Search Results - "Sheridan, Desmond J."

Achievements and Limitations of Evidence-Based Medicine by Sheridan, Desmond J., MD, PhD, Julian, Desmond G., MD

“…Abstract Evidence-based medicine (EBM) has a long history, but was revived in the early 1990s by a campaign mounted by a movement that took its name. The EBM…”
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Left ventricular hypertrophy induced by aortic banding impairs relaxation of isolated coronary arteries by McGoldrick, Rory B, Kingsbury, Martyn, Turner, Mark A, Sheridan, Desmond J, Hughes, Alun D

“…LVH (left ventricular hypertrophy) is associated with impaired coronary vascular reserve. In the present study, we examined the effect of pressure-overload…”
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Reversing the decline of academic medicine in Europe by Sheridan, Desmond J

“…Among the most cited scientists in medical research, less than half of those working in immunology, molecular biology, or pharmacology have a medical degree,…”
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Reply: The Efficacy of Exercise-Based Cardiac Rehabilitation: The Changing Face of Usual Care by Sheridan, Desmond J., Julian, Desmond G.

“…In our paper (1) we argued that the inclusion of clinical trials of rehabilitation carried out when survival of patients with coronary heart disease improved…”
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Mechanisms of coronary microcirculatory dysfunction in patients with aortic stenosis and angiographically normal coronary arteries by RAJAPPAN, Kim, RIMOLDI, Ornella E, DUTKA, David P, ARIFF, Ben, PENNELL, Dudley J, SHERIDAN, Desmond J, CAMICI, Paolo G

“…Development of left ventricular hypertrophy in aortic stenosis (AS) is accompanied by coronary microcirculatory dysfunction, demonstrated by an impaired…”
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Functional changes in coronary microcirculation after valve replacement in patients with aortic stenosis by RAJAPPAN, Kim, RIMOLDI, Ornella E, CAMICI, Paolo G, BELLENGER, Nicholas G, PENNELL, Dudley J, SHERIDAN, Desmond J

“…Increased extravascular compression and reduced diastolic perfusion time (DPT), rather than vascular remodeling, influence coronary microcirculatory…”
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Comparison of Coronary Vasodilator Reserve in Elite Rowing Athletes Versus Hypertrophic Cardiomyopathy by Radvan, Johannes, Choudhury, Lubna, Sheridan, Desmond J, Camici, Paolo G

“…Compared to normal volunteers, coronary vasodilation reserve is reduced in patients with hypertrophic cardiomyopathy but not in rowing athletes with left…”
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Regression of left ventricular hypertrophy in hypertensive patients treated with indapamide SR 1.5 mg versus enalapril 20 mg: the LIVE study by Gosse, Philippe, Sheridan, Desmond J, Zannad, Faiez, Dubourg, Olivier, Guéret, Pascal, Karpov, Yuri, de Leeuw, Peter W, Palma-Gamiz, Jose-Luis, Pessina, Achille, Motz, Wolfgang, Degaute, Jean-Paul, Chastang, Claude

“…OBJECTIVETo compare the efficacy of indapamide sustained release (SR) 1.5 mg and enalapril 20 mg at reducing left ventricular mass index (LVMI) in hypertensive…”
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"Bronchial artery delivery of viral vectors for gene delivery in cystic fibrosis; superior to airway delivery?" by Bakhai, Ameet, Sheridan, Desmond J, Coutelle, Charles C

“…Attempts at gene therapy for the pulmonary manifestations of Cystic Fibrosis have relied mainly on airway delivery. However the efficiency of gene transfer and…”
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Capillary filtration is reduced in lungs adapted to chronic heart failure : morphological and haemodynamic correlates by WENXIN HUANG, KINGSBURY, Martyn P, TURNER, Mark A, DONNELLY, J. Leo, FLORES, Nicholas A, SHERIDAN, Desmond J

“…To determine pulmonary capillary filtration in experimental chronic heart failure and to investigate some morphological and haemodynamic mechanisms that could…”
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The role of angiotensin receptor-1 blockade on electromechanical changes induced by left ventricular hypertrophy and its regression by GRAY, Rosaire P, TURNER, Mark A, SHERIDAN, Desmond J, FRY, Christopher H

“…The aims of this study were to: i) investigate the role of angiotensin in mediating changes to myocardial electromechanical properties during the development…”
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Complexities of equitable drug availability by Sheridan, Desmond J

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Electrophysiological effects accompanying regression of left ventricular hypertrophy by BOTCHWAY, Alfred N, TURNER, Mark A, SHERIDAN, Desmond J, FLORES, Nicholas A, FRY, Christopher H

“…The aim of this study was to investigate changes following regression of left ventricular hypertrophy (LVH). Electrophysiolological changes were recorded in…”
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Changes in QT interval with exercise in elite male rowers and controls by Rajappan, Kim, O’Connell, Clare, Sheridan, Desmond J

“…Background: QT interval prolongation occurs at rest and during exercise in pathological left ventricular hypertrophy. However, athletes with physiological…”
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Assessment of left ventricular mass regression after aortic valve replacement – cardiovascular magnetic resonance versus M-mode echocardiography by Rajappan, Kim, Bellenger, Nicholas G., Melina, Giovanni, Di Terlizzi, Marco, Yacoub, Magdi H., Sheridan, Desmond J., Pennell, Dudley J.

“…Objective: In patients with aortic valve disease, the presence of left ventricular hypertrophy (LVH) carries a significant risk of adverse cardiovascular…”
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Structural remodelling of lungs in chronic heart failure by Kingsbury, Martyn P, Huang, Wenxin, Donnelly, J Leo, Jackson, Emma, Needham, Emma, Turner, Mark A, Sheridan, Desmond J

“…In order to determine whether morphological changes could account for a previously reported reduction in pulmonary capillary filtration in heart failure, we…”
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Reply by Sheridan, Desmond J., Julian, Desmond G.

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Achievements and Limitations of Evidence-Based Medicine: State-of-the-Art Review: Point by Sheridan, Desmond J, Julian, Desmond G

“…Evidence-based medicine (EBM) has a long history, but was revived in the early 1990s by a campaign mounted by a movement that took its name. The EBM movement…”
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Contribution of nitric oxide and prostanoids to the cardiac electrophysiological and coronary vasomotor effects of diadenosine polyphosphates by Stavrou, B M, Sheridan, D J, Flores, N A

“…We investigated the hypothesis that the coronary vasomotor and cardiac electrophysiological effects of diadenosine polyphosphates (Ap(n)A) are mediated via…”
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Reduced Anisotropy of Action Potential Conduction in Left Ventricular Hypertrophy by CAREY, PETER A., TURNER, MARK, FRY, CHRISTOPHER H., SHERIDAN, DESMOND J.

“…Conduction and Left Ventricular Hypertrophy. Introduction: The aim of this study was to determine if anisotropic action potential conduction was altered during…”
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