Search Results - "Sheperdigian, Adam"

Design and conduct of Xtreme Everest 2: An observational cohort study of Sherpa and lowlander responses to graduated hypobaric hypoxia [version 1; peer review: 2 approved] by Gilbert-Kawai, Edward, Sheperdigian, Adam, Adams, Thomas, Mitchell, Kay, Feelisch, Martin, Murray, Andrew, Peters, Mark, Gilbert-Kawai, Grace, Montgomery, Hugh, Levett, Denny, Kumar, Rajendra, Mythen, Michael, Grocott, Michael, Martin, Daniel

“…Objective: Oxygen availability falls with ascent to altitude and also as a consequence of critical illness. Because cellular sequelae and adaptive processes…”
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Dietary Nitrate Supplementation Does Not Alter Exercise Efficiency at High Altitude - Further Results From the Xtreme Alps Study by Hennis, Philip J, Cumpstey, Andrew F, O'Doherty, Alasdair F, Fernandez, Bernadette O, Gilbert-Kawai, Edward T, Mitchell, Kay, Moyses, Helen, Cobb, Alexandra, Meale, Paula, Pöhnl, Helmut, Mythen, Monty G, Grocott, Michael P W, Levett, Denny Z H, Martin, Daniel S, Feelisch, Martin

“…Nitrate supplementation in the form of beetroot juice (BRJ) ingestion has been shown to improve exercise tolerance during acute hypoxia, but its effect on…”
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Effects of dietary nitrate supplementation on microvascular physiology at 4559 m altitude – A randomised controlled trial (Xtreme Alps) by Cumpstey, Andrew F., Hennis, Philip J., Gilbert-Kawai, Edward T., Fernandez, Bernadette O., Grant, Daniel, Jenner, William, Poudevigne, Matthieu, Moyses, Helen, Levett, Denny ZH, Cobb, Alexandra, Meale, Paula, Mitchell, Kay, Pöhnl, Helmut, Mythen, Monty G., Grocott, Michael PW, Martin, Daniel S., Feelisch, Martin

“…Native highlanders (e.g. Sherpa) demonstrate remarkable hypoxic tolerance, possibly secondary to higher levels of circulating nitric oxide (NO) and increased…”
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Pushing arterial-venous plasma biomarkers to new heights: A model for personalised redox metabolomics? by Cumpstey, Andrew F, Minnion, Magdalena, Fernandez, Bernadette O, Mikus-Lelinska, Monika, Mitchell, Kay, Martin, Daniel S, Grocott, Michael P W, Feelisch, Martin

“…The chemical and functional interactions between Reactive Oxygen (ROS), Nitrogen (RNS) and Sulfur (RSS) species allow organisms to detect and respond to…”
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Systemic oxygen extraction during exercise at high altitude by Martin, D.S., Cobb, A., Meale, P., Mitchell, K., Edsell, M., Mythen, M.G., Grocott, M.P.W., Adams, Tom, Biseker, Lindsay, Booth, Adam, Burdall, Oliver, Cobb, Alexandra, Cumpstey, Andrew, Dauncey, Steve, Edsell, Mark, Farrant, James, Feelisch, Martin, Fernandez, Bernadette, Firth, Oliver, Gilbert, Edward, Grant, Daniel, Grocott, Michael, Hennis, Phil, Jackson, Laura, Jenner, Will, van der Kaaij, Jildou, Khosravi, Maryam, Kortekaas, Edith, Levett, Denny, Mahomed, Zeyn, Martin, Daniel, Meale, Paula, Milledge, Jim, Mitchell, Kay, Mole, Damian, Moses, Oliver, Mythen, Michael, Rigat, Fabio, O'Doherty, Alasdair, Salam, Alex, Sanborn, Matt, Sheperdigian, Adam, Shrubb, Fiona, Simpson, Jo, Talbot, Nick, Wandrag, Liesel, Wijesingha, Savini, Williamson, Wilby, Woolley, Tom, Yow, Heng

“…Classic teaching suggests that diminished availability of oxygen leads to increased tissue oxygen extraction yet evidence to support this notion in the context…”
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