Search Results - "Shi, Dashuang"

Crystal structure of P. falciparum Cpn60 bound to ATP reveals an open dynamic conformation before substrate binding by Nguyen, Brian, Ma, Rui, Tang, Wai Kwan, Shi, Dashuang, Tolia, Niraj H.

“…Plasmodium falciparum harbors group 1 and group 2 chaperonin systems to mediate the folding of cellular proteins in different cellular locations. Two distinct…”
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Sources and Fates of Carbamyl Phosphate: A Labile Energy-Rich Molecule with Multiple Facets by Shi, Dashuang, Caldovic, Ljubica, Tuchman, Mendel

“…Carbamyl phosphate (CP) is well-known as an essential intermediate of pyrimidine and arginine/urea biosynthesis. Chemically, CP can be easily synthesized from…”
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From Genome to Structure and Back Again: A Family Portrait of the Transcarbamylases by Shi, Dashuang, Allewell, Norma M, Tuchman, Mendel

“…Enzymes in the transcarbamylase family catalyze the transfer of a carbamyl group from carbamyl phosphate (CP) to an amino group of a second substrate. The two…”
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The N-Acetylglutamate Synthase Family: Structures, Function and Mechanisms by Shi, Dashuang, Allewell, Norma M, Tuchman, Mendel

“…N-acetylglutamate synthase (NAGS) catalyzes the production of N-acetylglutamate (NAG) from acetyl-CoA and L-glutamate. In microorganisms and plants, the enzyme…”
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Crystal structure of the N-acetyltransferase domain of human N-acetyl-L-glutamate synthase in complex with N-acetyl-L-glutamate provides insights into its catalytic and regulatory mechanisms by Zhao, Gengxiang, Jin, Zhongmin, Allewell, Norma M, Tuchman, Mendel, Shi, Dashuang

“…N-acetylglutamate synthase (NAGS) catalyzes the conversion of AcCoA and L-glutamate to CoA and N-acetyl-L-glutamate (NAG), an obligate cofactor for carbamyl…”
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Mechanism of Allosteric Inhibition of N-Acetyl-L-glutamate Synthase by L-Arginine by Min, Li, Jin, Zhongmin, Caldovic, Ljubica, Morizono, Hiroki, Allewell, Norma M., Tuchman, Mendel, Shi, Dashuang

“…N-Acetylglutamate synthase (NAGS) catalyzes the first committed step in l-arginine biosynthesis in plants and micro-organisms and is subject to feedback…”
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A novel N-acetylglutamate synthase architecture revealed by the crystal structure of the bifunctional enzyme from Maricaulis maris by Shi, Dashuang, Li, Yongdong, Cabrera-Luque, Juan, Jin, Zhongmin, Yu, Xiaolin, Zhao, Gengxiang, Haskins, Nantaporn, Allewell, Norma M, Tuchman, Mendel

“…Novel bifunctional N-acetylglutamate synthase/kinases (NAGS/K) that catalyze the first two steps of arginine biosynthesis and are homologous to vertebrate…”
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The Crystal Structure of N-Acetyl-L-glutamate Synthase from Neisseria gonorrhoeae Provides Insights into Mechanisms of Catalysis and Regulation by Shi, Dashuang, Sagar, Vatsala, Jin, Zhongmin, Yu, Xiaolin, Caldovic, Ljubica, Morizono, Hiroki, Allewell, Norma M., Tuchman, Mendel

“…The crystal structures of N-acetylglutamate synthase (NAGS) in the arginine biosynthetic pathway of Neisseria gonorrhoeae complexed with acetyl-CoA and with…”
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Phenylalanines at positions 88 and 159 of Ebolavirus envelope glycoprotein differentially impact envelope function by Ou, Wu, King, Harlan, Delisle, Josie, Shi, Dashuang, Wilson, Carolyn A

“…Abstract The envelope glycoprotein (GP) of Ebolavirus (EBOV) mediates viral entry into host cells. Through mutagenesis, we and other groups reported that two…”
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Analysis of large phenotypic variability of EEC and SHFM4 syndromes caused by K193E mutation of the TP63 gene by Wei, Jianhua, Xue, Yang, Wu, Lian, Ma, Jie, Yi, Xiuli, Zhang, Junrui, Lu, Bin, Li, Chunying, Shi, Dashuang, Shi, Songtao, Feng, Xinghua, Cai, Tao

