Search Results - "Sheu, Wendy C"
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ZNF117 regulates glioblastoma stem cell differentiation towards oligodendroglial lineage
Published in Nature communications (22-04-2022)“…Glioblastoma (GBM) is a deadly disease without effective treatment. Because glioblastoma stem cells (GSCs) contribute to tumor resistance and recurrence,…”
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Brain-targeting, acid-responsive antioxidant nanoparticles for stroke treatment and drug delivery
Published in Bioactive materials (01-10-2022)“…Stroke is the leading cause of death and disability. Currently, there is no effective pharmacological treatment for this disease, which can be partially…”
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Targeted Delivery of Secretory Promelittin via Novel Poly(lactone‐co‐β‐amino ester) Nanoparticles for Treatment of Breast Cancer Brain Metastases
Published in Advanced science (01-03-2020)“…Breast cancer brain metastases (BCBM) is a devastating disease with dismal prognosis. Although chemotherapy is widely used for clinical management of most…”
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Autocatalytic, Brain Tumor‐Targeting Delivery of Bardoxolone Methyl Self‐Assembled Nanoparticles for Glioblastoma Treatment
Published in Small science (01-08-2024)“…Glioblastoma multiforme (GBM) is a formidable cancer to treat due to the lack of effective drugs that can also efficiently cross the blood–brain barrier (BBB)…”
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Biocompatibility of nanomaterials and their immunological properties
Published in Biomedical materials (Bristol) (01-07-2021)“…Nanomaterials (NMs) have revolutionized multiple aspects of medicine by enabling novel sensing, diagnostic, and therapeutic approaches. Advancements in…”
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Copresentation of Tumor Antigens and Costimulatory Molecules via Biomimetic Nanoparticles for Effective Cancer Immunotherapy
Published in Nano letters (10-06-2020)“…Nanoparticle (NP)-based cancer immunotherapy has been extensively explored. However, the efficacy of existing strategies is often limited by the lack of…”
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Cross-platform analysis reveals cellular and molecular landscape of glioblastoma invasion
Published in Neuro-oncology (Charlottesville, Va.) (14-03-2023)“…Abstract Background Improved treatment of glioblastoma (GBM) needs to address tumor invasion, a hallmark of the disease that remains poorly understood. In this…”
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Targeted disruption of tumor vasculature via polyphenol nanoparticles to improve brain cancer treatment
Published in Cell reports physical science (19-01-2022)“…Despite being effective for many other solid tumors, traditional anti-angiogenic therapy has been shown to be insufficient for the treatment of malignant…”
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Autocatalytic, Brain Tumor‐Targeting Delivery of Bardoxolone Methyl Self‐Assembled Nanoparticles for Glioblastoma Treatment
Published in Small science (01-08-2024)“…Glioblastoma Treatment In article number 2400081, Qianxue Chen, Xuan Xiao, Shenqi Zhang, and co‐workers developed and validated a novel nanotechnology‐based…”
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