Search Results - "Shentu, Xinyi"
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BCAA Catabolic Defect Alters Glucose Metabolism in Lean Mice
Published in Frontiers in physiology (04-09-2019)“…Recent studies show branched-chain amino acid (BCAA) catabolic pathway is defective in obese animals and humans, contributing to the pathogenesis of insulin…”
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Point mutations of homologs as an adaptive solution to the gene loss
Published in Journal of genetics and genomics (01-07-2023)“…Gene loss is common and influences genome evolution trajectories. Multiple adaptive strategies to compensate for gene loss have been observed, including copy…”
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A spatiotemporal atlas of cholestatic injury and repair in mice
Published in Nature genetics (01-05-2024)“…Cholestatic liver injuries, characterized by regional damage around the bile ductular region, lack curative therapies and cause considerable mortality. Here we…”
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A spatiotemporal atlas of mouse liver homeostasis and regeneration
Published in Nature genetics (01-05-2024)“…The mechanism by which mammalian liver cell responses are coordinated during tissue homeostasis and perturbation is poorly understood, representing a major…”
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