Search Results - "Shetty, G A"

Curcumin treatment leads to better cognitive and mood function in a model of Gulf War Illness with enhanced neurogenesis, and alleviation of inflammation and mitochondrial dysfunction in the hippocampus by Kodali, M., Hattiangady, B., Shetty, G.A., Bates, A., Shuai, B., Shetty, A.K.

“…•Curcumin maintains better cognitive and mood function in a model of Gulf War Illness.•Curcumin alleviates neuroinflammation in a model of Gulf War…”
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In vivo gene transfer of nitric oxide synthase enhances vasomotor function in carotid arteries from normal and cholesterol-fed rabbits by CHANNON, K. M, HUSHENG QIAN, GEORGE, S. E, NEPLIOUEVA, V, BLAZING, M. A, OLMEZ, E, SHETTY, G. A, YOUNGBLOOD, S. A, PAWLOSKI, J, MCMAHON, T, STAMLER, J. S

“…The vascular endothelium is anatomically intact but functionally abnormal in preatherosclerotic states, and an early deficit in the bioavailability of nitric…”
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Adenoviral gene transfer of nitric oxide synthase : High level expression in human vascular cells by CHANNON, K. M, BLAZING, M. A, SHETTY, G. A, POTTS, K. E, GEORGE, S. E

“…Nitric oxide synthases (NOS) generate nitric oxide (NO), a second messenger with key regulatory roles. In the cardiovascular system, deficient endothelial NO…”
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Acute Host-Mediated Endothelial Injury After Adenoviral Gene Transfer in Normal Rabbit Arteries: Impact on Transgene Expression and Endothelial Function by Channon, Keith M, Qian, HuSheng, Youngblood, Scot A, Olmez, Ercument, Shetty, Geetha A, Neplioueva, Valentina, Blazing, Michael A, George, Samuel E

“…Acute injury after adenoviral vascular gene transfer remains incompletely characterized. Here, we describe the early response (<or=todays) in 52 New Zealand…”
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Hippocampal neurotrophin levels in a kainate model of temporal lobe epilepsy: a lack of correlation between brain‐derived neurotrophic factor content and progression of aberrant dentate mossy fiber sprouting by Shetty, Ashok K., Zaman, Vandana, Shetty, Geetha A.

“…A significant upregulation of neurotrophins particularly brain‐derived neurotrophic factor (BDNF) is believed to be involved in the initiation of epileptogenic…”
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Hippocampal neurotrophin levels after injury: Relationship to the age of the hippocampus at the time of injury by Shetty, Ashok K., Rao, Muddanna S., Hattiangady, Bharathi, Zaman, Vandana, Shetty, Geetha A.

“…Aging impairs the competence of the hippocampus for synaptic reorganization after injury. This potentially is due to the inability of the aging hippocampus to…”
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Efficient adenoviral gene transfer to early venous bypass grafts: comparison with native vessels by Channon, K M, Fulton, G J, Gray, J L, Annex, B H, Shetty, G A, Blazing, M A, Peters, K G, Hagen, P O, George, S E

“…Gene therapy may provide new approaches to reduce vein graft failure following coronary or peripheral bypass surgery. The aim of this study was to investigate…”
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Adenoviral gene transfer of nitric oxide synthase: High level expression in human vascular cells by Channon, Keith M., Blazing, Michael A., Shetty, Geetha A., Potts, Kevin E., George, Samuel E.

“…Objectives: Nitric oxide synthases (NOS) generate nitric oxide (NO), a second messenger with key regulatory roles. In the cardiovascular system, deficient…”
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Stem/progenitor cell proliferation factors FGF-2, IGF-1, and VEGF exhibit early decline during the course of aging in the hippocampus: Role of astrocytes by Shetty, Ashok K., Hattiangady, Bharathi, Shetty, Geetha A.

“…Dentate neurogenesis, important for learning and memory, declines dramatically by middle age. Although studies have shown that this age‐related decrease can be…”
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Brain-derived neurotrophic factor, phosphorylated cyclic AMP response element binding protein and neuropeptide Y decline as early as middle age in the dentate gyrus and CA1 and CA3 subfields of the hippocampus by Hattiangady, Bharathi, Rao, Muddanna S., Shetty, Geetha A., Shetty, Ashok K.

“…The hippocampus is very susceptible to aging. Severely diminished dentate neurogenesis at middle age is one of the most conspicuous early changes in the aging…”
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Nitric oxide synthase gene therapy rapidly reduces adhesion molecule expression and inflammatory cell infiltration in carotid arteries of cholesterol-fed rabbits by Qian, H, Neplioueva, V, Shetty, G A, Channon, K M, George, S E

“…Hypercholesterolemia reduces nitric oxide bioavailability, manifested by reduced endothelium-dependent vascular relaxation, and also induces vascular adhesion…”
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Efficient adenoviral gene transfer to early venous bypass grafts : comparison with native vessels: Gene therapy in the cardiovascular system by CHANNON, K. M, FULTON, G. J, GRAY, J. L, ANNEX, B. H, SHETTY, G. A, BLAZING, M. A, PETERS, K. G, HAGEN, P.-O, GEORGE, S. E

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