Search Results - "Shephard, E G"

Miocene drainage reversal of the Amazon River driven by plate-mantle interaction by Shephard, G. E, Liu, L, Müller, R. D, Gurnis, M

“…Northern South America experienced significant changes in drainage patterns during the opening of the South Atlantic Ocean. Disappearance of a mega-wetland in…”
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On the consistency of seismically imaged lower mantle slabs by Shephard, G. E., Matthews, K. J., Hosseini, K., Domeier, M.

“…The geoscience community is increasingly utilizing seismic tomography to interpret mantle heterogeneity and its links to past tectonic and geodynamic…”
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Evidence for slab material under Greenland and links to Cretaceous High Arctic magmatism by Shephard, G. E., Trønnes, R. G., Spakman, W., Panet, I., Gaina, C.

“…Understanding the evolution of extinct ocean basins through time and space demands the integration of surface kinematics and mantle dynamics. We explore the…”
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Circum-Arctic mantle structure and long-wavelength topography since the Jurassic by Shephard, G. E., Flament, N., Williams, S., Seton, M., Gurnis, M., Müller, R. D.

“…The circum‐Arctic is one of the most tectonically complex regions of the world, shaped by a history of ocean basin opening and closure since the Early…”
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The T‐Reflection and the Deep Crustal Structure of the Vøring Margin, Offshore mid‐Norway by Abdelmalak, M. M., Faleide, J. I., Planke, S., Gernigon, L., Zastrozhnov, D., Shephard, G. E., Myklebust, R.

“…Seismic reflection data along volcanic passive margins frequently provide imaging of strong and laterally continuous reflections in the middle and lower crust…”
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Fibrin degradation product D-dimer induces the synthesis and release of biologically active IL-1 beta, IL-6 and plasminogen activator inhibitors from monocytes in vitro by Robson, S C, Shephard, E G, Kirsch, R E

“…Disseminated intravascular coagulation, characterized by circulating fibrin(ogen) degradation products (FDP), is associated with both acute and chronic…”
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Closure of the Mongol–Okhotsk Ocean: Insights from seismic tomography and numerical modelling by Fritzell, E.H., Bull, A.L., Shephard, G.E.

“…The existence of the Palaeozoic and Mesozoic Mongol–Okhotsk Ocean is evident from the Mongol–Okhotsk suture, which stretches from central Mongolia to the Sea…”
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P19-53 LB. Priming with recombinant BCG expressing HIV-1 Gag or RT and boosting with recombinant MVA induces an effective immune response in mice by Stutz, H, Powles, R, Shephard, EG, Williamson, A

“…Doc number: P417…”
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The immune response of the Chacma baboon to Bacille Calmette Guerin: development of a primate model for BCG-based vaccine research by Chege, G.K., Williamson, A.-L., Passmore, J.S., Bourn, W., Ryffel, B., Shephard, E.G.

“…Mycobacterium bovis Bacilli Calmette-Guerin (BCG) is used increasingly as an efficient vector for expression of recombinant proteins to induce a strong…”
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Geological, tomographic, kinematic and geodynamic constraints on the dynamics of sinking slabs by Butterworth, N.P., Talsma, A.S., Müller, R.D., Seton, M., Bunge, H.-P., Schuberth, B.S.A., Shephard, G.E., Heine, C.

“…•Global slab sinking rates approximate 13±3mm/yr.•Absolute reference frame choice dictates slab accumulation provinces.•Iterative geodynamic modeling can be…”
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Purification of and kinetic studies on a cloned protoporphyrinogen oxidase from the aerobic bacterium Bacillus subtilis by Corrigall, A V, Siziba, K B, Maneli, M H, Shephard, E G, Ziman, M, Dailey, T A, Dailey, H A, Kirsch, R E, Meissner, P N

“…The previously cloned and expressed protoporphyrinogen oxidase from Bacillus subtilis has been purified to homogeneity by Ni2+ affinity chromatography using a…”
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A novel high molecular weight fibrinogenase from the venom of Bitis arietans by Jennings, B.R, Spearman, C.W.N, Kirsch, R.E, Shephard, E.G

“…A fibrinogenase (Ba100) with an apparent molecular mass of 100 kDa under non-reducing conditions and a p I of 5.4 was purified from the venom of the African…”
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Role of neutrophil membrane proteases in fibrin degradation by Adams, S A, Kelly, S L, Kirsch, R E, Robson, S C, Shephard, E G

“…The cellular components of blood play a significant role in the breakdown of fibrin, with specific cellular adhesive processes allowing for accumulation of…”
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The role of microcystin-LR in the induction of apoptosis and oxidative stress in CaCo2 cells by Botha, Nicolette, Gehringer, Michelle M., Downing, Tim G., Venter, Maryna van de, Shephard, Enid G.

“…The increasing presence of toxic cyanobacteria in drinking and recreational water bodies, and their potential to impact on human and animal health is cause for…”
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C-reactive protein (CRP) peptides inactivate enolase in human neutrophils leading to depletion of intracellular ATP and inhibition of superoxide generation by SHEPHARD, E. G, ANDERSON, R, ROSEN, O, FRIDKIN, M

“…The nature and the biochemical mechanism of inhibition of neutrophil membrane-associated oxidative metabolism by two synthetic peptides p77-82 and p201-206…”
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Peptides generated from C-reactive protein by a neutrophil membrane protease. Amino acid sequence and effects of peptides on neutrophil oxidative metabolism and chemotaxis by Shephard, EG, Anderson, R, Rosen, O, Myer, MS, Fridkin, M, Strachan, AF, De Beer, FC

“…We have recently provided evidence that C-reactive protein (CRP) could act as an up-regulatable substrate for membrane-associated neutrophil serine…”
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Generation of biologically active C-reactive protein peptides by a neutral protease on the membrane of phorbol myristate acetate- stimulated neutrophils by Shephard, EG, Beer, SM, Anderson, R, Strachan, AF, Nel, AE, de Beer, FC

“…The association of human C-reactive protein (CRP) with nonstimulated and PMA-stimulated human neutrophils and the concomitant degradation of CRP (monitored by…”
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Digestion of 125I-labelled plasmin-derived fibrin degradation products by neutrophil lysosomal enzymes by Adams, S A, Kelly, S L, Kirsch, R E, Shephard, E G

“…The cellular components of the blood, which become associated with fibrin through specific cellular adhesive processes, play a significant role in the…”
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Characterization of neutrophil‐mediated degradation of human C‐reactive protein and identification of the protease by SHEPHARD, E. G., KELLY, S. L., ANDERSON, R., FRIDKIN, M.

“…SUMMARY Human C‐reactive protein (CRP) is shown to mediate a release of enzymatic activity from neutrophils which promotes its own degradation in the…”
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Lung function and plasma levels of thromboxane B2, 6‐ketoprostaglandin F1 alpha and beta‐thromboglobulin in antigen‐induced asthma before and after indomethacin pretreatment by Shephard, EG, Malan, L, Macfarlane, CM, Mouton, W, Joubert, JR

“…The effect of specific antigen challenge on the lung function of eight allergic asthmatic patients after placebo and indomethacin pretreatment has been…”
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