Search Results - "Shevde, K"

1,25‐Dihydroxyvitamin D3 Stimulates Cyclic Vitamin D Receptor/Retinoid X Receptor DNA‐Binding, Co‐activator Recruitment, and Histone Acetylation in Intact Osteoblasts by Kim, Sungtae, Shevde, Nirupama K, Pike, J Wesley

“…1,25(OH)2D3 induces gene expression through the VDR. We used chromatin immunoprecipitation techniques to explore this 1,25(OH)2D3‐induced process on the…”
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Enhancers Located within Two Introns of the Vitamin D Receptor Gene Mediate Transcriptional Autoregulation by 1,25-Dihydroxyvitamin D3 by Zella, Lee A, Kim, Sungtae, Shevde, Nirupama K, Pike, J. Wesley

“…The biological actions of 1,25-(OH)2D3 are mediated by the vitamin D receptor (VDR), a protein that binds to target genes and alters their expression…”
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Estrogens Suppress RANK Ligand-Induced Osteoclast Differentiation via a Stromal Cell Independent Mechanism Involving c-Jun Repression by Shevde, Nirupama K., Bendixen, Amy C., Dienger, Krista M., Pike, J. Wesley

“…Loss of ovarian function following menopause results in a substantial increase in bone turnover and a critical imbalance between bone formation and resorption…”
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Distinct molecular mechanism for initiating TRAF6 signalling by Wu, Hao, Ye, Hong, Arron, Joseph R, Lamothe, Betty, Cirilli, Maurizio, Kobayashi, Takashi, Shevde, Nirupama K, Segal, Deena, Dzivenu, Oki K, Vologodskaia, Masha, Yim, Mijung, Du, Khoi, Singh, Sujay, Pike, J. Wesley, Darnay, Bryant G, Choi, Yongwon

“…Tumour-necrosis factor (TNF) receptor-associated factor 6 (TRAF6) is the only TRAF family member that participates in signal transduction of both the TNF…”
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Activation of Receptor Activator of NF-κB Ligand Gene Expression by 1,25-Dihydroxyvitamin D3 Is Mediated through Multiple Long-Range Enhancers by Kim, Sungtae, Yamazaki, Miwa, Zella, Lee A., Shevde, Nirupama K., Pike, J. Wesley

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Endogenous fluorescence signatures in living pluripotent stem cells change with loss of potency by Squirrell, Jayne M, Fong, Jimmy J, Ariza, Carlos A, Mael, Amber, Meyer, Kassondra, Shevde, Nirupama K, Roopra, Avtar, Lyons, Gary E, Kamp, Timothy J, Eliceiri, Kevin W, Ogle, Brenda M

“…The therapeutic potential of stem cells is limited by the non-uniformity of their phenotypic state. Thus it would be advantageous to noninvasively monitor stem…”
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2-Methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 Potently Stimulates Gene-specific DNA Binding of the Vitamin D Receptor in Osteoblasts by Yamamoto, Hironori, Shevde, Nirupama K., Warrier, Anjali, Plum, Lori A., DeLuca, Hector F., Pike, J.Wesley

“…2-Methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 (2MD) is a highly potent analog of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) whose actions are mediated through…”
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Multiple enhancer regions located at significant distances upstream of the transcriptional start site mediate RANKL gene expression in response to 1,25-dihydroxyvitamin D3 by Kim, Sungtae, Yamazaki, Miwa, Zella, Lee A., Meyer, Mark B., Fretz, Jackie A., Shevde, Nirupama K., Pike, J. Wesley

“…One of the primary regulators of receptor activator of NF-κB ligand (RANKL) is 1,25-dihydoxyvitamin D3 (1,25(OH)2D3). To elucidate the mechanism whereby…”
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Androgens Suppress Osteoclast Formation Induced by RANKL and Macrophage-Colony Stimulating Factor by Huber, Dustin M, Bendixen, Amy C, Pathrose, Peterson, Srivastava, Sunil, Dienger, Krista M, Shevde, Nirupama K, Pike, J. Wesley

“…Androgen deficiency in males leads to an increase in osteoclastic bone resorption and a progressive decrease in bone mineral density. In the current studies,…”
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A potent analog of 1α,25-dihydroxyvitamin D3 selectively induces bone formation by Shevde, Nirupama K., Plum, Lori A., Clagett-Dame, Margaret, Yamamoto, Hironori, Pike, J. Wesley, DeLuca, Hector F.

