Search Results - "Shi, Kaibin"

Dissemination of brain inflammation in traumatic brain injury by Shi, Kaibin, Zhang, Jianning, Dong, Jing-fei, Shi, Fu-Dong

“…Traumatic brain injury (TBI) is recognized as a global health problem due to its increasing occurrence, challenging treatment, and persistent impacts on brain…”
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IL (Interleukin)-15 Bridges Astrocyte-Microglia Crosstalk and Exacerbates Brain Injury Following Intracerebral Hemorrhage by Shi, Samuel X., Li, Yu-Jing, Shi, Kaibin, Wood, Kristofer, Ducruet, Andrew F., Liu, Qiang

“…BACKGROUND AND PURPOSE—Microglia are among the first cells to respond to intracerebral hemorrhage (ICH), but the mechanisms that underlie their activity…”
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Chronic inflammation, cognitive impairment, and distal brain region alteration following intracerebral hemorrhage by Shi, Elaine, Shi, Kaibin, Qiu, Shenfeng, Sheth, Kevin N., Lawton, Michael T., Ducruet, Andrew F.

“…ABSTRACT Delayed cognitive decline commonly occurs following intracerebral hemorrhage (ICH), but the mechanisms underlying this phenomenon remain obscure. We…”
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Brain Ischemia Suppresses Immunity in the Periphery and Brain via Different Neurogenic Innervations by Liu, Qiang, Jin, Wei-Na, Liu, Yaou, Shi, Kaibin, Sun, Haoran, Zhang, Fang, Zhang, Chao, Gonzales, Rayna J., Sheth, Kevin N., La Cava, Antonio, Shi, Fu-Dong

“…Brain ischemia inhibits immune function systemically, with resulting infectious complications. Whether in stroke different immune alterations occur in brain…”
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Fingolimod enhances the efficacy of delayed alteplase administration in acute ischemic stroke by promoting anterograde reperfusion and retrograde collateral flow by Tian, De‐Cai, Shi, Kaibin, Zhu, Zilong, Yao, Jia, Yang, Xiaoxia, Su, Lei, Zhang, Sheng, Zhang, Meixia, Gonzales, Rayna J., Liu, Qiang, Huang, DeRen, Waters, Michael F., Sheth, Kevin N., Ducruet, Andrew F., Fu, Ying, Lou, Min, Shi, Fu‐Dong

“…Objective The present study was undertaken to determine the efficacy of coadministration of fingolimod with alteplase in acute ischemic stroke patients in a…”
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Organ‐ and cell‐specific immune responses are associated with the outcomes of intracerebral hemorrhage by Zhang, Jing, Shi, Kaibin, Li, Zhiguo, Li, Minshu, Han, Yujuan, Wang, Lei, Zhang, Zhecheng, Yu, Changlu, Zhang, Fang, Song, Lijuan, Dong, Jing‐Fei, Cava, Antonio La, Sheth, Kevin N., Shi, Fu‐Dong

“…Severe brain injury significantly influences immune responses; however, the levels at which this influence occurs and which neurogenic pathways are involved…”
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Editorial: Brain injury associated secondary injury and remote organ injury by Tang, Lujia, Shi, Kaibin, Zhang, Yanjun, Fu, Ying, Gao, Jie, Zhao, Zilong

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Neuroblast senescence in the aged brain augments natural killer cell cytotoxicity leading to impaired neurogenesis and cognition by Jin, Wei-Na, Shi, Kaibin, He, Wenyan, Sun, Jun-Hong, Van Kaer, Luc, Shi, Fu-Dong, Liu, Qiang

“…Normal aging is accompanied by escalating systemic inflammation. Yet the potential impact of immune homeostasis on neurogenesis and cognitive decline during…”
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Bidirectional degeneration in the visual pathway in neuromyelitis optica spectrum disorder (NMOSD) by Tian, De-Cai, Su, Lei, Fan, Moli, Yang, Jian, Zhang, Rui, Wen, Peng, Han, Yujuan, Yu, Changlu, Zhang, Chao, Ren, Honglei, Shi, Kaibin, Zhu, Zilong, Dong, Yinhua, Liu, Yaou, Shi, Fu-Dong

“…Objective: This study aims to investigate whether bidirectional degeneration occurs within the visual pathway and, if so, the extent of such changes in…”
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Dimethyl Fumarate and Monomethyl Fumarate Promote Post-Ischemic Recovery in Mice by Yao, Yang, Miao, Weimin, Liu, Zhijia, Han, Wei, Shi, Kaibin, Shen, Yi, Li, Handong, Liu, Qiang, Fu, Ying, Huang, DeRen, Shi, Fu-Dong

