Search Results - "Sher, Dorie A"

Phase I Study of Oblimersen Sodium, an Antisense to Bcl-2, in Untreated Older Patients With Acute Myeloid Leukemia: Pharmacokinetics, Pharmacodynamics, and Clinical Activity by MARCUCCI, Guide, STOCK, Wendy, MORAN, Mollie, MAHARRY, Kati, NOVICK, Steven, BLOOMFIELD, Clara D, ZWIEBEL, James A, LARSON, Richard A, GREVER, Michael R, CHAN, Kenneth K, BYRD, John C, GUOWEI DAI, KLISOVIC, Rebecca B, SHUJUN LIU, KLISOVIC, Marko I, BLUM, William, KEFAUVER, Cheryl, SHER, Dorie A, GREEN, Margaret

“…Pharmacologic downregulation of Bcl-2, an antiapoptotic protein overexpressed in cancer, might increase chemosensitivity in acute myeloid leukemia (AML)…”
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Validation of a Next-Generation Sequencing Assay for Clinical Molecular Oncology by Cottrell, Catherine E, Al-Kateb, Hussam, Bredemeyer, Andrew J, Duncavage, Eric J, Spencer, David H, Abel, Haley J, Lockwood, Christina M, Hagemann, Ian S, O’Guin, Stephanie M, Burcea, Lauren C, Sawyer, Christopher S, Oschwald, Dayna M, Stratman, Jennifer L, Sher, Dorie A, Johnson, Mark R, Brown, Justin T, Cliften, Paul F, George, Bijoy, McIntosh, Leslie D, Shrivastava, Savita, Nguyen, TuDung T, Payton, Jacqueline E, Watson, Mark A, Crosby, Seth D, Head, Richard D, Mitra, Robi D, Nagarajan, Rakesh, Kulkarni, Shashikant, Seibert, Karen, Virgin, Herbert W, Milbrandt, Jeffrey, Pfeifer, John D

“…Currently, oncology testing includes molecular studies and cytogenetic analysis to detect genetic aberrations of clinical significance. Next-generation…”
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Treatment-influenced associations of PML-RARα mutations, FLT3 mutations, and additional chromosome abnormalities in relapsed acute promyelocytic leukemia by Gallagher, Robert E., Moser, Barry K., Racevskis, Janis, Poiré, Xavier, Bloomfield, Clara D., Carroll, Andrew J., Ketterling, Rhett P., Roulston, Diane, Schachter-Tokarz, Esther, Zhou, Da-cheng, Chen, I-Ming L., Harvey, Richard, Koval, Greg, Sher, Dorie A., Feusner, James H., Tallman, Martin S., Larson, Richard A., Powell, Bayard L., Appelbaum, Frederick R., Paietta, Elisabeth, Willman, Cheryl L., Stock, Wendy

“…Mutations in the all-trans retinoic acid (ATRA)–targeted ligand binding domain of PML-RARα (PRα/LBD+) have been implicated in the passive selection of…”
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Assaying Bcr-Abl kinase activity and inhibition in whole cell extracts by phosphorylation of substrates immobilized on agarose beads by Wu, Ding, Nair-Gill, Evan, Sher, Dorie A., Parker, Laurie L., Campbell, Jennifer M., Siddiqui, Mariah, Stock, Wendy, Kron, Stephen J.

“…There is a current and increasing demand for simple, robust, nonradioactive assays of protein tyrosine kinase activity with applications for clinical diagnosis…”
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Abl Kinase Domain Mutations Leading to Relapse of Ph+ Acute Lymphoblastic Leukemia (ALL) Occur Commonly and Can Be Detected At Initial Diagnosis: Molecular Results From CALGB 10001 by Koval, Gregory, Wetzler, Meir, Watson, Dorothy, Owzar, Kouros, Bloomfield, Clara D., Malnassy, Gregory, Sher, Dorie A., Larson, Richard A., Stock, Wendy

