Search Results - "Shi, Jiahai"

Extrachromosomal circular DNA: a new potential role in cancer progression by Wang, Tianyi, Zhang, Haijian, Zhou, Youlang, Shi, Jiahai

“…Abstract Extrachromosomal circular DNA (eccDNA) is considered a circular DNA molecule that exists widely in nature and is independent of conventional…”
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Hypoxic ADSC-derived exosomes enhance wound healing in diabetic mice via delivery of circ-Snhg11 and induction of M2-like macrophage polarization by Shi, Rongfeng, Jin, Yinpeng, Zhao, Suming, Yuan, Hongxin, Shi, Jiahai, Zhao, Hui

“…Diabetes mellitus is a major cause of blindness and chronic ulcers in the working age population worldwide. Former research have found that differentially…”
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Efficient RNA drug delivery using red blood cell extracellular vesicles by Usman, Waqas Muhammad, Pham, Tin Chanh, Kwok, Yuk Yan, Vu, Luyen Tien, Ma, Victor, Peng, Boya, Chan, Yuen San, Wei, Likun, Chin, Siew Mei, Azad, Ajijur, He, Alex Bai-Liang, Leung, Anskar Y. H., Yang, Mengsu, Shyh-Chang, Ng, Cho, William C., Shi, Jiahai, Le, Minh T. N.

“…Most of the current methods for programmable RNA drug therapies are unsuitable for the clinic due to low uptake efficiency and high cytotoxicity. Extracellular…”
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Dynamically-driven enhancement of the catalytic machinery of the SARS 3C-like protease by the S284-T285-I286/A mutations on the extra domain by Lim, Liangzhong, Shi, Jiahai, Mu, Yuguang, Song, Jianxing

“…Previously we revealed that the extra domain of SARS 3CLpro mediated the catalysis via different mechanisms. While the R298A mutation completely abolished the…”
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Wdr26 regulates nuclear condensation in developing erythroblasts by Zhen, Ru, Moo, Chingyee, Zhao, Zhenzhen, Chen, Mengying, Feng, He, Zheng, Xiaojun, Zhang, Liang, Shi, Jiahai, Chen, Caiyong

“…Mammalian red blood cells lack nuclei. The molecular mechanisms underlying erythroblast nuclear condensation and enucleation, however, remain poorly…”
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Application of adipose-derived stem cells in ischemic heart disease: theory, potency, and advantage by Xiao, Weizhang, Shi, Jiahai

“…Adipose-derived mesenchymal stem cells (ASCs) represent an innovative candidate to treat ischemic heart disease (IHD) due to their abundance, renewable…”
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A cuproptosis score model and prognostic score model can evaluate clinical characteristics and immune microenvironment in NSCLC by Tang, Yijie, Wang, Tianyi, Li, Qixuan, Shi, Jiahai

“…Cuproptosis-related genes (CRGs) are associated with lung adenocarcinoma. However, the links between CRGs and non-small-cell lung cancer (NSCLC) are not clear…”
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A composite patch loaded with 2-Deoxy Glucose facilitates cardiac recovery after myocardial infarction via attenuating local inflammatory response by Xiao, Weizhang, Zhu, Zhen, Yu, Zhiming, Pan, Yue, Xue, Qun, Zhou, Youlang, Shi, Jiahai

“…Local inflammatory microenvironment in the early stage of myocardial infarction (MI) severely impaired cardiac recovery post-MI. Macrophages play a pivotal…”
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Engineered red blood cells as carriers for systemic delivery of a wide array of functional probes by Shi, Jiahai, Kundrat, Lenka, Pishesh, Novalia, Bilate, Angelina, Theile, Chris, Maruyama, Takeshi, Dougan, Stephanie K., Ploegh, Hidde L., Lodish, Harvey F.

“…We developed modified RBCs to serve as carriers for systemic delivery of a wide array of payloads. These RBCs contain modified proteins on their plasma…”
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Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation by Alvarez-Dominguez, Juan R., Hu, Wenqian, Yuan, Bingbing, Shi, Jiahai, Park, Staphany S., Gromatzky, Austin A., Oudenaarden, Alexander van, Lodish, Harvey F.

