Search Results - "Shepro, D"

Pathophysiology of ischaemia reperfusion injury: central role of the neutrophil by Welbourn, C R, Goldman, G, Paterson, I S, Valeri, C R, Shepro, D, Hechtman, H B

“…Ischaemia is a common clinical event leading to local and remote injury. Evidence indicates that tissue damage is largely caused by activated neutrophils which…”
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Comparative Effects of Garlic and Aspirin on Diabetic Cardiovascular Complications by Patumraj, S, Tewit, S, Amatyakul, S, Jariyapongskul, A, Maneesri, S, Kasantikul, V, Shepro, D

“…By using streptozotocin-induced diabetic rats as a studied model, our previous experimental results have indicated that daily oral feeding of garlic extract…”
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Postischemic renal injury is mediated by neutrophils and leukotrienes by Klausner, J M, Paterson, I S, Goldman, G, Kobzik, L, Rodzen, C, Lawrence, R, Valeri, C R, Shepro, D, Hechtman, H B

“…Neutrophils have been implicated as central mediators in myocardial and skeletal muscle ischemia-reperfusion injury. This study tests whether these cellular…”
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Reactive oxygen species and elastase mediate lung permeability after acid aspiration by Goldman, G, Welbourn, R, Kobzik, L, Valeri, C R, Shepro, D, Hechtman, H B

“…Acid aspiration leads to increased neutrophil (PMN) oxidative metabolism, an event associated with lung leukosequestration and permeability increase…”
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Neutrophil elastase and oxygen radicals: synergism in lung injury after hindlimb ischemia by Welbourn, C R, Goldman, G, Paterson, I S, Valeri, C R, Shepro, D, Hechtman, H B

“…Hindlimb ischemia and reperfusion lead to lung injury dependent on activated polymorphonuclear neutrophils (PMN) adherence. This study tests whether elastase…”
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Image acquisition in 2-D electrophoresis by Patton, W F, Lim, M J, Shepro, D

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Protein detection using reversible metal chelate stains by Patton, W F, Lim, M J, Shepro, D

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The American Microcirculatory Society Landis Award lecture. Endothelial cells, inflammatory edema, and the microvascular barrier: comments by a "free radical" by Shepro, D

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Microvascular Pericyte Contractility in vitro: Comparison with Other Cells of the Vascular Wall by Kelley, Christine, D'Amore, Patricia, Hechtman, Herbert B., Shepro, David

“…Collagen lattices containing bovine retinal pericytes (RPs), vascular smooth muscle cells (VSMCs), pulmonary microvessel endothelial cells (PMECs), or aortic…”
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Role for tumor necrosis factor as mediator of lung injury following lower torso ischemia by Welbourn, R, Goldman, G, O'Riordain, M, Lindsay, T F, Paterson, I S, Kobzik, L, Valeri, C R, Shepro, D, Hechtman, H B

“…Ischemia and reperfusion of the ischemic lower torso lead to a neutrophil- (PMN) dependent lung injury characterized by PMN sequestration and permeability…”
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A CD18 antibody prevents lung injury but not hypotension after intestinal ischemia-reperfusion by Hill, J, Lindsay, T, Valeri, C R, Shepro, D, Hechtman, H B

“…Antibodies to the neutrophil CD18 integrin have been shown to ameliorate the local effects of intestinal ischemia and reperfusion (I/R). In addition to local…”
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P-selectin mediates intestinal ischemic injury by enhancing complement deposition by Gibbs, Simon A.L., Weiser, Martin R., Kobzik, Lester, Valeri, C. Robert, Shepro, David, Hechtman, Herbert B.

“…Background. Ischemia and reperfusion injury of rodent intestine is complement mediated. P-seletin antagonism reduces local injury, yet neutrophil depletion…”
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Selective propagation of retinal pericytes in mixed microvascular cell cultures using L-leucine-methyl ester by Lee, C S, Patton, W F, Chung-Welch, N, Chiang, E T, Spofford, K H, Shepro, D

“…Endothelial cell (EC) propagation has been simplified by developing cell-specific selection criteria. Methods commonly used for selectively isolating EC…”
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Noncardiogenic pulmonary edema after abdominal aortic aneurysm surgery by PATERSON, I. S, KLAUSNER, J. M, PUGATCH, R, ALLEN, P, MANNICK, J. A, SHEPRO, D, HECHTMAN, H. B

“…Limb ischemia in experimental animals leads to white blood cell (WBC) and thromboxane (Tx)A2 dependent pulmonary dysfunction. This study examines the pulmonary…”
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Lower torso ischemia-induced lung injury is leukocyte dependent by Klausner, J M, Anner, H, Paterson, I S, Kobzik, L, Valeri, C R, Shepro, D, Hechtman, H B

“…Lower torso ischemia leads on reperfusion to sequestration of polymorphonuclear leukocytes (PMN) in the lungs and increased permeability. This study tests the…”
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Hypoxia reoxygenation-induced injury of cultured pulmonary microvessel endothelial cells by Wiles, M E, Hechtman, H B, Morel, N M, Shepro, D

“…Polymorphonuclear leukocyte (PMN) sequestration within the pulmonary microvasculature is known to occur in association with ischemia/reoxygenation (I/R). This…”
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Phalloidin attenuates postischemic neutrophil infiltration and increased microvascular permeability by Korthuis, R J, Carden, D L, Kvietys, P R, Shepro, D, Fuseler, J

“…The aim of this study was to determine whether phalloidin (1 microM) or antamanide (1 microM), cyclic peptides that stabilize dense peripheral band and stress…”
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Endothelial-secreted arachidonic acid metabolites modulate polymorphonuclear leukocyte chemotaxis and diapedesis in vitro by Doukas, J, Hechtman, HB, Shepro, D

“…The influence of endothelial cells (ECs) on polymorphonuclear leukocyte (PMN) motility was examined using in vitro assays of PMN diapedesis and chemotaxis. ECs…”
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Thromboxane Mediates Diapedesis After Ischemia by Activation of Neutrophil Adhesion Receptors Interacting With Basally Expressed Intercellular Adhesion Molecule-1 by Goldman, Gideon, Welbourn, Richard, Klausner, Joseph M, Valeri, C R, Shepro, David, Hechtman, Herbert B

“…Ischemic injury is characterized by neutrophil (PMN)-endothelial cell adhesion and diapedesis associated with thromboxane (TX) generation…”
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Limb ischemia-induced increase in permeability is mediated by leukocytes and leukotrienes by KLAUSNER, J. M, PATERSON, I. S, VALERI, C. R, SHEPRO, D, HECHTMAN, H. B

“…This study tests the role of white blood cells (WBC) and leukotrienes in mediating the increased microvascular permeability following ischemia and reperfusion…”
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