Search Results - "Sheshagiri R. Dixit"

Enoyl ACP reductase as effective target for the synthesized novel antitubercular drugs: a-state-of-the-art by Joshi, Shrinivas D, Dixit, Sheshagiri R, More, Uttam A, Aminabhavi, Tejraj M, Kulkarni, Venkatrao H, Gadad, Andanappa K

“…The emergence of drug resistant strains of important human pathogens has created an urgent necessity to find new targets and novel antitubercular agents…”
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Synthesis, characterization and molecular docking studies of substituted 4-coumarinylpyrano[2,3-c]pyrazole derivatives as potent antibacterial and anti-inflammatory agents by Chougala, Bahubali M., Samundeeswari, S., Holiyachi, Megharaja, Shastri, Lokesh A., Dodamani, Suneel, Jalalpure, Sunil, Dixit, Sheshagiri R., Joshi, Shrinivas D., Sunagar, Vinay A.

“…A green, eco-friendly and efficient protocol has been developed and synthesized a series of coumarin based pyrano[2,3-c]pyrazole derivatives (3) by…”
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One pot Click chemistry: A three component reaction for the synthesis of 2-mercaptobenzimidazole linked coumarinyl triazoles as anti-tubercular agents by Anand, Ashish, Kulkarni, Manohar V., Joshi, Shrinivas D., Dixit, Sheshagiri R.

“…[Display omitted] •One pot synthesis and characterization of mercapto-coumarinyl triazoles.•Formation of 1,4 isomer under Cu(I) Click…”
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Synthesis and in vitro anticancer activity of 6-chloro-7-methyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one derivatives: molecular docking and interaction with bovine serum albumin by Gaonkar, Supreet, Sunagar, Manjunath G., Deshapande, Narahari, Belavagi, Ningaraddi S., Joshi, Shrinivas D, Dixit, Sheshagiri R, Khazi, Imtiyaz Ahmed M.

“…A novel series of 6-chloro-7-methyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one derivatives were synthesized. Structure of the newly synthesized compounds was…”
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Synthesis, molecular modeling and BACE-1 inhibitory study of tetrahydrobenzo[b] pyran derivatives by Bhaskar, Vijaya, Chowdary, Reshma, Dixit, Sheshagiri R., Joshi, Shrinivas D.

“…[Display omitted] •Small organic molecules were found to be effective inhibitors of BACE-1 enzyme.•Tetrahydrobenzo[b]pyrans were targeted for the BACE-1 enzyme…”
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Interaction of Hydralazine with Human Serum Albumin and Effect of β‑Cyclodextrin on Binding: Insights from Spectroscopic and Molecular Docking Techniques by Bolattin, Mallavva B, Nandibewoor, Sharanappa T, Joshi, Shrinivas D, Dixit, Sheshagiri R, Chimatadar, Shivamurti A

“…Biomolecular interaction of hydralazine with human serum albumin (HSA) was studied by fluorescence, ultravoilet, three-dimensional, synchronous, Fourier…”
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Virtual Screening of Alkaloids and Flavonoids as Acetylcholinesterase and MAO-B Inhibitors by Molecular Docking and Dynamic Simulation Studies by James, Jainey P., Sasidharan, Pradija, Mandal, Subhankar P., Dixit, Sheshagiri R.

“…The neuroprotective actions of flavonoids and alkaloids have been reported in many cognitive disorders. The study was focused on twenty-four phytoconstituents…”
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Discovery of Rhodanine and Thiazolidinediones as Novel Scaffolds for EGFR Inhibition: Design, Synthesis, Analysis and CoMSIA Studies by Francis, Tisa, Dixit, Sheshagiri R., Kumar, B. R. Prashantha

“…This study reports, 35 novel rhodanine, its bioisosteres thiazolidinediones and is tested for EGFR inhibition. These molecules are designed by using a…”
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Synthesis, antimycobacterial screening and ligand-based molecular docking studies on novel pyrrole derivatives bearing pyrazoline, isoxazole and phenyl thiourea moieties by Joshi, Shrinivas D., Dixit, Sheshagiri R., Kirankumar, M.N., Aminabhavi, Tejraj M., Raju, K.V.S.N., Narayan, Ramanuj, Lherbet, Christian, Yang, Kap Seung

“…We report here the synthesis, antibacterial and antitubercular evaluation of 61 novel pyrrolyl derivatives bearing pyrazoline, isoxazole and phenyl thiourea…”
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A click chemistry approach for the synthesis of mono and bis aryloxy linked coumarinyl triazoles as anti-tubercular agents by Anand, Ashish, Naik, Reshma J., Revankar, Hrishikesh M., Kulkarni, Manohar V., Dixit, Sheshagiri R., Joshi, Shrinivas D.

“…A series of mono and bis-triazole coumarin hybrids 6a–u and 9a–f respectively have been synthesized using 4-(azidomethyl)-2H-chromen-2-ones 5a–i and aryl…”
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Tetrazolylmethyl quinolines: Design, docking studies, synthesis, anticancer and antifungal analyses by Shaikh, Saba Kauser J., Kamble, Ravindra R., Somagond, Shilpa M., Devarajegowda, H.C., Dixit, Sheshagiri R., Joshi, Shrinivas D.

