Search Results - "Sheppard, Michael C"

Prediction of all-cause and cardiovascular mortality in elderly people from one low serum thyrotropin result: a 10-year cohort study by Parle, James V, Maisonneuve, Patrick, Sheppard, Michael C, Boyle, Peter, Franklyn, Jayne A

“…Low serum thyrotropin, in combination with normal concentrations of circulating thyroid hormones, is common, especially in elderly people and in individuals…”
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Primary medical therapy for acromegaly by Sheppard, Michael C.

“…Summary There is now considerable evidence that the clinical outcome in patients with acromegaly can be improved very substantially by means of better surgical…”
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Prevalence of Subclinical Thyroid Dysfunction and Its Relation to Socioeconomic Deprivation in the Elderly: A Community-Based Cross-Sectional Survey by Wilson, Sue, Parle, James V., Roberts, Lesley M., Roalfe, Andrea K., Hobbs, F. D. Richard, Clark, Penny, Sheppard, Michael C., Gammage, Michael D., Pattison, Helen M., Franklyn, Jayne A.

“…Context: Population-based screening has been advocated for subclinical thyroid dysfunction in the elderly because the disorder is perceived to be common, and…”
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Sustaining fossil fuel use in a carbon-constrained world by rapid commercialization of carbon capture and sequestration by Sheppard, Michael C, Socolow, Robert H

“…Various aspects related to sustaining fossil fuel use in a carbon-constrained world by rapid commercialization of carbon capture and sequestration (CCS), are…”
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Mortality in Patients with Pituitary Disease by Sherlock, Mark, Ayuk, John, Tomlinson, Jeremy W, Toogood, Andrew A, Aragon-Alonso, Aurora, Sheppard, Michael C, Bates, Andrew S, Stewart, Paul M

“…Pituitary disease is associated with increased mortality predominantly due to vascular disease. Control of cortisol secretion and GH hypersecretion (and…”
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Long-Term Safety and Efficacy of Depot Long-Acting Somatostatin Analogs for the Treatment of Acromegaly by Ayuk, John, Stewart, Susan E., Stewart, Paul M., Sheppard, Michael C.

“…Depot somatostatin analogs are now increasingly being prescribed as adjuvant and primary therapy for the treatment of acromegaly. Previous studies have shown…”
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Cardiac Dysrhythmias and Thyroid Dysfunction - The Hidden Menace? by Osman, Faizel, Gammage, Michael D., Sheppard, Michael C., Franklyn, Jayne A.

“…Thyrotoxicosis is often perceived as a reversible disorder without long-term consequences, perhaps because of the availability of effective treatments, but…”
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Medical therapy in acromegaly by Sherlock, Mark, Woods, Conor, Sheppard, Michael C.

“…Acromegaly is a rare condition, which is associated with increased morbidity and mortality, both of which can be reduced with appropriate therapy. This Review…”
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Successful treatment of amiodarone-induced thyrotoxicosis by OSMAN, Faizel, FRANKLYN, Jayne A, SHEPPARD, Michael C, GAMMAGE, Michael D

“…Amiodarone-induced thyrotoxicosis (AIT) is a difficult management problem about which there are little published data. We examined whether continuing…”
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Heart rate variability and turbulence in hyperthyroidism before, during, and after treatment by Osman, Faizel, Franklyn, Jayne A., Daykin, Jacqueline, Chowdhary, Saqib, Holder, Roger L., Sheppard, Michael C., Gammage, Michael D.

“…Patients with subclinical and treated overt hyperthyroidism have an excess vascular mortality rate. Several symptoms and signs in overt hyperthyroidism suggest…”
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Thyroid Function and Mortality in Patients Treated for Hyperthyroidism by Franklyn, Jayne A, Sheppard, Michael C, Maisonneuve, Patrick

“…CONTEXT Hyperthyroidism has been reported to cause excess all-cause and circulatory mortality. Whether this can be reversed is unknown, as is the influence of…”
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Cardiovascular manifestations of hyperthyroidism before and after antithyroid therapy : A matched case-control study by OSMAN, Faizel, FRANKLYN, Jayne A, HOLDER, Roger L, SHEPPARD, Michael C, GAMMAGE, Michael D

“…This study sought to prospectively evaluate the prevalence of cardiovascular abnormalities in patients with overt hyperthyroidism before and after antithyroid…”
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Does acromegaly enhance mortality? by Ayuk, John, Sheppard, Michael C.

“…The increased mortality associated with acromegaly was first demonstrated in early epidemiological studies. Since the seminal paper by Wright et al. in 1970,…”
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A Paradigm Shift in the Monitoring of Patients With Acromegaly: Last Available Growth Hormone May Overestimate Risk by Sherlock, Mark, Reulen, Raoul C, Aragon-Alonso, Aurora, Ayuk, John, Clayton, Richard N, Sheppard, Michael C, Hawkins, Michael M, Bates, Andrew S, Stewart, Paul M

“…Context: Acromegaly is associated with reduced life expectancy, which has been reported to be normalized if treatment is successful in controlling GH/IGF-I…”
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Growth hormone assay standardization: an important clinical advance by Sheppard, Michael C.

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Fibroblast Growth Factors 1 and 2 and Fibroblast Growth Factor Receptor 1 Are Elevated in Thyroid Hyperplasia by Thompson, Stuart D, Franklyn, Jayne A, Watkinson, John C, Verhaeg, Julie M, Sheppard, Michael C, Eggo, Margaret C

“…We have previously reported increased expression of fibroblast growth factor (FGF-1 and FGF-2) in benign and malignant human thyroid neoplasia. To determine…”
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Treatment of Acromegaly with the Growth Hormone–Receptor Antagonist Pegvisomant by Trainer, Peter J, Drake, William M, Katznelson, Laurence, Freda, Pamela U, Herman-Bonert, Vivien, van der Lely, A.J, Dimaraki, Eleni V, Stewart, Paul M, Friend, Keith E, Vance, Mary Lee, Besser, G. Michael, Thorner, Michael O, Parkinson, Craig, Klibanski, Anne, Powell, Jeffrey S, Barkan, Ariel L, Sheppard, Michael C, Maldonado, Mario, Rose, D. Roderick, Clemmons, David R, Johannsson, Gudmundur, Bengt-Åke Bengtsson, Bengt-Åke, Stavrou, Stavros, Kleinberg, David L, Cook, David M, Phillips, Lawrence S, Bidlingmaier, Martin, Strasburger, Christian J, Hackett, Suzanne, Zib, Kenneth, Bennett, William F, Davis, Robert J, Scarlett, John A

“…Acromegaly is a chronic debilitating disorder resulting from excessive secretion of growth hormone and a resulting increase in the production of insulin-like…”
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Radioiodine treatment of hyperthyroidism-prognostic factors for outcome by ALLAHABADIA, Amit, DAYKIN, Jacquie, SHEPPARD, Michael C, GOUGH, Stephen C. L, FRANKLYN, Jayne A

“…There is little consensus regarding the most appropriate dose regimen for radioiodine (131I) in the treatment of hyperthyroidism. We audited 813 consecutive…”
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Growth hormone therapy does not induce cancer by Sheppard, Michael C

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Clinical review 142: cardiac dysrhythmias and thyroid dysfunction: the hidden menace? by Osman, Faizel, Gammage, Michael D, Sheppard, Michael C, Franklyn, Jayne A

“…Thyrotoxicosis is often perceived as a reversible disorder without long-term consequences, perhaps because of the availability of effective treatments, but…”
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