Search Results - "Shepelev, Mikhail V"
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A New Chimeric Antibody against the HIV-1 Fusion Inhibitory Peptide MT-C34 with a High Affinity and Fc-Mediated Cellular Cytotoxicity
Published in Biology (Basel, Switzerland) (01-09-2024)“…Peptides from heptad repeat (HR1 and HR2) regions of gp41 are effective inhibitors of HIV-1 entry that block the fusion of viral and cellular membranes, but…”
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Production of hornless dairy cattle from genome-edited blastocysts
Published in E3S Web of Conferences (01-01-2020)“…Cattle of polled phenotype is convenient for breeders, as it decreases the risk of animals being hurt and ensures safety of workers. We developed the system…”
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A gel-less isolation of untagged plasmid DNA insert from vector backbone in homogeneous format
Published in Analytical biochemistry (15-03-2017)“…Agarose gel electrophoresis with subsequent DNA extraction from gel is routinely used for DNA fragment isolation after plasmid DNA digestion. We describe a…”
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Rho family GTPase Chp/RhoV induces PC12 apoptotic cell death via JNK activation
Published in Small GTPases (01-01-2011)“…Rho GTPases regulate numerous cellular processes including apoptosis. Chp/RhoV is an atypical Rho GTPase which functions are poorly understood. Here we…”
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The RHOV gene is overexpressed in human non–small cell lung cancer
Published in Cancer genetics (01-11-2013)“…Rho family GTPases act as molecular switches to regulate numerous cellular processes, including malignant transformation. Commonly, overexpression of Rho…”
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hTERT and BIRC5 gene promoters for cancer gene therapy: A comparative study
Published in Oncology letters (01-08-2016)“…Human telomerase reverse transcriptase (hTERT) and survivin (BIRC5) gene promoters are frequently used for transcriptional targeting of tumor cells, yet there…”
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LY294002 Enhances Expression of Proteins Encoded by Recombinant Replication-Defective Adenoviruses via mTOR- and Non-mTOR-Dependent Mechanisms
Published in Molecular pharmaceutics (04-03-2013)“…Adenovirus-based drugs are efficient when combined with other anticancer treatments. Here we show that treatment with LY294002 and LY303511 upregulates…”
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