Search Results - "Shi, Junwei"

The Mechanisms behind the Therapeutic Activity of BET Bromodomain Inhibition by Shi, Junwei, Vakoc, Christopher R.

“…The bromodomain and extraterminal (BET) protein Brd4 recruits transcriptional regulatory complexes to acetylated chromatin. While Brd4 is considered to be a…”
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Switching p-type to high-performance n-type organic electrochemical transistors via doped state engineering by Li, Peiyun, Shi, Junwei, Lei, Yuqiu, Huang, Zhen, Lei, Ting

“…High-performance n-type organic electrochemical transistors (OECTs) are essential for logic circuits and sensors. However, the performances of n-type OECTs lag…”
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Discovery of cancer drug targets by CRISPR-Cas9 screening of protein domains by Shi, Junwei, Wang, Eric, Milazzo, Joseph P, Wang, Zihua, Kinney, Justin B, Vakoc, Christopher R

“…Cancer drug targets are identified by CRISPR-based screens that knock out functional protein domains. CRISPR-Cas9 genome editing technology holds great promise…”
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ALC1 links chromatin accessibility to PARP inhibitor response in homologous recombination-deficient cells by Verma, Priyanka, Zhou, Yeqiao, Cao, Zhendong, Deraska, Peter V., Deb, Moniher, Arai, Eri, Li, Weihua, Shao, Yue, Puentes, Laura, Li, Yiwen, Patankar, Sonali, Mach, Robert H., Faryabi, Robert B., Shi, Junwei, Greenberg, Roger A.

“…The response to poly(ADP-ribose) polymerase inhibitors (PARPi) is dictated by homologous recombination (HR) DNA repair and the abundance of lesions that trap…”
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Cellulose-based sensors for metal ions detection by Fan, Jiang, Zhang, Sufeng, Li, Fei, Shi, Junwei

“…Cellulose-based materials can be used as chemical sensors for efficiently detecting metal ions in environmental applications because of their low price,…”
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High-performance CRISPR-Cas12a genome editing for combinatorial genetic screening by Gier, Rodrigo A., Budinich, Krista A., Evitt, Niklaus H., Cao, Zhendong, Freilich, Elizabeth S., Chen, Qingzhou, Qi, Jun, Lan, Yemin, Kohli, Rahul M., Shi, Junwei

“…CRISPR-based genetic screening has revolutionized cancer drug target discovery, yet reliable, multiplex gene editing to reveal synergies between gene targets…”
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Roles of arabidopsis WRKY18, WRKY40 and WRKY60 transcription factors in plant responses to abscisic acid and abiotic stress by Chen, Han, Lai, Zhibing, Shi, Junwei, Xiao, Yong, Chen, Zhixiang, Xu, Xinping

“…WRKY transcription factors are involved in plant responses to both biotic and abiotic stresses. Arabidopsis WRKY18, WRKY40, and WRKY60 transcription factors…”
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In Situ Ligand Bonding Management of CsPbI3 Perovskite Quantum Dots Enables High‐Performance Photovoltaics and Red Light‐Emitting Diodes by Shi, Junwei, Li, Fangchao, Jin, Yan, Liu, Cheng, Cohen‐Kleinstein, Ben, Yuan, Shuai, Li, Youyong, Wang, Zhao‐Kui, Yuan, Jianyu, Ma, Wanli

“…To fine‐tune surface ligands towards high‐performance devices, we developed an in situ passivation process for all‐inorganic cesium lead iodide (CsPbI3)…”
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Time series prediction model using LSTM-Transformer neural network for mine water inflow by Shi, Junwei, Wang, Shiqi, Qu, Pengfei, Shao, Jianli

“…Mine flooding accidents have occurred frequently in recent years, and the predicting of mine water inflow is one of the most crucial flood warning indicators…”
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14.1% CsPbI3 Perovskite Quantum Dot Solar Cells via Cesium Cation Passivation by Ling, Xufeng, Zhou, Sijie, Yuan, Jianyu, Shi, Junwei, Qian, Yuli, Larson, Bryon W., Zhao, Qian, Qin, Chaochao, Li, Fangchao, Shi, Guozheng, Stewart, Connor, Hu, Jiaxin, Zhang, Xuliang, Luther, Joseph M., Duhm, Steffen, Ma, Wanli

“…Surface manipulation of quantum dots (QDs) has been extensively reported to be crucial to their performance when applied into optoelectronic devices,…”
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Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells by Grevet, Jeremy D, Lan, Xianjiang, Hamagami, Nicole, Edwards, Christopher R, Sankaranarayanan, Laavanya, Ji, Xinjun, Bhardwaj, Saurabh K, Face, Carolyne J, Posocco, David F, Abdulmalik, Osheiza, Keller, Cheryl A, Giardine, Belinda, Sidoli, Simone, Garcia, Ben A, Chou, Stella T, Liebhaber, Stephen A, Hardison, Ross C, Shi, Junwei, Blobel, Gerd A

