Search Results - "Shepherd, Pat"

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    Second-generation tyrosine kinase inhibitors improve the survival of patients with chronic myeloid leukemia in whom imatinib therapy has failed by IBRAHIM, Amr R, CLARK, Richard E, HOLYOAKE, Tessa L, BYRNE, Jenny, SHEPHERD, Pat, APPERLEY, Jane F, MILOJKOVIC, Dragana, SZYDLO, Richard, GOLDMAN, John, MARIN, David

    Published in Haematologica (Roma) (01-12-2011)
    “…It has not been clearly established whether second-generation tyrosine kinase inhibitors actually improve the survival of patients with chronic myeloid…”
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    Journal Article
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    Treatment of CML using IFN-alpha: impact on quality of life by Homewood, Janis, Watson, Maggie, Richards, Sue M, Halsey, Jim, Shepherd, Pat C A

    “…Treatment of chronic myeloid leukaemia (CML) with IFN-alpha (IFN) is known to confer significant survival benefit, but the drug's impact on quality of life…”
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    Panhypopituitarism secondary to a macroprolactinoma manifesting with pancytopenia: case report and literature review by Holmes, George I, Shepherd, Pat, Walker, James D

    Published in Endocrine practice (01-03-2011)
    “…To present a case of pancytopenia associated with hypopituitarism secondary to a macroprolactinoma. We report the clinical features on presentation and results…”
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    Complete molecular responses are achieved after reduced intensity stem cell transplantation and donor lymphocyte infusion in chronic myeloid leukemia by Heaney, Nicholas B., Copland, Mhairi, Stewart, Karen, Godden, Judith, Parker, Anne N., McQuaker, I. Grant, Smith, Graeme M., Crawley, Charles, Shepherd, Pat, Holyoake, Tessa L.

    Published in Blood (15-05-2008)
    “…Patients with newly diagnosed chronic phase chronic myeloid leukemia were treated with imatinib mesylate (IM) for 6 to 12 months to establish disease control,…”
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    Reduced Intensity Stem Cell Transplantation and Donor Lymphocyte Infusion after Imatinib Induction To Eradicate Residual Disease in Chronic Myeloid Leukaemia by Heaney, Nicholas, Copland, Mhairi, Stewart, Karen, Godden, Judith, Parker, Anne, McQuaker, Grant, Smith, Graeme, Crawley, Charles, Shepherd, Pat, Holyoake, Tessa L.

    Published in Blood (16-11-2007)
    “…Recommended first-line therapy for patients with chronic phase (CP) CML is imatinib mesylate (IM). Although IM induces complete cytogenetic responses (CCR) in…”
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    Survival of patients with chronic-phase chronic myeloid leukaemia on imatinib after failure on interferon alfa by Marin, David, Marktel, Sarah, Szydlo, Richard, Klein, John P, Bua, Marco, Foot, Nicola, Olavarria, Eduardo, Shepherd, Pat, Kanfer, Edward, Goldman, John M, Apperley, Jane F

    Published in The Lancet (British edition) (23-08-2003)
    “…Until the recent introduction of imatinib, interferon alfa was the standard treatment for patients in the chronic phase of chronic myeloid leukaemia. We…”
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    The impact of the combination of baseline risk group and cytogenetic response on the survival of patients with chronic myeloid leukemia treated with interferon alpha by Hasford, J, Pfirrmann, M, Shepherd, P, Guilhot, J, Hehlmann, R, Mahon, FX, Kluin-Nelemans, HC, Ohnishi, K, Steegmann, JL, Thaler, J

    Published in Haematologica (Roma) (01-03-2005)
    “…Universite Victor Segalen, Bordeaux, France; University Hospital Groningen, Groningen, The Netherlands. has@ibe.med.uni-muenchen.de BACKGROUND AND OBJECTIVES:…”
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    Successful use of National Cancer Registry data to monitor the effective use of imatinib for treating chronic myeloid leukaemia by Shepherd, P, Dhanapala, C, Maguire, C, White, J, Drummond, M, Holyoake, T, Johnson, P R E

    Published in Scottish medical journal (01-08-2008)
    “…Imatinib is a tyrosine kinase inhibitor, which selectively antagonises the BCR-ABL molecular pathway which causes chronic myeloid leukaemia (CML). Imatinib was…”
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