“…Erythropoiesis is regulated at multiple levels to ensure the proper generation of mature red cells under multiple physiological conditions. To probe the…”
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Nrf2 Promotes Inflammation in Early Myocardial Ischemia-Reperfusion via Recruitment and Activation of Macrophages by Zhang, Haijian, Liu, Yifei, Cao, Xiaoqing, Wang, Wenmiao, Cui, Xiaohong, Yang, Xuechao, Wang, Yan, Shi, Jiahai

“…Cardiomyocyte apoptosis in response to inflammation is a primary cause of myocardial ischemia-reperfusion injury (IRI). Nuclear factor erythroid 2 like 2…”
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Necroptosis Inhibition by Hydrogen Sulfide Alleviated Hypoxia-Induced Cardiac Fibroblasts Proliferation via Sirtuin 3 by Zhang, Yue, Gong, Weiwei, Xu, Mengting, Zhang, Shuping, Shen, Jieru, Zhu, Mingxian, Wang, Yuqin, Chen, Yun, Shi, Jiahai, Meng, Guoliang

“…Myocardial ischemia or hypoxia can induce myocardial fibroblast proliferation and myocardial fibrosis. Hydrogen sulfide (H S) is a gasotransmitter with…”
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Characteristic of molecular subtypes in lung adenocarcinoma based on m6A RNA methylation modification and immune microenvironment by Zhou, Hao, Zheng, Miaosen, Shi, Muqi, Wang, Jinjie, Huang, Zhanghao, Zhang, Haijian, Zhou, Youlang, Shi, Jiahai

“…Abstract Background Lung adenocarcinoma (LUAD) is a major subtype of lung cancer and closely associated with poor prognosis. N6-methyladenosine (m6A), one of…”
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Platelet membrane-camouflaged nanoparticles carry microRNA inhibitor against myocardial ischaemia‒reperfusion injury by Wang, Tianyi, Zhou, Tingting, Xu, Mingming, Wang, Shuo, Wu, Anqi, Zhang, Mingyang, Zhou, You Lang, Shi, Jiahai

“…Abstract The incidence of myocardial ischaemia‒reperfusion injury (MIRI) is increasing every year, and there is an urgent need to develop new therapeutic…”
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MicroRNA-125a-5p plays a role as a tumor suppressor in lung carcinoma cells by directly targeting STAT3 by Zhong, Lou, Sun, Siyuan, Shi, Jiahai, Cao, Fei, Han, Xiao, Chen, Zhong

“…Increasing evidence supports that the dysregulation of microRNA expression plays an important role in the process of tumor occurrence and development. Studies…”
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Mechanism for Controlling the Dimer-Monomer Switch and Coupling Dimerization to Catalysis of the Severe Acute Respiratory Syndrome Coronavirus 3C-Like Protease by Shi, Jiahai, Sivaraman, J, Song, Jianxing

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Transcriptional divergence and conservation of human and mouse erythropoiesis by Pishesha, Novalia, Thiru, Prathapan, Shi, Jiahai, Eng, Jennifer C., Sankaran, Vijay G., Lodish, Harvey F.

“…Mouse models have been used extensively for decades and have been instrumental in improving our understanding of mammalian erythropoiesis. Nonetheless, there…”
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Covalent conjugation of extracellular vesicles with peptides and nanobodies for targeted therapeutic delivery by Pham, Tin Chanh, Jayasinghe, Migara Kavishka, Pham, Thach Tuan, Yang, Yuqi, Wei, Likun, Usman, Waqas Muhammad, Chen, Huan, Pirisinu, Marco, Gong, Jinhua, Kim, Seongkyeol, Peng, Boya, Wang, Weixi, Chan, Charlene, Ma, Victor, Nguyen, Nhung T.H., Kappei, Dennis, Nguyen, Xuan‐Hung, Cho, William C., Shi, Jiahai, Le, Minh T.N.

“…Natural extracellular vesicles (EVs) are ideal drug carriers due to their remarkable biocompatibility. Their delivery specificity can be achieved by the…”
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miR‐335 inhibited cell proliferation of lung cancer cells by target Tra2β by Liu, Jian, Bian, Tingting, Feng, Jia, Qian, Li, Zhang, Jianguo, Jiang, Daishan, Zhang, Qing, Li, Xiaoli, Liu, Yifei, Shi, Jiahai

“…Accumulating evidence has suggested that the dysregulation of miRNA is an important factor in the pathogenesis of lung cancer. Here, we demonstrate that…”
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Roles of distinct nuclear receptors in diabetic cardiomyopathy by Zheng, Yangyang, Xu, Yongji, Ji, Li, San, Wenqing, Shen, Danning, Zhou, Qianyou, Meng, Guoliang, Shi, Jiahai, Chen, Yun

“…Diabetes mellitus induces a pathophysiological disorder known as diabetic cardiomyopathy and may eventually cause heart failure. Diabetic cardiomyopathy is…”
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