“…Increasing fetal hemoglobin (HbF) levels in adult red blood cells provides clinical benefit to patients with sickle cell disease and some forms of…”
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POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer by Huang, Yu-Han, Klingbeil, Olaf, He, Xue-Yan, Wu, Xiaoli S, Arun, Gayatri, Lu, Bin, Somerville, Tim D D, Milazzo, Joseph P, Wilkinson, John E, Demerdash, Osama E, Spector, David L, Egeblad, Mikala, Shi, Junwei, Vakoc, Christopher R

“…Small cell lung cancer (SCLC) is widely considered to be a tumor of pulmonary neuroendocrine cells; however, a variant form of this disease has been described…”
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Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma by Brien, Gerard L, Remillard, David, Shi, Junwei, Hemming, Matthew L, Chabon, Jonathon, Wynne, Kieran, Dillon, Eugène T, Cagney, Gerard, Van Mierlo, Guido, Baltissen, Marijke P, Vermeulen, Michiel, Qi, Jun, Fröhling, Stefan, Gray, Nathanael S, Bradner, James E, Vakoc, Christopher R, Armstrong, Scott A

“…Synovial sarcoma tumours contain a characteristic fusion protein, SS18-SSX, which drives disease development. Targeting oncogenic fusion proteins presents an…”
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Guanidinium‐Assisted Surface Matrix Engineering for Highly Efficient Perovskite Quantum Dot Photovoltaics by Ling, Xufeng, Yuan, Jianyu, Zhang, Xuliang, Qian, Yuli, Zakeeruddin, Shaik M., Larson, Bryon W., Zhao, Qian, Shi, Junwei, Yang, Jiacheng, Ji, Kang, Zhang, Yannan, Wang, Yongjie, Zhang, Chunyang, Duhm, Steffen, Luther, Joseph M., Grätzel, Michael, Ma, Wanli

“…Metal halide perovskite quantum dots (Pe‐QDs) are of great interest in new‐generation photovoltaics (PVs). However, it remains challenging in the construction…”
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Assembly dynamics of a large space modular satellite antenna by Li, Ke, Tian, Qiang, Shi, Junwei, Liu, Dali

“…•A novel computation and optimization methodology is proposed for studying a space antenna assembly dynamics.•An efficient particle swarm optimization…”
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An AIEgen-based fluorescent probe for highly selective and specific imaging of lipid droplets in L02 and HepG2 cells by Shi, Junwei, Tian, Yong, Guo, Bingpeng, Wu, Yulong, Jing, Jing, Zhang, Rubo, Zhang, Xiaoling

“…•The probe has AIE performance. (ΦF(liq) = 0.1% ; ΦF(sol) = 17.9%).•The probe could highly selective, specific imaging LDs in L02 and HepG2 cells.•The probe…”
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BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells by Yao, Chen, Lou, Guohua, Sun, Hong-Wei, Zhu, Ziang, Sun, Yi, Chen, Zeyu, Chauss, Daniel, Moseman, E. Ashley, Cheng, Jun, D’Antonio, Marc A., Shi, Wangke, Shi, Junwei, Kometani, Kohei, Kurosaki, Tomohiro, Wherry, E. John, Afzali, Behdad, Gattinoni, Luca, Zhu, Yuwen, McGavern, Dorian B., O’Shea, John J., Schwartzberg, Pamela L., Wu, Tuoqi

“…During chronic infection and cancer, a self-renewing CD8 + T cell subset maintains long-term immunity and is critical to the effectiveness of immunotherapy…”
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Sensitivity analysis of deployable flexible space structures with a large number of design parameters by Wang, Shuai, Tian, Qiang, Hu, Haiyan, Shi, Junwei, Zeng, Lingbin

“…The reliability and dynamic performance of deployable flexible space structures significantly depend on their key design parameters. Sensitivity analysis of…”
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Environmental regulation, low-carbon technology progress and energy efficiency by Yu, Yingjing, Shi, Junwei

“…Low-carbon technological progress is an important way to achieve energy conservation and emission reduction, as well as achieve the goal of peaking carbon…”
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The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade by Cucolo, Lisa, Chen, Qingzhou, Qiu, Jingya, Yu, Yongjun, Klapholz, Max, Budinich, Krista A, Zhang, Zhaojun, Shao, Yue, Brodsky, Igor E, Jordan, Martha S, Gilliland, D Gary, Zhang, Nancy R, Shi, Junwei, Minn, Andy J

“…Interferon-gamma (IFN-γ) has pleiotropic effects on cancer immune checkpoint blockade (ICB), including roles in ICB resistance. We analyzed gene expression in…”
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