-11-2017)“…Hypoxia is a common feature of many solid tumours, including cervical cancer. Aggressive tumour progression is mostly associated with hypoxia. Furthermore,…”
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Targeted-gene silencing of BRAF to interrupt BRAF/MEK/ERK pathway synergized photothermal therapeutics for melanoma using a novel FA-GNR-siBRAF nanosystem
Published in Nanomedicine (01-07-2018)“…Melanoma is significantly associated with mutant BRAF gene, a suitable target for siRNA-based anti-melanoma therapy. However, a tumor-specific delivery system…”
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Resistin Induces Multidrug Resistance in Myeloma By Inhibiting Cell Death and Upregulating ABC Transporter Expression
Published in Blood (02-12-2016)“…Chemoresistance is a major hurdle in multiple myeloma. Most patients are prone to develop resistance to a wide spectrum of anticancer agents, significantly…”
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Similarity in the functions of HIF-1[alpha] and HIF-2[alpha] proteins in cervical cancer cells
Published in Oncology letters (01-11-2017)“…Hypoxia is a common feature of many solid tumours, including cervical cancer. Aggressive tumour progression is mostly associated with hypoxia. Furthermore,…”
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A novel GNRs-PEI/GNRs-PEI-folate for efficiently delivering siRNA
Published in Technology and health care (08-12-2015)“…RNA interference (RNAi) employs double-stranded RNA or siRNA (small interfering RNA) to silence gene expression in cells. The widespread use of RNAi…”
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Construction of eukaryotic expressing plasmids encoding HA and HA1 of influenza A virus and their transient expression in HEK293 cells
Published in Journal of Huazhong University of Science and Technology. Medical sciences (2006)“…In order to explore the feasibility and protective efficiency of influenza DNA vaccine, we constructed eukaryotic expressing plasmids encoding HA and HA1 of…”
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