“…Oxidative stress plays an important role in cerebral ischemia–reperfusion injury. Dimethyl fumarate (DMF) and its primary metabolite monomethyl fumarate (MMF)…”
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Histidine-rich glycoprotein modulates neutrophils and thrombolysis-associated hemorrhagic transformation by Jiang, Wei, Zhao, Yuexin, Liu, Rongrong, Zhang, Bohao, Xie, Yuhan, Gao, Bin, Shi, Kaibin, Zou, Ming, Jia, Dongmei, Ding, Jiayue, Hu, Xiaowei, Duan, Yanli, Han, Ranran, Huang, DeRen, Van Kaer, Luc, Shi, Fu-Dong

“…Intravenous thrombolysis using recombinant tissue plasminogen activator (tPA) remains the primary treatment for patients with acute ischemic stroke (AIS)…”
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Autoantibody to MOG suggests two distinct clinical subtypes of NMOSD by Yan, Yaping, Li, Yujing, Fu, Ying, Yang, Li, Su, Lei, Shi, Kaibin, Li, Minshu, Liu, Qiang, Borazanci, Aimee, Liu, Yaou, He, Yong, Bennett, Jeffrey L., Vollmer, Timothy L., Shi, Fu-Dong

“…We characterized a unique group of patients with neuromyelitis optica spectrum disorder （NMOSD） who carded autoantibod- ies of aquaporin-4 （AQP4） and…”
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White matter disease derived from vascular and demyelinating origins by Zhang, Lin-Jie, Tian, De-Cai, Yang, Li, Shi, Kaibin, Liu, Yaou, Wang, Yilong, Shi, Fu-Dong

“…Damage or microstructural alterations of the white matter can cause dysfunction of the intrinsic neural networks in a condition termed as white matter disease…”
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Cortical Thinning and Ventricle Enlargement in Neuromyelitis Optica Spectrum Disorders by Tian, De-Cai, Xiu, Yuwen, Wang, Xinli, Shi, Kaibin, Fan, Moli, Li, Ting, Li, Huining, Su, Lei, Ma, Yuetao, Xu, Wangshu, Song, Tian, Liu, Yaou, Shi, Fu-Dong, Zhang, Xinghu

“…Background: In neuromyelitis optica spectrum disorders (NMOSDs), inflammation is not the sole driver of accumulation of disability; neurodegeneration is…”
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Abstract 98: Brain-Derived Programmed Death-Ligand 1 Induces Post-Stroke Immunosuppression by Cheng, Nuo, Wang, Hong, Shi, Kaibin

“…Background and purposePost-stroke immunosuppression is associated with increased infection risk and mortality of stroke patients. However, the mechanisms…”
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Primary Central Nervous System Lymphoma With Symmetrical Pyramidal Tract Hyperintensity by Shi, Kaibin, Shen, Junlin, Yue, Xuanye

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Global brain inflammation in stroke by Shi, Kaibin, Tian, De-Cai, Li, Zhi-Guo, Ducruet, Andrew F, Lawton, Michael T, Shi, Fu-Dong

“…Stroke, including acute ischaemic stroke and intracerebral haemorrhage, results in neuronal cell death and the release of factors such as damage-associated…”
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Neurovascular Inflammation and Complications of Thrombolysis Therapy in Stroke by Liu, Qiang, Shi, Kaibin, Wang, Yongjun, Shi, Fu-Dong

“…Intravenous thrombolysis via tPA (tissue-type plasminogen activator) is the only approved pharmacological treatment for acute ischemic stroke, but its benefits…”
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Identifying Physiological Predictors of the Solumedrol-Resistant Multiple Sclerosis Relapse and its Clinical Repercussions (P3.2-089) by Roy, Dolly, Shi, Kaibin, Shi, Fu-Dong

“…Abstract only…”
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tPA Mobilizes Immune Cells That Exacerbate Hemorrhagic Transformation in Stroke by Shi, Kaibin, Zou, Ming, Jia, Dong-Mei, Shi, Samuel, Yang, Xiaoxia, Liu, Qiang, Dong, Jing-fei, Sheth, Kevin N., Wang, Xiaoying, Shi, Fu-Dong

“…Hemorrhagic complications represent a major limitation of intravenous thrombolysis using tPA (tissue-type plasminogen activator) in patients with ischemic…”
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