“…EEC (ectrodactyly, ectodermal dysplasia, clefting; OMIM 604292) is an autosomal dominant developmental disorder resulting mainly from pathogenic mutations of…”
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Acetylornithine Transcarbamylase: a Novel Enzyme in Arginine Biosynthesis by MORIZONO, Hiroki, CABRERA-LUQUE, Juan, DASHUANG SHI, GALLEGOS, Rene, YAMAGUCHI, Saori, XIAOLIN YU, ALLEWELL, Norma M, MALAMY, Michael H, TUCHMAN, Mendel

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cloning and expression of the human N-acetylglutamate synthase gene by Caldovic, Ljubica, Morizono, Hiroki, Gracia Panglao, Maria, Gallegos, Rene, Yu, Xiaolin, Shi, Dashuang, Malamy, Michael H, Allewell, Norma M, Tuchman, Mendel

“…N-acetylglutamate synthase (NAGS, E.C. 2.3.1.1) is a mitochondrial enzyme catalyzing the formation of N-acetylglutamate (NAG), an essential allosteric…”
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Structure and Catalytic Mechanism of a Novel N-Succinyl-l-ornithine Transcarbamylase in Arginine Biosynthesis of Bacteroides fragilis by Shi, Dashuang, Morizono, Hiroki, Cabrera-Luque, Juan, Yu, Xiaolin, Roth, Lauren, Malamy, Michael H., Allewell, Norma M., Tuchman, Mendel

“…A Bacteroides fragilis gene (argF′bf), the disruption of which renders the bacterium auxotrophic for arginine, was expressed and its recombinant protein…”
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Crystal structure of bullfrog M ferritin at 2.8 A resolution: analysis of subunit interactions and the binuclear metal center by Ha, Y, Shi, D, Small, G W, Theil, E C, Allewell, N M

“…Ferritins concentrate and store iron as a mineral in all bacterial, plant, and animal cells. The two ferritin subunit types, H or M (fast) and L (slow), differ…”
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Identification, cloning and expression of the mouse N-acetylglutamate synthase gene by Caldovic, Ljubica, Morizono, Hiroki, Yu, Xiaolin, Thompson, Mark, Shi, Dashuang, Gallegos, Rene, Allewell, Norma M, Malamy, Michael H, Tuchman, Mendel

“…In ureotelic animals, N-acetylglutamate (NAG) is an essential allosteric activator of carbamylphosphate synthetase I (CPSI), the first enzyme in the urea…”
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Crystal Structure of N-Acetylornithine Transcarbamylase from Xanthomonas campestris by Shi, Dashuang, Morizono, Hiroki, Yu, Xiaolin, Roth, Lauren, Caldovic, Ljubica, Allewell, Norma M., Malamy, Michael H., Tuchman, Mendel

“…We have identified in Xanthomonas campestris a novel N-acetylornithine transcarbamylase that replaces ornithine transcarbamylase in the canonic arginine…”
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Streptococcus pneumoniae Sialidase SpNanB-Catalyzed One-Pot Multienzyme (OPME) Synthesis of 2,7-Anhydro-Sialic Acids as Selective Sialidase Inhibitors by Xiao, An, Slack, Teri J, Li, Yanhong, Shi, Dashuang, Yu, Hai, Li, Wanqing, Liu, Yang, Chen, Xi

“…Streptococcus pneumoniae sialidase SpNanB is an intramolecular trans-sialidase (IT-sialidase) and a virulence factor that is essential for streptococcal…”
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9‑Azido-9-deoxy-2,3-difluorosialic Acid as a Subnanomolar Inhibitor against Bacterial Sialidases by Li, Wanqing, Santra, Abhishek, Yu, Hai, Slack, Teri J, Muthana, Musleh M, Shi, Dashuang, Liu, Yang, Chen, Xi

“…A library of 2­(a),3­(a/e)-difluorosialic acids and their C-5 and/or C-9 derivatives were chemoenzymatically synthesized. Pasteurella multocida sialic acid…”
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Structure and function of Escherichia coli RimK, an ATP-grasp fold, l-glutamyl ligase enzyme by Zhao, Gengxiang, Jin, Zhongmin, Wang, Yanli, Allewell, Norma M., Tuchman, Mendel, Shi, Dashuang

“…ABSTRACT We report herein the crystal structure of Escherichia coli RimK at a resolution of 2.85 Å, an enzyme that catalyzes the post‐translational addition of…”
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Quantification of benzoic, phenylacetic, and phenylbutyric acids from filter-paper blood spots by gas chromatography-mass spectrometry with stable isotope dilution by XIAOLIN YU, THOMPSON, Mark M, DASHUANG SHI, TUCHMAN, Mendel

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