Search Results - "Shepherd, Pat"
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Early prediction of success or failure of treatment with second-generation tyrosine kinase inhibitors in patients with chronic myeloid leukemia
Published in Haematologica (Roma) (01-02-2010)“…Second-generation tyrosine kinase inhibitors induce cytogenetic responses in approximately 50% of patients with chronic myeloid leukemia in chronic phase in…”
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Second-generation tyrosine kinase inhibitors improve the survival of patients with chronic myeloid leukemia in whom imatinib therapy has failed
Published in Haematologica (Roma) (01-12-2011)“…It has not been clearly established whether second-generation tyrosine kinase inhibitors actually improve the survival of patients with chronic myeloid…”
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Treatment of CML using IFN-alpha: impact on quality of life
Published in The hematology journal : the official journal of the European Haematology Association (2003)“…Treatment of chronic myeloid leukaemia (CML) with IFN-alpha (IFN) is known to confer significant survival benefit, but the drug's impact on quality of life…”
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Restricted access to second generation tyrosine kinase inhibitors in the UK could result in suboptimal treatment for almost half of chronic myeloid leukaemia patients: results from a West of Scotland and Lothian population study
Published in British journal of haematology (01-10-2011)Get full text
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Panhypopituitarism secondary to a macroprolactinoma manifesting with pancytopenia: case report and literature review
Published in Endocrine practice (01-03-2011)“…To present a case of pancytopenia associated with hypopituitarism secondary to a macroprolactinoma. We report the clinical features on presentation and results…”
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Complete molecular responses are achieved after reduced intensity stem cell transplantation and donor lymphocyte infusion in chronic myeloid leukemia
Published in Blood (15-05-2008)“…Patients with newly diagnosed chronic phase chronic myeloid leukemia were treated with imatinib mesylate (IM) for 6 to 12 months to establish disease control,…”
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Reduced Intensity Stem Cell Transplantation and Donor Lymphocyte Infusion after Imatinib Induction To Eradicate Residual Disease in Chronic Myeloid Leukaemia
Published in Blood (16-11-2007)“…Recommended first-line therapy for patients with chronic phase (CP) CML is imatinib mesylate (IM). Although IM induces complete cytogenetic responses (CCR) in…”
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A Phase 3 Pilot Study of Continuous Imatinib Versus Pulsed Imatinib with or without G-CSF in Patients with Chronic Phase CML Who Have Achieved a Complete Cytogenetic Response to Imatinib
Published in Blood (16-11-2007)“…Imatinib mesylate (IM) induces complete cytogenetic responses (CCR) in the majority of patients with CML in chronic phase (CP). Despite this reduction in…”
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Survival of patients with chronic-phase chronic myeloid leukaemia on imatinib after failure on interferon alfa
Published in The Lancet (British edition) (23-08-2003)“…Until the recent introduction of imatinib, interferon alfa was the standard treatment for patients in the chronic phase of chronic myeloid leukaemia. We…”
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The impact of the combination of baseline risk group and cytogenetic response on the survival of patients with chronic myeloid leukemia treated with interferon alpha
Published in Haematologica (Roma) (01-03-2005)“…Universite Victor Segalen, Bordeaux, France; University Hospital Groningen, Groningen, The Netherlands. has@ibe.med.uni-muenchen.de BACKGROUND AND OBJECTIVES:…”
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Successful use of National Cancer Registry data to monitor the effective use of imatinib for treating chronic myeloid leukaemia
Published in Scottish medical journal (01-08-2008)“…Imatinib is a tyrosine kinase inhibitor, which selectively antagonises the BCR-ABL molecular pathway which causes chronic myeloid leukaemia (CML). Imatinib was…”
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Not so NICE for CML
Published in The Lancet (British edition) (08-06-2002)Get full text
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Readers to the Rescue: Online Shopping
Published in Times (London, England : 1788) (29-03-2008)Get full text
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Readers to the Rescue: Online Investment
Published in Times (London, England : 1788) (15-03-2008)Get full text
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