Search Results - "Shewmaker, Frank P"

The Role of Post-Translational Modifications on Prion-Like Aggregation and Liquid-Phase Separation of FUS by Rhoads, Shannon N, Monahan, Zachary T, Yee, Debra S, Shewmaker, Frank P

“…Subcellular mislocalization and aggregation of the human FUS protein occurs in neurons of patients with subtypes of amyotrophic lateral sclerosis and…”
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The prionlike domain of FUS is multiphosphorylated following DNA damage without altering nuclear localization by Rhoads, Shannon N, Monahan, Zachary T, Yee, Debra S, Leung, Andrew Y, Newcombe, Cameron G, O'Meally, Robert N, Cole, Robert N, Shewmaker, Frank P

“…FUS (fused in sarcoma) is an abundant, predominantly nuclear protein involved in RNA processing. Under various conditions, FUS functionally associates with RNA…”
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Sex, prions, and plasmids in yeast by Kelly, Amy C, Shewmaker, Frank P, Kryndushkin, Dmitry, Wickner, Reed B

“…Even deadly prions may be widespread in nature if they spread by infection faster than they kill off their hosts. The yeast prions [PSI+] and [URE3] (amyloids…”
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Proteins with Intrinsically Disordered Domains Are Preferentially Recruited to Polyglutamine Aggregates by Wear, Maggie P, Kryndushkin, Dmitry, O'Meally, Robert, Sonnenberg, Jason L, Cole, Robert N, Shewmaker, Frank P

“…Intracellular protein aggregation is the hallmark of several neurodegenerative diseases. Aggregates formed by polyglutamine (polyQ)-expanded proteins, such as…”
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Yeast Models of Prion-Like Proteins That Cause Amyotrophic Lateral Sclerosis Reveal Pathogenic Mechanisms by Monahan, Zachary T, Rhoads, Shannon N, Yee, Debra S, Shewmaker, Frank P

“…Many proteins involved in the pathogenic mechanisms of amyotrophic lateral sclerosis (ALS) are remarkably similar to proteins that form prions in the yeast …”
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Yeast prions: structure, biology, and prion-handling systems by Wickner, Reed B, Shewmaker, Frank P, Bateman, David A, Edskes, Herman K, Gorkovskiy, Anton, Dayani, Yaron, Bezsonov, Evgeny E

“…A prion is an infectious protein horizontally transmitting a disease or trait without a required nucleic acid. Yeast and fungal prions are nonchromosomal genes…”
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Hepatic Expression of Serum Amyloid A1 Is Induced by Traumatic Brain Injury and Modulated by Telmisartan by Villapol, Sonia, Kryndushkin, Dmitry, Balarezo, Maria G, Campbell, Ashley M, Saavedra, Juan M, Shewmaker, Frank P, Symes, Aviva J

“…Traumatic brain injury affects the whole body in addition to the direct impact on the brain. The systemic response to trauma is associated with the hepatic…”
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Isolation and Analysis of Prion and Amyloid Aggregates from Yeast Cells by Kryndushkin, Dmitry, Pripuzova, Natalia, Shewmaker, Frank P

“…Amyloid fibers are large and extremely stable structures that can resist denaturation by strong anionic detergents, such as sodium dodecyl sulfate or sarkosyl…”
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Prions by Kryndushkin, Dmitry, Edskes, Herman K, Shewmaker, Frank P, Wickner, Reed B

“…Infectious proteins (prions) are usually self-templating filamentous protein polymers (amyloids). Yeast prions are genes composed of protein and, like the…”
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Genetic Methods for Studying Yeast Prions by Wickner, Reed B, Edskes, Herman K, Kryndushkin, Dmitry, Shewmaker, Frank P

“…The recognition that certain long-known nonchromosomal genetic elements were actually prions was based not on the specific phenotypic manifestations of those…”
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The relationship of prions and translation by Wickner, Reed B., Edskes, Herman K., Shewmaker, Frank P., Kryndushkin, Dmitry, Nemecek, Julie, McGlinchey, Ryan, Bateman, David

“…Prions are infectious proteins, without the need for an accompanying nucleic acid. Nonetheless, there are connections of prions with translation and RNA, which…”
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Sex, prions, and plasmids in yeast by Kelly, Amy C., Shewmaker, Frank P., Kryndushkin, Dmitry, Wickner, Reed B.

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Sex, prions, and plasmids in yeast by Kelly, Amy C, Shewmaker, Frank P, Kryndushkin, Dmitry, Wickner, Reed B

“…Even deadly prions may be widespread in nature if they spread by infection faster than they kill off their hosts. The yeast prions [PSI+] and [URE3] (amyloids…”
Get full text