Search Results - "Sheth, Sameer A"
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Variability of white matter anatomy in the subcallosal cingulate area
Published in Human brain mapping (01-05-2021)“…The subcallosal cingulate (SCC) area is a putative hub in the brain network underlying depression. Deep brain stimulation (DBS) targeting a particular…”
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Normative vs. patient-specific brain connectivity in deep brain stimulation
Published in NeuroImage (Orlando, Fla.) (01-01-2021)“…Brain connectivity profiles seeding from deep brain stimulation (DBS) electrodes have emerged as informative tools to estimate outcome variability across DBS…”
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3
Functionally distinct high and low theta oscillations in the human hippocampus
Published in Nature communications (18-05-2020)“…Based on rodent models, researchers have theorized that the hippocampus supports episodic memory and navigation via the theta oscillation, a ~4–10 Hz rhythm…”
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Deep brain stimulation of the dorsal anterior cingulate cortex for the treatment of chronic neuropathic pain
Published in Neurosurgical focus (01-06-2015)“…Chronic neuropathic pain is estimated to affect 3%-4.5% of the worldwide population. It is associated with significant loss of productive time, withdrawal from…”
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Direct Electrical Stimulation of the Human Entorhinal Region and Hippocampus Impairs Memory
Published in Neuron (Cambridge, Mass.) (07-12-2016)“…Deep brain stimulation (DBS) has shown promise for treating a range of brain disorders and neurological conditions. One recent study showed that DBS in the…”
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Functionally Distinct Gamma Range Activity Revealed by Stimulus Tuning in Human Visual Cortex
Published in Current biology (21-10-2019)“…Neocortical gamma activity has long been hypothesized as a mechanism for synchronizing brain regions to support visual perception and cognition more broadly…”
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Clinical applications of magnetic resonance imaging based functional and structural connectivity
Published in NeuroImage (Orlando, Fla.) (01-12-2021)“…•Connectomics can help treatment planning in epilepsy and neuro-oncology.•Tractography can help motor thalamus targeting and has potential with other…”
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Direct Brain Stimulation Modulates Encoding States and Memory Performance in Humans
Published in Current biology (08-05-2017)“…People often forget information because they fail to effectively encode it. Here, we test the hypothesis that targeted electrical stimulation can modulate…”
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Lateralized hippocampal oscillations underlie distinct aspects of human spatial memory and navigation
Published in Nature communications (21-06-2018)“…The hippocampus plays a vital role in various aspects of cognition including both memory and spatial navigation. To understand electrophysiologically how the…”
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10
MRI-localized biopsies reveal subtype-specific differences in molecular and cellular composition at the margins of glioblastoma
Published in Proceedings of the National Academy of Sciences - PNAS (26-08-2014)“…Glioblastomas (GBMs) diffusely infiltrate the brain, making complete removal by surgical resection impossible. The mixture of neoplastic and nonneoplastic…”
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Aggressive resection at the infiltrative margins of glioblastoma facilitated by intraoperative fluorescein guidance
Published in Journal of neurosurgery (01-07-2017)“…OBJECTIVE Extent of resection is an important prognostic factor in patients undergoing surgery for glioblastoma (GBM). Recent evidence suggests that…”
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Computational modeling and minimization of unintended neuronal excitation in a LIFU stimulation
Published in Scientific reports (17-08-2023)“…The neuromodulation effect of low-intensity focused ultrasound (LIFU) is highly target-specific. Unintended off-target neuronal excitation can be elicited when…”
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Deep Brain Stimulation for Obsessive Compulsive Disorder: Evolution of Surgical Stimulation Target Parallels Changing Model of Dysfunctional Brain Circuits
Published in Frontiers in neuroscience (08-01-2019)“…Obsessive compulsive disorder (OCD) is a common, disabling psychiatric disease characterized by persistent, intrusive thoughts and ritualistic, repetitive…”
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Craniotomy and Survival for Primary Central Nervous System Lymphoma
Published in Neurosurgery (01-04-2019)“…Abstract BACKGROUND Cytoreductive surgery is considered controversial for primary central nervous system lymphoma (PCNSL). OBJECTIVE To investigate survival…”
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Stability of ripple events during task engagement in human hippocampus
Published in Cell reports (Cambridge) (29-06-2021)“…High-frequency activity bursts in the hippocampus, known as ripples, are thought to support memory consolidation during “offline” states, such as sleep…”
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The effects of direct brain stimulation in humans depend on frequency, amplitude, and white-matter proximity
Published in Brain stimulation (01-09-2020)“…Researchers have used direct electrical brain stimulation to treat a range of neurological and psychiatric disorders. However, for brain stimulation to be…”
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Neurosurgery for schizophrenia: an update on pathophysiology and a novel therapeutic target
Published in Journal of neurosurgery (01-04-2016)“…The main objectives of this review were to provide an update on the progress made in understanding specific circuit abnormalities leading to psychotic symptoms…”
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18
Functional neuroimaging of belief, disbelief, and uncertainty
Published in Annals of neurology (01-02-2008)“…Objective The difference between believing and disbelieving a proposition is one of the most potent regulators of human behavior and emotion. When one accepts…”
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Spontaneous neuronal oscillations in the human insula are hierarchically organized traveling waves
Published in eLife (26-05-2022)“…The insula plays a fundamental role in a wide range of adaptive human behaviors, but its electrophysiological dynamics are poorly understood. Here we used…”
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Similar patterns of neural activity predict memory function during encoding and retrieval
Published in NeuroImage (Orlando, Fla.) (15-07-2017)“…Neural networks that span the medial temporal lobe (MTL), prefrontal cortex, and posterior cortical regions are essential to episodic memory function in…”
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