Search Results - "Sheppard, Norman"
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First-in-human testing of a wirelessly controlled drug delivery microchip
Published in Science translational medicine (22-02-2012)“…The first clinical trial of an implantable microchip-based drug delivery device is discussed. Human parathyroid hormone fragment (1-34) [hPTH(1-34)] was…”
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Use of Subcutaneous Interstitial Fluid Glucose to Estimate Blood Glucose: Revisiting Delay and Sensor Offset
Published in Journal of diabetes science and technology (01-09-2010)“…Background: Estimates for delays in the interstitial fluid (ISF) glucose response to changes in blood glucose (BG) differ substantially among research groups…”
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Chronic, programmed polypeptide delivery from an implanted, multireservoir microchip device
Published in Nature biotechnology (01-04-2006)“…Implanted drug delivery systems are being increasingly used to realize the therapeutic potential of peptides and proteins. Here we describe the controlled…”
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A structure-based analysis of the vibrational spectra of nitrosyl ligands in transition-metal coordination complexes and clusters
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (2011)“…The vibrational spectra of nitrogen monoxide or nitric oxide (NO) bonded to one or to several transition-metal (M) atom(s) in coordination and cluster…”
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Electrothermally activated microchips for implantable drug delivery and biosensing
Published in Journal of controlled release (05-12-2005)“…Novel drug delivery and biosensing devices have the potential to increase the efficacy of drug therapy by providing physicians and patients the ability to…”
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Microfabricated Centrifugal Microfluidic Systems: Characterization and Multiple Enzymatic Assays
Published in Analytical chemistry (Washington) (15-10-1999)“…This paper describes a microfluidic system in which fluids are pumped by centrifugal force through microscopic channels defined in a plastic disk in order to…”
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Enzyme microgels in packed-bed bioreactors with downstream amperometric detection using microfabricated interdigitated microsensor electrode arrays
Published in Biotechnology and bioengineering (20-11-2001)“…In this article, we describe the use of pH‐ responsive hydrogels as matrices for the immobilization of two enzymes, glucose oxidase (GOx) and glutamate oxidase…”
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Edward Raymond Andrew. 27 June 1921 – 27 May 2001
Published in Biographical memoirs of fellows of the Royal Society (01-12-2003)“…1946) and by Felix Bloch of Stanford University (Bloch…”
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Functional Organization of Rat Olfactory Bulb Glomeruli Revealed by Optical Imaging
Published in The Journal of neuroscience (01-04-1998)“…The functional organization and synaptic physiology of olfactory bulb glomeruli were studied in rat in vitro slice preparations stained with the…”
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Model of an immobilized enzyme conductimetric urea biosensor
Published in Biosensors & bioelectronics (1996)“…A model for predicting the response of a conductimetric urea biosensor was developed and validated experimentally. The biosensor under consideration is formed…”
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Electrical conductivity measurements using microfabricated interdigitated electrodes
Published in Analytical chemistry (Washington) (01-05-1993)“…A study constructed interdigitated electrode arrays to be used as miniature conductivity cells. Values resulting from conducted arrays agreed well with…”
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Adhesion of polymer films to oxidized silicon and its effect on performance of a conductometric pH sensor
Published in Sensors and actuators. B, Chemical (1996)“…The use of a silane coupling agent, γ-methacryloxypropyl trimethoxysilane (γ-MPS), to promote adhesion of photolithographically patterned polymer hydrogels to…”
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Mapping Membrane Potential Transients in Crayfish (Procambarus clarkii) Optic Lobe Neuropils With Voltage-Sensitive Dyes
Published in Journal of neurophysiology (01-01-1999)“…Sergey Yagodin 1 , 3 , Carlos Collin 2 , Daniel L. Alkon 2 , Norman F. Sheppard Jr. 1 , and David B. Sattelle 3 1 Department of Biomedical Engineering, Johns…”
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The reliability of vibrational spectroscopy as a means of identification of the structures of chemisorbed species on metal surfaces: the cases of CO, NO and C 2 hydrocarbon surface species
Published in Catalysis today (15-10-2001)“…A review of the literature shows that vibrational spectroscopy has been extremely successful in anticipating the structures of C 2 chemisorbed species that are…”
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A method for studying swelling kinetics based on measurement of electrical conductivity
Published in Polymer gels and networks (01-04-1998)“…A novel method was applied to the study of swelling kinetics of pH-responsive hydrogels. This technique is based on the pH-dependent electrical conductivity of…”
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Edward Raymond Andrew
Published in Biographical memoirs of fellows of the Royal Society (2003)“…Raymond Andrew's career in nuclear magnetic resonance (NMR) began two years after the independent discoveries of the phenomenon by Edward Purcell of Harvard…”
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A guide to the complete interpretation of infrared spectra of organic structures
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (01-07-1995)Get full text
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Chronic, programmed polypeptide delivery from an implanted, multi reservoir microchip device
Published in Nature biotechnology (2006)Get full text
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The U.K.'s Contributions to IR Spectroscopic Instrumentation
Published in Analytical chemistry (Washington) (15-09-1992)“…The first commercially available infra-red (IR) spectrometer was designed in 1913 in London, and a number of UK academic spectroscopists worked in the IR…”
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