Search Results - "Shevela, E Ya"

Effect of M2 Macrophage-Derived Soluble Factors on Behavioral Patterns and Cytokine Production in Various Brain Structures in Depression-Like Mice by Markova, E. V., Shevela, E. Ya, Knyazeva, M. A., Savkin, I. V., Serenko, E. V., Rashchupkin, I. M., Amstislavskaya, T. G., Ostanin, A. A., Chernykh, E. R.

“…We studied the effect of soluble factors derived from human macrophages polarized to M2 phenotype under conditions of serum deprivation (M2-SF) on behavioral…”
Get full text

Efferocytosis Modulates Arginase-1 and Tyrosine Kinase Mer Expression in GM-CSF-Differentiated Human Macrophages by Sakhno, L. V., Shevela, E. Ya, Tikhonova, M. A., Maksimova, A. A., Tyrinova, T. V., Ostanin, A. A., Chernykh, E. R.

“…We studied the expression of arginase-1 (Arg1) and tyrosine kinase Mer (MerTK) in GMCSF-differentiated human macrophage populations М0, М1(IFNγ), М2а(IL-4),…”
Get full text

Effect of M2 Macrophage-Derived Soluble Factors on Proliferation and Apoptosis of SH-SY5Y Cells by Rashchupkin, I. M., Maksimova, A. A., Sakhno, L. V., Ostanin, A. A., Shevela, E. Ya, Chernykh, E. R.

“…Macrophages play the key role in the regulation of neuroregeneration. For evaluation of the neuroregenerative potential of M2 macrophages, we studied the…”
Get full text

Influence of Secretome of Different Functional Phenotypes of Macrophages on Proliferation, Differentiation, and Collagen-Producing Activity of Dermal Fibroblasts In Vitro by Maksimova, A. A., Shevela, E. Ya, Sakhno, L. V., Tikhonova, M. A., Ostanin, A. A., Chernykh, E. R.

“…We studied the effect of conditioned media of GM-CSF-differentiated human macrophages polarized in M1(LPS), M2a(IL-4), M2c(dexamethasone), and M2(low serum)…”
Get full text

Efficiency of Cell Therapy in Liver Cirrhosis by Shevela, E. Ya, Starostina, N. M., Pal’tsev, A. I., Shipunov, M. V., Zheltova, O. I., Meledina, I. V., Khvan, L. A., Leplina, O. Yu, Ostanin, A. A., Chernykh, E. R., Kozlov, V. A.

“…We studied safety and clinical efficacy of transplantation of autologous bone marrow cell in complex therapy of 158 patients with chronic hepatitis and…”
Get full text

Intranasal immunotherapy with M2 macrophage soluble factors in post-COVID hyposmia: A pilot study by Shevela, E Ya, Davydova, M N, Meledina, I V, Bogachev, S S, Ostanin, A A, Kozlov, V A, Chernykh, E R

“…Olfactory dysfunction is an early marker of COVID-19 infection. However, individuals may develop chronic olfactory impairment for more than six months in…”
Get full text

Application of autologous bone marrow stem cells in the therapy of spinal cord injury patients by Chernykh, E R, Stupak, V V, Muradov, G M, Sizikov, M Yu, Shevela, E Ya, Leplina, O Yu, Tikhonova, M A, Kulagin, A D, Lisukov, I A, Ostanin, A A, Kozlov, V A

“…We studied the safety and efficiency of transplantation of autologous bone marrow cells in complex therapy of patients with spinal cord injury in the late…”
Get full text

Soluble human macrophage factors are able to inhibit TGF-β-induced differentiation of lung fibroblasts by Maksimova, A. A., Shevela, E. Ya, Sakhno, L. V.

“…Macrophages are key regulatory cells of fibrogenesis. They can have pro- or antifibrotic activity due to their plasticity and heterogeneity. Some studies have…”
Get full text

EFFECT OF M2 MACROPHAGE-DERIVED SOLUBLE FACTORS ON DIFFERENTIATION OF SH-SY5Y CELLS by Rashchupkin, I. M., Shevela, E. Ya, Chernykh, E. R.

“…Macrophages play a key role in triggering and regulation of neuroregeneration. The characteristic feature of macrophages is pronounced plasticity, which…”
Get full text

The Phenotypic and Functional Features of Human M2 Macrophages Generated Under Low Serum Conditions by Sakhno, L. V., Shevela, E. Ya, Tikhonova, M. A., Ostanin, A. A., Chernykh, E. R.