“…1,25-Dihydroxyvitamin D 3 [1,25(OH) 2 D 3 ] is a principal regulator of calcium and phosphorus homeostasis through actions on intestine, kidney, and bone…”
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The Human Transient Receptor Potential Vanilloid Type 6 Distal Promoter Contains Multiple Vitamin D Receptor Binding Sites that Mediate Activation by 1,25-Dihydroxyvitamin D3 in Intestinal Cells by Meyer, Mark B, Watanuki, Makoto, Kim, Sungtae, Shevde, Nirupama K, Pike, J. Wesley

“…Transient receptor potential vanilloid type 6 (TRPV6) (ECAC2, CaT1) is the major ion channel in intestinal epithelial cell membranes responsible for calcium…”
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A survey of 800 patients' knowledge, attitudes, and concerns regarding anesthesia by SHEVDE, K, PANAGOPOULOS, G

“…The present study was undertaken to assess patients' knowledge, attitudes, and concerns regarding anesthetic management. A survey of 34 items was developed and…”
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IL-4 Inhibits Osteoclast Formation through a Direct Action on Osteoclast Precursors via Peroxisome Proliferator-Activated Receptor γ1 by Bendixen, Amy C., Shevde, Nirupama K., Dienger, Krista M., Willson, Timothy M., Funk, Colin D., Pike, J. Wesley

“…IL-4 is a pleiotropic immune cytokine secreted by activated TH2 cells that inhibits bone resorption both in vitro and in vivo. The cellular targets of IL-4…”
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Vitamin D-Binding Protein Influences Total Circulating Levels of 1,25-Dihydroxyvitamin D3 but Does Not Directly Modulate the Bioactive Levels of the Hormone in Vivo by Zella, Lee A, Shevde, Nirupama K, Hollis, Bruce W, Cooke, Nancy E, Pike, J. Wesley

“…Mice deficient in the expression of vitamin D-binding protein (DBP) are normocalcemic despite undetectable levels of circulating 1,25-dihydroxyvitamin D3…”
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Transcriptional Control of Receptor Activator of Nuclear Factor-κB Ligand by the Protein Kinase A Activator Forskolin and the Transmembrane Glycoprotein 130-Activating Cytokine, Oncostatin M, Is Exerted through Multiple Distal Enhancers by Kim, Sungtae, Yamazaki, Miwa, Shevde, Nirupama K, Pike, J. Wesley

“…Receptor activator of nuclear factor-κB ligand (RankL) is a potent osteoclastogenic cytokine the expression of which is regulated at the transcriptional level…”
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1,25-Dihydroxyvitamin D3 Regulates the Expression of Low-Density Lipoprotein Receptor-Related Protein 5 via Deoxyribonucleic Acid Sequence Elements Located Downstream of the Start Site of Transcription by Fretz, Jackie A, Zella, Lee A, Kim, Sungtae, Shevde, Nirupama K, Pike, J. Wesley

“…The skeleton is a direct target of vitamin D action, where the hormone modulates the proliferation of osteoblast precursors, their differentiation into mature…”
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Comparative chondrogenesis of human cell sources in 3D scaffolds by Seda Tıǧlı, R., Ghosh, Sourabh, Laha, Michael M., Shevde, Nirupama K., Daheron, Laurence, Gimble, Jeffrey, Gümüşderelioǧlu, Menemşe, Kaplan, David L.

“…Cartilage tissue can be engineered by starting from a diversity of cell sources, including stem‐cell based and primary cell‐based platforms. Selecting an…”
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Estrogen modulates the recruitment of myelopoietic cell progenitors in rat through a stromal cell-independent mechanism involving apoptosis by SHEVDE, N. K, PIKE, J. W

“…Loss of ovarian function leads to a significant increase in the number of bone-resorbing osteoclasts. Estrogen replacement is known to manifest bone protective…”
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Enhanced activity of osteoblast differentiation factor (PEBP2αA2/CBFa1) in affected sutural osteoblasts from patients with Nonsyndromic craniosynostosis by SHEVDE, Nirupama K, BENDIXEN, Amy C, MARUYAMA, Midori, BAI LING LI, BILLMIRE, David A

“…Nonsyndromic craniosynostosis is characterized by premature closure of one or more cranial sutures in infants. The purpose of this investigation was to…”
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Perspectives on mechanisms of gene regulation by 1,25-dihydroxyvitamin D3 and its receptor by Pike, J. Wesley, Meyer, Mark B., Watanuki, Makoto, Kim, Sungtae, Zella, Lee A., Fretz, Jackie A., Yamazaki, Miwa, Shevde, Nirupama K.

“…1,25-Dihydroxyvitamin D3 (1,25(OH)2D3) functions as a systemic signal in vertebrate organisms to control the expression of genes whose products are vital to…”
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