“…Abstract 2541 CALGB 10001 tested the feasibility of performing allogeneic or autologous stem cell transplantation (SCT) following combination chemotherapy and…”
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Clonal Markers In Relapsed Acute Promyelocytic Leukemia (APL): Clinicopathological Associations and Relation to All-Trans Retinoic Acid (ATRA) Treatment on Intergroup Phase III Trial C9710 by Gallagher, Robert E., Moser, Barry K., Racevskis, Janis, Poiré, Xavier, Bloomfield, Clara D., Carroll, Andrew J., Ketterling, Rhett, Ralston, Diane, Schachter-Tokarz, Esther, Zhou, Dacheng, Chen, I-Ming L., Harvey, Richard, Koval, Greg, Sher, Dorie A, Feusner, James H., Tallman, Martin S., Appelbaum, Frederick R., Larson, Richard A., Powell, Bayard L., Paietta, Elisabeth, Willman, Cheryl L., Stock, Wendy

“…Abstract 1038 The relationships of inherent disease-related characteristics and of treatment to the nature of APL cell clones that emerge at disease relapse…”
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Results of An International Study of Quantitative BCR/ABL Assays Using Defined RNA Samples by Sher, Dorie A., Miller, Jeffrey E., Wei, Qi, Radich, Jerald P., Wong, Chris L.P., Schrijver, Iris, McNeil, B. Kelly, Romeo, Elisa, Winstall, Eric, Zamora, Lurdes, Abbal, Claire, Pieters, Katrien, Colomer, Dolors, Maes, Brigitte, Lint, Phillippe Van, DeSchouwer, Pierre JJC, Bakkus, Marleen, Callens, Celine, Denys, Barbara, Boeckx, Nancy, Vandenberghe, Peter, Vaeyens, Freya, Fan, Hongxin, Taylor, Sherry, Georgiou, George, Monroe, Thomas J., Hocker, Kimberly, Webb-Martin, Teresa, Todd, Heather, Muniz-Fernandez, Adriana, Zhang, Hanfang, Starostik, Petr, Webb, C. Renee, Cai, Li, Watt, Christopher, Fletcher, Linda, Lambin, Suzan, Fuster, Oscar, Huang, Ying, Shaw, Jay H.

“…Abstract 2742 Molecular monitoring of BCR/ABL transcripts by real time quantitative reverse transcription PCR (qRT-PCR) is an essential technique for clinical…”
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Activation of the phosphatidylinositol 3-kinase serine kinase by IFN- alpha by Uddin, S, Fish, EN, Sher, DA, Gardziola, C, White, MF, Platanias, LC

“…During engagement of the type I IFN receptor, IRS-1 is phosphorylated on tyrosine and associates with the p85 regulatory subunit of the phosphatidylinositol…”
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Autologous Stem Cell Transplantation (SCT) Following Sequential Chemotherapy and Imatinib for Adults with Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL) — CALGB Study 10001 by Wetzler, Meir, Stock, Wendy, Donohue, Kathleen A., Owzar, Kouros, Sher, Dorie A., Hoke, Eva E., McCarty, John M., Blum, William G., Powell, Bayard L., Bloomfield, Clara D., Linker, Charles A., Larson, Richard A.

“…Imatinib, given sequentially or concomitantly with chemotherapy, now plays an important role in the frontline treatment of Ph+ ALL. Once in morphologic and…”
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Interaction of p59fynwith Interferon-Activated Jak Kinases by Uddin, Shahab, Sher, Dorie A., Alsayed, Yazan, Pons, Sebastian, Colamonici, Oscar R., Fish, Eleanor N., White, Morris F., Platanias, Leonidas C.

“…During IFNα stimulation, p59fynassociates with the Type I IFNR-associated Tyk-2 kinase in several human hematopoietic cell linesin vivo.This interaction is…”
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Low incidence of TAL1 gene rearrangements in adult acute lymphoblastic leukemia: A cancer and leukemia group B study (8762) by STOCK, W, WESTBROOK, C. A, FRANKEL, S. R, STEWART, C. C, BLOOMFIELD, C. D, SHER, D. A, DODGE, R, SOBOL, R. E, WURSTER-HILL, D, DAVEY, F. R, LARSON, R. A, LEBEAU, M. M, APLAN, P. D

“…TAL1 gene rearrangements have been described in approximately 25% of children with T cell acute lymphoblastic leukemia (ALL). Three percent of these…”
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