Search Results - "Sherman, Paula A."

Elevated Blood Pressures in Mice Lacking Endothelial Nitric Oxide Synthase by Shesely, Edward G., Maeda, Nobuyo, H.-S. Kim, Desai, Kaushik M., Krege, John H., Laubach, Victor E., Sherman, Paula A., Sessa, William C., Smithies, Oliver

“…Nitric oxide produced in endothelial cells affects vascular tone. To investigate the role of endothelial nitrix oxide synthase (eNOS) in blood pressure…”
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Mice Lacking Inducible Nitric Oxide Synthase are Not Resistant to Lipopolysaccharide-Induced Death by Laubach, Victor E., Shesely, Edward G., Smithies, Oliver, Sherman, Paula A.

“…Nitric oxide produced by cytokine-inducible nitric oxide synthase (iNOS) is thought to be important in the pathogenesis of septic shock. To further our…”
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Purification and cDNA sequence of an inducible nitric oxide synthase from a human tumor cell line by Sherman, Paula A., Laubach, Victor E., Reep, Bryan R., Wood, Edgar R.

“…A combination of cytokines induced the expression of nitric oxide synthase (NOS) in a human colorectal adenocarcinoma cell line, DLD-1. We have purified the…”
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Transcriptional basis for hyporesponsiveness of the human inducible nitric oxide synthase gene to lipopolysaccharide/interferon-gamma by Zhang, Xiaoke, Laubach, Victor E., Alley, Evan W., Edwards, Kevin A., Sherman, Paula A., Russell, Stephen W., Murphy, William J.

“…The work reported here resolves, at the level of gene regulation, the controversy as to whether or not human monocytes/macrophages can produce nitric oxide…”
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High-Level Expression of Human Inducible Nitric Oxide Synthase in Chinese Hamster Ovary Cells and Characterization of the Purified Enzyme by Laubach, Victor E., Garvey, Edward P., Sherman, Paula A.

“…Chinese hamster ovary cells were transfected with the human inducible nitric oxide synthase (iNOS) cDNA under the control of the hCMV promoter. The NOS…”
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Purification and inhibitor screening of human nitric oxide synthase isozymes by Garvey, E P, Furfine, E S, Sherman, P A

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Analysis of expression and promoter function of the human inducible nitric oxide synthase gene in DLD-1 cells and monkey hepatocytes by Laubach, Victor E, Zhang, Charlotte X, Russell, Stephen W, Murphy, William J, Sherman, Paula A

“…Upon cytokine induction, inducible nitric oxide synthase (iNOS) mRNA and enzyme activity in DLD-1 cells reached maximal levels at 6 and 8 h, respectively. A…”
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Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas by Garvey, E P, Oplinger, J A, Tanoury, G J, Sherman, P A, Fowler, M, Marshall, S, Harmon, M F, Paith, J E, Furfine, E S

“…S-Ethylisothiourea was a potent competitive inhibitor of human nitric oxide synthase (NOS), with Ki values of 17, 36, and 29 nM for the inducible (i),…”
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Human Immunodeficiency Virus Integration Protein Expressed in Escherichia Coli Possesses Selective DNA Cleaving Activity by Sherman, Paula A., Fyfe, James A.

“…The human immunodeficiency virus (HIV) integration protein, a potential target for selective antiviral therapy, was expressed in Escherichia coli. The purified…”
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Enzymatic assay for deoxyribonucleoside triphosphates using synthetic oligonucleotides as template primers by Sherman, P A, Fyfe, J A

“…The enzymatic assay for deoxyribonucleoside triphosphates has been improved by using synthetic oligonucleotides of a carefully defined sequence as template…”
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Hepatocytes and macrophages express an identical cytokine inducible nitric oxide synthase gene by Wood, E R, Berger, Jr, H, Sherman, P A, Lapetina, E G

“…Polymerase chain reaction amplification of reverse transcribed RNA (RNA-PCR) was used to isolate overlapping cDNA clones encoding an inducible form of nitric…”
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Human immunodeficiency virus type 1 integration protein: DNA sequence requirements for cleaving and joining reactions by SHERMAN, P. A, DICKSON, M. L, FYFE, J. A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cobalamin Inhibition of HIV-1 Integrase and Integration of HIV-1 DNA into Cellular DNA by Weinberg, J.Brice, Shugars, Diane C., Sherman, Paula A., Sauls, Derrick L., Fyfe, James A.

“…Our prior studies showed that certain cobalamins inhibit productive HIV-1 infection of primary cultures of blood lymphocytes and monocytes. We demonstrate here…”
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Detailed Delineation of an Interferon-γ -Responsive Element Important in Human HLA-DRA Gene Expression in a Glioblastoma Multiform Line by Basta, Patricia V., Sherman, Paula A., Jenny P.-Y. Ting

“…In this report, we determined that induction of the DR α -chain gene by recombinant human interferon-γ (IFN-γ ) in a human glioblastoma multiform cell line is…”
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Upstream DNA Sequences Required for Tissue-Specific Expression of the HLA-DRα Gene by Sherman, Paula A., Basta, Patricia V., Jenny P.-Y. Ting

“…We have used in vitro deletion mutagenesis in combination with DNA transfection to search for cis-acting regulatory elements involved in the tissue-specific…”
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The Octamer Motif is a B-Lymphocyte-Specific Regulatory Element of the HLA-DRα gene Promoter by Sherman, Paula A., Basta, Patricia V., Heguy, Adriana, Wloch, Mary Kopke, Roeder, Robert G., Jenny P.-Y. Ting

“…The human class II gene, HLA-DRα , contains an octanucleotide sequence ATTTGCAT located ≈ 40 base pairs upstream of the transcription initiation site. We have…”
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Activation of ATPase of spinach coupling factor 1 by SHERMAN, Paula A., WIMMER, Mary J.

“…Several seemingly unrelated procedures used to elicit the latent ATPase activity of soluble spinach coupling factor 1 can be correlated to the release of…”
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Vitamin K epoxide reductase: evidence that vitamin K dihydroquinone is a product of vitamin K epoxide reduction by Sherman, P A, Sander, E G

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Class II Box Consensus Sequences in the HLA-DRα Gene: Transcriptional Function and Interaction with Nuclear Proteins by Sherman, Paula A., Basta, Patricia V., Moore, Terry L., Brown, Adrienne M., Ting, Jenny P.-Y.

“…The promoter regions of class II major histocompatibility complex genes contain two highly conserved sequences, the X and Y boxes, which may be involved in the…”
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Activation of ATPase of spinach coupling factor 1. Release of tightly bound ADP from the soluble enzyme by Sherman, P.A, Wimmer, M.J

“…Several seemingly unrelated procedures used to elicit the latent ATPase activity of soluble spinach coupling factor 1 can be correlated to the release of…”
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