Search Results - "Sheremet, Anna"
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Study of the Antibacterial Activity of Superhydrophilic and Superhydrophobic Copper Substrates against Multi-Drug-Resistant Hospital-Acquired Pseudomonas aeruginosa Isolates
Published in International journal of molecular sciences (08-01-2024)“…The global spread of multidrug-resistant (MDR) hospital-acquired pathogens is a serious problem for healthcare units. The challenge of the spreading of…”
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Fluorothiazinon, a small-molecular inhibitor of T3SS, suppresses salmonella oral infection in mice
Published in Journal of antibiotics (01-04-2021)“…Therapeutic strategies that target bacterial virulence have received considerable attention. The type III secretion system (T3SS) is important for bacterial…”
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Preventative treatment with Fluorothiazinon suppressed Acinetobacter baumannii-associated septicemia in mice
Published in Journal of antibiotics (01-03-2022)“…The high prevalence of multidrug-resistant Acinetobacter baumannii has emerged as a serious problem in the treatment of nosocomial infections in the past three…”
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Pharmacokinetics, quorum-sensing signal molecules and tryptophan-related metabolomics of the novel anti-virulence drug Fluorothiazinon in a Pseudomonas aeruginosa-induced pneumonia murine model
Published in Journal of pharmaceutical and biomedical analysis (30-11-2023)“…Pseudomonas aeruginosa (PA) infection is commonly associated with hospital-acquired infections in patients with immune deficiency and/or severe lung diseases…”
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Identification of Key TRIM Genes Involved in Response to Pseudomonas aeruginosa or Chlamydia spp. Infections in Human Cell Lines and in Mouse Organs
Published in International journal of molecular sciences (01-09-2023)“…Bacterial infections represent an unsolved problem today since bacteria can evade antibiotics and suppress the host’s immune response. A family of TRIM…”
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Pharmacokinetics, tissue distribution, bioavailability and excretion of the anti-virulence drug Fluorothiazinon in rats and rabbits
Published in Journal of antibiotics (01-06-2024)“…Growing antimicrobial resistance has accelerated the development of anti-virulence drugs to suppress bacterial toxicity without affecting cell viability…”
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New conjugates based on N4-hydroxycytidine with more potent antiviral efficacy in vitro than EIDD-2801 against SARS-CoV-2 and other human coronaviruses
Published in Antiviral research (01-05-2024)“…The spread of COVID-19 continues due to genetic variation in SARS-CoV-2. Highly mutated variants of SARS-CoV-2 have an increased transmissibility and immune…”
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Small Molecule Inhibitor of Type Three Secretion System Belonging to a Class 2,4-disubstituted-4H-[1,3,4]-thiadiazine-5-ones Improves Survival and Decreases Bacterial Loads in an Airway Pseudomonas aeruginosa Infection in Mice
Published in BioMed research international (01-01-2018)“…Pseudomonas aeruginosa is a cause of high mortality in burn, immunocompromised, and surgery patients. High incidence of antibiotic resistance in this pathogen…”
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Synthesis and Antiviral Activity of Novel β-D-N4-Hydroxycytidine Ester Prodrugs as Potential Compounds for the Treatment of SARS-CoV-2 and Other Human Coronaviruses
Published in Pharmaceuticals (Basel, Switzerland) (26-12-2023)“…The spread of COVID-19 infection continues due to the emergence of multiple transmissible and immune-evasive variants of the SARS-CoV-2 virus. Although various…”
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A New "Non-Traditional" Antibacterial Drug Fluorothiazinone-Clinical Research in Patients with Complicated Urinary Tract Infections
Published in Antibiotics (Basel) (22-05-2024)“…In order to combat resistance, it is necessary to develop antimicrobial agents that act differently from conventional antibiotics. Fluorothiazinone, 300 mg…”
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Study of the Antibacterial Activity of Superhydrophilic and Superhydrophobic Copper Substrates against Multi-Drug-Resistant Hospital-Acquired IPseudomonas aeruginosa/I Isolates
Published in International journal of molecular sciences (01-01-2024)“…The global spread of multidrug-resistant (MDR) hospital-acquired pathogens is a serious problem for healthcare units. The challenge of the spreading of…”
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Identification of Key ITRIM/I Genes Involved in Response to IPseudomonas aeruginosa/I or IChlamydia/I spp. Infections in Human Cell Lines and in Mouse Organs
Published in International journal of molecular sciences (01-08-2023)“…Bacterial infections represent an unsolved problem today since bacteria can evade antibiotics and suppress the host’s immune response. A family of TRIM…”
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PHSOR07 Presentation Time: 9:30 AM
Published in Brachytherapy (01-11-2024)Get full text
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PHSOR07 Presentation Time: 9:30 AM: In-House Developed Medical Device Software BiCycle for Automated BT Treatment Planning, Compliant with the European Medical Device Regulation (MDR)
Published in Brachytherapy (01-11-2024)“…Radiotherapy for locally advanced cervical cancer (LACC) according to Embrace-II consists of EBRT and image guided adaptive intracavitary/interstitial BT. BT…”
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