Search Results - "Shenk, Jennifer L"

A Selective Peroxisome Proliferator-Activated Receptor δ Agonist Promotes Reverse Cholesterol Transport by Oliver, William R., Shenk, Jennifer L., Snaith, Mike R., Russell, Caroline S., Plunket, Kelli D., Bodkin, Noni L., Lewis, Michael C., Winegar, Deborah A., Sznaidman, Marcos L., Lambert, Millard H., Xu, H. Eric, Sternbach, Daniel D., Kliewer, Steven A., Hansen, Barbara C., Willson, Timothy M.

“…The peroxisome proliferator-activated receptors (PPARs) are dietary lipid sensors that regulate fatty acid and carbohydrate metabolism. The hypolipidemic…”
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Functional Consequences of Cysteine Modification in the Ligand Binding Sites of Peroxisome Proliferator Activated Receptors by GW9662 by Leesnitzer, Lisa M, Parks, Derek J, Bledsoe, Randy K, Cobb, Jeff E, Collins, Jon L, Consler, Thomas G, Davis, Roderick G, Hull-Ryde, Emily A, Lenhard, James M, Patel, Lisa, Plunket, Kelli D, Shenk, Jennifer L, Stimmel, Julie B, Therapontos, Christina, Willson, Timothy M, Blanchard, Steven G

“…In the course of a high throughput screen to search for ligands of peroxisome proliferator activated receptor-γ (PPARγ), we identified GW9662 using a…”
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The Pregnane X Receptor: A Promiscuous Xenobiotic Receptor That Has Diverged during Evolution by Jones, Stacey A, Moore, Linda B, Shenk, Jennifer L, Wisely, G. Bruce, Hamilton, Geraldine A, McKee, David D, Tomkinson, Nicholas C. O, LeCluyse, Edward L, Lambert, Millard H, Willson, Timothy M, Kliewer, Steven A, Moore, John T

“…Transcription of genes encoding cytochrome P450 3A (CYP3A) monooxygenases is induced by a variety of xenobiotics and natural steroids. There are marked…”
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p53 Represses Androgen-induced Transactivation of Prostate-specific Antigen by Disrupting hAR Amino- to Carboxyl-terminal Interaction by Shenk, Jennifer L., Fisher, Christopher J., Chen, Shao-Yong, Zhou, Xiao-Feng, Tillman, Karl, Shemshedini, Lirim

“…Prostate-specific antigen (PSA) is highly overexpressed in prostate cancer. One important regulator ofPSA expression is the androgen receptor (AR), the nuclear…”
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