Search Results - "Shen, Yunheng"
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Berberine regulates the Notch1/PTEN/PI3K/AKT/mTOR pathway and acts synergistically with 17-AAG and SAHA in SW480 colon cancer cells
Published in Pharmaceutical biology (01-01-2021)“…Berberine (BBR) is used to treat diarrhoea and gastroenteritis in the clinic. It was found to have anticolon cancer effects. To study the anticolon cancer…”
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2
Delavatine A Attenuates OGD/R-Caused PC12 Cell Injury and Apoptosis through Suppressing the MKK7/JNK Signaling Pathway
Published in Biological & pharmaceutical bulletin (01-12-2022)“…Delavatine A (DA) is an unusual isoquinoline alkaloid with a novel skeleton isolated from Chinese folk medicine Incarvillea delavayi. Studies conducted in our…”
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3
Astragalus polysaccharide ameliorated complex factor-induced chronic fatigue syndrome by modulating the gut microbiota and metabolites in mice
Published in Biomedicine & pharmacotherapy (01-07-2023)“…Chronic fatigue syndrome (CFS) is a debilitating disease with no symptomatic treatment. Astragalus polysaccharide (APS), a component derived from the…”
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4
Integrated transcriptomic and metabolomic profiles reveal the protective mechanism of modified Danggui Buxue decoction on radiation-induced leukopenia in mice
Published in Frontiers in pharmacology (03-08-2023)“…Leukopenia caused by radiation hinders the continuous treatment of cancers. Danggui Buxue Decoction (DBD) has been widely used in clinical owing to low…”
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5
Identification of anti-tumor constituents from toad skin and toad venom by UPLC-QTOF/MS in-depth chemical profiling combined with bioactivity-based molecular networking
Published in Arabian journal of chemistry (01-01-2024)“…Toad skin (TS) and toad venom (TV) are two different traditional Chinese medicine (TCM) prepared from Bufo bufo gargarizans Cantor and Bufo melanostictus…”
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6
Characterization and Discrimination of Ophiopogonis Radix with Different Levels of Sulfur Fumigation Based on UPLC-QTOF-MS Combined Molecular Networking with Multivariate Statistical Analysis
Published in Metabolites (30-01-2023)“…Ophiopogonis Radix, also known as "Maidong" (MD) in China, is frequently sulfur-fumigated (SF) in the pretreatment process of MD to improve the appearance and…”
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7
Narciclasine targets STAT3 via distinct mechanisms in tamoxifen-resistant breast cancer cells
Published in Molecular therapy. Oncolytics (17-03-2022)“…STAT3 is constitutively activated in multiple malignant tumors. Compared with regular estrogen receptor (ER)-positive breast cancers, the patients with…”
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Sesquiterpene lactones from Inula falconeri, a plant endemic to the Himalayas, as potential anti-inflammatory agents
Published in European journal of medicinal chemistry (01-11-2011)“…A phytochemical investigation of Inula falconeri, a plant endemic to the Himalayas, afforded 10 new sesquiterpenoids and 26 known sesquiterpene lactones,…”
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9
Comprehensive Metabolic Profiling of Euphorbiasteroid in Rats by Integrating UPLC-Q/TOF-MS and NMR as Well as Microbial Biotransformation
Published in Metabolites (01-09-2022)“…Euphorbiasteroid, a lathyrane-type diterpene from Euphorbiae semen (the seeds of Euphorbia lathyris L.), has been shown to have a variety of pharmacological…”
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10
Distinctive effect on nerve growth factor-induced PC12 cell neurite outgrowth by two unique neolignan enantiomers from Illicium merrillianum
Published in Scientific reports (20-11-2015)“…Merrillianoid ( 1 ), a racemic neolignan possessing the characteristic benzo-2,7-dioxabicyclo[3.2.1]octane moiety, was isolated from the branches and leaves of…”
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11
Triterpenoids from two Terminalia species
Published in Planta medica (01-10-2010)“…Phytochemical investigations of Terminalia arjuna bark and Terminalia chebula fruits resulted in the isolation of twelve triterpenoids including two new…”
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Anti-inflammatory and anti-nociceptive activities of compounds from Tinospora sagittata (Oliv.) Gagnep
Published in Archives of pharmacal research (01-07-2010)“…Radix Tinosporae is a herb widely used in traditional Chinese medicine for the treatment of various inflammatory diseases. In the present study, its…”
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13
Carboline alkaloids from Psammosilene tunicoides and their cytotoxic activities
Published in Planta medica (01-04-2012)“…Five new carboline alkaloids, tunicoidines A-E ( 1- 5), and two known carboline alkaloids, 1-acetyl-β-carboline-3-carboxylic acid ( 6) and…”
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18,19-secooleanane type triterpene glycosyl esters from the bark of Terminalia arjuna
Published in Planta medica (01-06-2010)“…Five novel 18,19-secooleanane-type triterpene glycosyl esters, namely arjunasides A-E, were isolated from the MeOH extract of the bark of Terminalia arjuna…”
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Simultaneous analysis of flavonoids from Hypericum japonicum Thunb.ex Murray (Hypericaceae) by HPLC-DAD–ESI/MS
Published in Journal of pharmaceutical and biomedical analysis (22-01-2008)“…A novel and sensitive HPLC-UV method has been developed for the simultaneous determination of five major flavonoids in Hypericum japonicum hydroalcoholic…”
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16
Four Novel Nortriterpenoids Isolated from Schisandra henryi var. yunnanensis
Published in European journal of organic chemistry (01-02-2004)“…Four novel nortriterpenoids, henridilactones A−D (1−4), members of a very rare highly oxidized cycloartane skeletal class with a biosynthetically modified…”
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N-containing compounds from the traditional Chinese medicine ChanSu
Published in Chemistry of natural compounds (01-07-2009)Get full text
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18
Quantitative LC/MS/MS method and in vivo pharmacokinetic studies of vitexin rhamnoside, a bioactive constituent on cardiovascular system from hawthorn
Published in Biomedical chromatography (01-04-2007)“…A simple and accurate liquid chromatography coupled with tandem mass spectrometry method was developed for determination and in vivo pharmacokinetic studies of…”
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Studies on the chemical constituents of Daphne pedunculata
Published in Chemistry of natural compounds (01-11-2008)Get full text
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20
A distributed joint extraction framework for sedimentological entities and relations with federated learning
Published in Expert systems with applications (01-03-2023)“…Sedimentological knowledge graphs can be used to identify natural resources in earth layers, which may help geologists analyze the distribution of oil crude in…”
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