“…A new series of 2,5 and 1,5-regioisomers of the tetrazolyl group viz., 3-[(5-benzyl/benzylthio-2H-tetrazol-2-yl) methyl]-2-chloro-6-substituted quinoline 6h-q…”
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Synthesis, characterization and antitubercular activities of novel pyrrolyl hydrazones and their Cu-complexes by Joshi, Shrinivas D., Kumar, Devendra, Dixit, Sheshagiri R., Tigadi, Nageshwar, More, Uttam A., Lherbet, Christian, Aminabhavi, Tejraj M., Yang, Kap Seung

“…Novel pyrrolyl hydrazones and their copper complexes have been synthesized and characterized using analytical and spectral techniques to show the tetrahedral…”
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Green, unexpected synthesis of bis-coumarin derivatives as potent anti-bacterial and anti-inflammatory agents by Chougala, Bahubali M., Samundeeswari, S., Holiyachi, Megharaja, Naik, Nirmala S., Shastri, Lokesh A., Dodamani, Suneel, Jalalpure, Sunil, Dixit, Sheshagiri R., Joshi, Shrinivas D., Sunagar, Vinay A.

“…A green and efficient protocol has been developed and a series of coumarin based pyrano[3,2-c]chromene derivatives (2) have been synthesized using…”
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Benzothiazole derivatives as p53-MDM2 inhibitors: in-silico design, ADMET predictions, molecular docking, MM-GBSA Assay, MD simulations studies by N, Shridhar Deshpande, Shivakumar, Kumar D, Udaya, Ghate, Sudeep D, Dixit, Sheshagiri R, Awasthi, Abhimanyu, Revanasiddappa, B C

“…Breast cancer stands as the most prevalent malignancy among the female populace. One of the pivotal domains in the therapeutic landscape of breast cancer…”
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Isolation and characterization of ACE‐I inhibitory peptides from ribbonfish for a potential inhibitor of the main protease of SARS‐CoV‐2: An in silico analysis by G. Yathisha, Undiganalu, Srinivasa, Mahendra Gowdru, Siddappa BC, Revana, Mandal, Subankar, Dixit, Sheshagiri R., Pujar, G. V., Bangera Sheshappa, Mamatha

“…Recently, multifunctional fish peptides (FWPs) have gained a lot of attention because of their different biological activities. In the present study, three…”
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3,4-Dihydropyrimidinone-coumarin analogues as a new class of selective agent against S. aureus: Synthesis, biological evaluation and molecular modelling study by Naik, Nirmala S., Shastri, Lokesh A., Joshi, Shrinivas D., Dixit, Sheshagiri R., Chougala, Bahubali M., Samundeeswari, S., Holiyachi, Megharaj, Shaikh, Farzanabi, Madar, Jyoti, Kulkarni, Rashmi, Sunagar, Vinay

“…[Display omitted] •An efficient protocol has been developed for the synthesize of dihydropyrimidin-2(1H)-one/thione derivatives of coumarin from substituted…”
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Synthesis, biological evaluation and in silico molecular modeling of pyrrolyl benzohydrazide derivatives as enoyl ACP reductase inhibitors by Joshi, Shrinivas D., Dixit, Sheshagiri R., Kulkarni, Venkatarao H., Lherbet, Christian, Nadagouda, Mallikarjuna N., Aminabhavi, Tejraj M.

“…In efforts to develop lead anti-TB compounds, a novel series of 19 pyrrolyl benzohydrazides were synthesized and screened to target enoyl-ACP reductase enzyme,…”
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Pharmacophore mapping, molecular docking, chemical synthesis of some novel pyrrolyl benzamide derivatives and evaluation of their inhibitory activity against enoyl-ACP reductase (InhA) and Mycobacterium tuberculosis by Joshi, Shrinivas D., Dixit, Sheshagiri R., Basha, Jeelan, Kulkarni, V.H., Aminabhavi, Tejraj M., Nadagouda, Mallikarjuna N., Lherbet, Christian

“…[Display omitted] •A series of pyrrolyl benzamide derivatives have been designed and synthesized.•Compounds were characterized by IR, 1H NMR, 13C NMR and mass…”
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Molecular Docking and Three-Dimensional Quantitative Structure-Activity Relationships for Antitubercular Pyrimidine Derivatives by Parkali, Praveen M., Shyam Kumar, A., Johanna K, Pohamba, Prodensia T, Shilomboleni, Turaga, Sruthi, Shaiva, Vinod, Pujar, Gurubasavaraj V., Joshi, Shrinivas D., Aminabhavi, Tejraj M., Dixit, Sheshagiri R.

“…Enoyl Acyl Carrier Protein (ACP) Reductase, a key enzyme, which catalyzes the last reductive step of fatty acid biosynthesis and it, is one of the key enzymes…”
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Design and synthesis of coumarin–imidazole hybrid and phenyl-imidazoloacrylates as potent antimicrobial and antiinflammatory agents by Holiyachi, Megharaja, Samundeeswari, S., Chougala, Bahubali M., Naik, Nirmala S., Madar, Jyoti, Shastri, Lokesh A., Joshi, Shrinivas D., Dixit, Sheshagiri R., Dodamani, Suneel, Jalalpure, Sunil, Sunagar, Vinay A.

“…An improved one pot, multi-component synthesis of tri- and tetrasubstituted coumarin–imidazole hybrid has been synthesized at C4 position in good to excellent…”
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