“…The phenotypic and functional features of human M2 macrophages, in particular, their immunosuppressive activity, can considerably vary depending on M2…”
Get full text

Angiogenin as a Possible Mediator of Macrophage-Mediated Regulation of Fibroblast Functions by Maksimova, A. A., Shevela, E. Ya, Tikhonova, M. A., Tyrinova, T. V., Bogachev, S. S., Ostanin, A. A., Chernykh, E. R.

“…We studied angiogenin production by human macrophages and evaluated the role of this factor in the macrophage-mediated regulation of fibroblasts. All…”
Get full text

Effect of soluble factors of macrophages polarized by efferocytosis on neuronal density in the frontal cortex and hippocampus of mice in a model of stress-induced depression by Rashchupkin, I. M., Amstislavskaya, T. G., Markova, E. V., Ostanin, A. A., Shevela, E. Ya

“…Recently, there has been a steady increase in depressive disorders, which occupy an important place in the structure of the causes of disability. In the…”
Get full text

Expression of arginase 1 and tyrosine kinase Mer by blood monocytes in the dynamics of physiological pregnancy by Shevela, E. Ya, Bukhtueva, N. G., Tikhonova, M. A., Sakhno, L. V., Pasman, N. M., Chernykh, E. R.

“…During pregnancy, the maternal immune system must maintain tolerance to paternal antigens, at the same time being able to eliminate pathogens, which is…”
Get full text

Expression of M2-associated molecules in circulating monocyte subsets in fertile non-pregnant women and pregnant women with uncomplicated pregnancy by Shevela, E. Ya, Bukhtueva, N. G., Tikhonova, M. A., Leplina, O. Yu, Pasman, N. M., Chernykh, E. R.

“…In humans circulating monocytes include classical (CD14 ++ CD16 - ), intermediate (CD14 ++ CD16 + ) and non-classical/alternative (CD14 + CD16 ++ ) monocytes,…”
Get full text

M-CSF and GM-CSF determinate fibromodulatory activity of polarized human macrophages by Maksimova, A. A., Shevela, E. Ya, Sakhno, L. V., Tikhonova, M. A., Ostanin, A. A., Chernykh, E. R.

“…GM-CSF and M-CSF, the hematopoietic colony-stimulating factors, induce various phenotypic changes in macrophage lineage populations and promote cell…”
Get full text

Comparative Efficacy of the Stromal-Vascular Fraction Cells of Lipoaspirate and Hyaluronic Acid in the Treatment of Gonarthrosis: Results of an Interim Analysis by Shevela, E. Ya, Glebova, T. R., Kotova, M. A., Nitsa, N. A., Kozhevnikov, Yu. A., Meledina, I. V., Ostanin, A. A., Chernykh, E. R.

“…The use of cell technologies, in particular the stromal-vascular fraction of adipose tissue, is a new direction in the treatment of osteoarthritis of the…”
Get full text

Common Ɣ-chain cytokine receptors as functional phenotype markers of PD-1and TIM-3-positive T cells in multiple myeloma by Batorov, E. V., Aristova, V. A., Ushakova, G. Yu, Sizikova, S. A., Denisova, V. V., Shevela, E. Ya, Ostanin, A. A., Chernykh, E. R.

“…T cells expressing checkpoint receptors PD-1, TIM-3 etc., are potential targets for monoclonal antibody immunotherapy in multiple myeloma (MM). However,…”
Get full text

Therapeutic effect of soluble factors of M2 phenotype macrophages in children with language impairments by Shevela, E. Ya, Degtyareva, V. G., Sosnovskaya, A. V., Voronova, E. V., Kafanova, M. Yu, Rashchupkin, I. M., Ostanin, A. A., Chernykh, E. R.

“…The aim of the present study was to assess safety and clinical efficacy of inhalation immunotherapy based on intranasal administration of bioactive factors…”
Get full text

Effect of Apoptotic Neutrophils on the Production of Erythropoietin, MMP-9, and TIMP-1 in Cultures of Human Macrophages by Sakhno, L. V., Shevela, E. Ya, Lykov, A. P., Poveshchenko, O. V., Ostanin, A. A., Chernykh, E. R.

“…We studied the effect of apoptotic neutrophils on the production of erythropoietin, MMP-9, and TIMP-1 by GM-CSF-induced human macrophages. GM-CSF-induced…”
Get full text

Characteristics of bone marrow cells under conditions of impaired innervation in patients with spinal trauma by Chernykh, E R, Shevela, E Ya, Leplina, O Yu, Tikhonova, M A, Ostanin, A A, Kulagin, A D, Pronkina, N V, Muradov, Zh M, Stupak, V V, Kozlov, V A

“…We studied quantitative and functional parameters of bone marrow stem cells and mature lymphocyte population under conditions of impaired innervation in…”
Get full text