Search Results - "Sheppard, I J"

Anti‐PF4/heparin antibodies and venous graft occlusion in postcoronary artery bypass surgery patients randomized to postoperative unfractionated heparin or fondaparinux thromboprophylaxis by WARKENTIN, T. E., SHEPPARD, J. I., SUN, J. C. J., JUNG, H., EIKELBOOM, J. W.

“…Summary Background Anti‐PF4/heparin antibodies are frequently generated after coronary artery bypass grafting (CABG) surgery, with platelet‐activating IgG…”
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No significant improvement in diagnostic specificity of an anti‐PF4/polyanion immunoassay with use of high heparin confirmatory procedure by WARKENTIN, T. E., SHEPPARD, J. I.

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Quantitative interpretation of optical density measurements using PF4‐dependent enzyme‐immunoassays by WARKENTIN, T. E., SHEPPARD, J. I., MOORE, J. C., SIGOUIN, C. S., KELTON, J. G.

“…Background: Many laboratories test for heparin‐induced thrombocytopenia (HIT) using a PF4‐dependent enzyme‐immunoassay (EIA). An advantage of the EIA is its…”
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Fondaparinux treatment of acute heparin‐induced thrombocytopenia confirmed by the serotonin‐release assay: a 30‐month, 16‐patient case series by WARKENTIN, T. E., PAI, M., SHEPPARD, J. I., SCHULMAN, S., SPYROPOULOS, A. C., EIKELBOOM, J. W.

“…See also Greinacher A. Immunogenic but effective: the HIT‐fondaparinux brain puzzler. This issue, pp 2386–8; Goldfarb MJ, Blostein MD. Fondaparinux in acute…”
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Heparin‐induced thrombocytopenia: towards standardization of platelet factor 4/heparin antigen tests by GREINACHER, A., ITTERMANN, T., BAGEMÜHL, J., ALTHAUS, K., FÜRLL, B., SELLENG, S., LUBENOW, N., SCHELLONG, S., SHEPPARD, J. I., WARKENTIN, T.E.

“…Background: Laboratory confirmation of heparin‐induced thrombocytopenia (HIT) is based on detection of heparin‐dependent platelet‐activating antibodies…”
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Heparin‐induced thrombocytopenia – therapeutic concentrations of danaparoid, unlike fondaparinux and direct thrombin inhibitors, inhibit formation of platelet factor 4–heparin complexes by KRAUEL, K., FÜRLL, B., WARKENTIN, T. E., WEITSCHIES, W., KOHLMANN, T., SHEPPARD, J. I., GREINACHER, A.

“…Background: Treatment of heparin‐induced thrombocytopenia (HIT), a disorder in which anti‐platelet factor 4 (PF4)–heparin antibodies cause platelet activation…”
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Laryngeal squamous cell carcinoma presenting as a prelaryngeal, air-filled structure (pseudolaryngocoele) by Korampalli, T S, Belloso, A, Hans, P S, Irion, K, Sheppard, I J

“…We report a unique case of a squamous cell carcinoma of the larynx presenting as a large pseudolaryngocoele, arising through a thyroid cartilage defect. Case…”
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The use of well‐characterized sera for the assessment of new diagnostic enzyme‐immunoassays for the diagnosis of heparin‐induced thrombocytopenia by WARKENTIN, T. E., SHEPPARD, J. I., MOORE, J. C., KELTON, J. G.

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Performance characteristics of a rapid assay for anti‐PF4/heparin antibodies: the particle immunofiltration assay by WARKENTIN, T. E., SHEPPARD, J. I., RASCHKE, R., GREINACHER, A.

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Generation of platelet-derived microparticles and procoagulant activity by heparin-induced thrombocytopenia IgG/serum and other IgG platelet agonists: a comparison with standard platelet agonists by Sheppard, T.E. Warkentin, J.I.

“…Heparin-induced thrombocytopenia (HIT) is a relatively common, immunoglobulin-mediated adverse drug reaction associated with in vivo thrombin generation and…”
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Clinical sample investigation (CSI) hematology: pinpointing the precise onset of heparin‐induced thrombocytopenia (HIT) by WARKENTIN, T. E., SHEPPARD, J. I.

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MRI in the detection of acoustic neuromas--a suggested protocol for screening by Sheppard, I J, Milford, C A, Anslow, P

“…Magnetic resonance imaging (MRI) is the definitive investigation in the detection of an acoustic neuroma and its use is becoming increasingly widespread for…”
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States in adherent platelet morphology and the processing of adsorbed protein on biomaterials by Feuerstein, I A, Sheppard, J I

“…This study evaluates the range of adherent platelet morphologies and their relationship to preadsorbed protein. Fluorescently labelled protein was used so…”
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Conservation surgery in head and neck cancer by Sheppard, I. J., Watkinson, J. C., Glaholm, J.

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Organization of day-case adenoidectomy in the management of chronic otitis media with effusion-preliminary results by SHEPPARD, I. J, MOIR, A. A, THOMAS, R. S. A, NARULA, A. A

“…We report our initial findings of adenoidectomy performed in Leicester as a day case on 149 children between the ages of 3 and 9 years, who have been assessed…”
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Adherent platelet morphology on adsorbed fibrinogen: effects of protein incubation time and albumin addition by Sheppard, J I, McClung, W G, Feuerstein, I A

“…The composition of the protein layer adsorbed to a polymer has been thought to be important for the adhesion of platelets. The state of activation of adherent…”
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In vitro leukocyte adhesion to modified polyurethane surfaces: III. Effect of flow, fluid medium, and platelets on PMN adhesion by Bruil, A, Sheppard, J I, Feijen, J, Feuerstein, I A

“…The operation of filters used to remove leukocytes from red cell concentrates may depend on the adhesion and mechanical trapping of leukocytes. If adhesion is…”
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HIT complicating fondaparinux prophylaxis: fondaparinux-dependent platelet activation as a marker for fondaparinux-induced HIT by Warkentin, T E, Sheppard, J-A I, Manheim, J C

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The serological profile of fondaparinux-associated heparin-induced thrombocytopenia syndrome by Warkentin, Theodore E, Chakraborty, Anup K, Sheppard, Jo-Ann I, Griffin, Danielle K

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Is emergency laryngectomy a waste of time? by Narula, A A, Sheppard, I J, West, K, Bradley, P J

“…Patients who present with airway obstruction due to carcinoma of the larynx may be managed by tracheotomy followed by definitive tumor surgery at a later date…”
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