Search Results - "Shen, Youqing"

Rational Design of Cancer Nanomedicine: Nanoproperty Integration and Synchronization by Sun, Qihang, Zhou, Zhuxian, Qiu, Nasha, Shen, Youqing

“…Current cancer nanomedicines can only mitigate adverse effects but fail to enhance therapeutic efficacies of anticancer drugs. Rational design of…”
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Preparation, surface functionalization and application of Fe3O4 magnetic nanoparticles by Liu, Shixiang, Yu, Bing, Wang, Song, Shen, Youqing, Cong, Hailin

“…This paper reviews recent developments in the preparation, surface functionalization, and applications of Fe3O4 magnetic nanoparticles. Especially, it includes…”
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Challenges in design of translational nanocarriers by Sun, Qihang, Radosz, Maciej, Shen, Youqing

“…Cancer drug delivery achieving high therapeutic efficacy and low side effects requires a nanocarrier to tightly retain the drug, efficiently reach the tumor,…”
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The Blood Clearance Kinetics and Pathway of Polymeric Micelles in Cancer Drug Delivery by Sun, Xuanrong, Wang, Guowei, Zhang, Hao, Hu, Shiqi, Liu, Xin, Tang, Jianbin, Shen, Youqing

“…Polymer micelles are one of the most investigated nanocarriers for drug delivery; many have entered clinical trials and some are in clinic use, but their…”
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Co-delivery of IOX1 and doxorubicin for antibody-independent cancer chemo-immunotherapy by Liu, Jing, Zhao, Zhihao, Qiu, Nasha, Zhou, Quan, Wang, Guowei, Jiang, Haiping, Piao, Ying, Zhou, Zhuxian, Tang, Jianbin, Shen, Youqing

“…Anti-programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) antibodies are currently used in the clinic to interupt the PD-1/PD-L1 immune…”
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The tumor EPR effect for cancer drug delivery: Current status, limitations, and alternatives by Sun, Rui, Xiang, Jiajia, Zhou, Quan, Piao, Ying, Tang, Jianbin, Shao, Shiqun, Zhou, Zhuxian, Bae, You Han, Shen, Youqing

“…[Display omitted] Over the past three decades, the enhanced permeability and retention (EPR) effect has been considered the basis of tumor-targeted drug…”
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Application of multifunctional BODIPY in photodynamic therapy by Zhang, Wangquan, Ahmed, Adeel, Cong, Hailin, Wang, Song, Shen, Youqing, Yu, Bing

“…At present, BODIPY and its derivatives are a kind of multifunctional photosensitive organic dyes, because of their small Stokes shift, strong absorption,…”
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A Tumor‐Specific Cascade Amplification Drug Release Nanoparticle for Overcoming Multidrug Resistance in Cancers by Ye, Mingzhou, Han, Yuxin, Tang, Jianbin, Piao, Ying, Liu, Xiangrui, Zhou, Zhuxian, Gao, Jianqing, Rao, Jianghong, Shen, Youqing

“…A cascade amplification release nanoparticle (CARN) is constructed by the coencapsulation of β‐lapachone and a reactive‐oxygen‐species (ROS)‐responsive…”
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Nonviral cancer gene therapy: Delivery cascade and vector nanoproperty integration by Zhou, Zhuxian, Liu, Xiangrui, Zhu, Dingcheng, Wang, Yue, Zhang, Zhen, Zhou, Xuefei, Qiu, Nasha, Chen, Xuesi, Shen, Youqing

“…Gene therapy represents a promising cancer treatment featuring high efficacy and limited side effects, but it is stymied by a lack of safe and efficient…”
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The Role of Micelle Size in Tumor Accumulation, Penetration, and Treatment by Wang, Jinqiang, Mao, Weiwei, Lock, Lye Lin, Tang, Jianbin, Sui, Meihua, Sun, Weilin, Cui, Honggang, Xu, Dong, Shen, Youqing

“…The specific sizes that determine optimal nanoparticle tumor accumulation, penetration, and treatment remain inconclusive because many studies compared…”
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Fabrication of micellar nanoparticles for drug delivery through the self-assembly of block copolymers by Tyrrell, Zachary L., Shen, Youqing, Radosz, Maciej

“…Micelles formed through the self-assembly of block copolymers have been widely used to encapsulate highly hydrophobic drugs to increase their effective…”
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In Vivo and in Situ Tracking Cancer Chemotherapy by Highly Photostable NIR Fluorescent Theranostic Prodrug by Wu, Xumeng, Sun, Xuanrong, Guo, Zhiqian, Tang, Jianbin, Shen, Youqing, James, Tony D, Tian, He, Zhu, Weihong

“…In vivo monitoring of the biodistribution and activation of prodrugs is urgently required. Near infrared (NIR) fluorescence-active fluorophores with excellent…”
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Active Transportation of Liposome Enhances Tumor Accumulation, Penetration, and Therapeutic Efficacy by Wang, Guowei, Wu, Bihan, Li, Qunying, Chen, Siqin, Jin, Xiaoqin, Liu, Yajing, Zhou, Zhuxian, Shen, Youqing, Huang, Pintong

“…Liposomes are the first and mostly explored nanocarriers for cancer drug delivery, which have shown great promise in clinical applications, but their limited…”
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Transcytosis-enabled active extravasation of tumor nanomedicine by Zhou, Quan, Li, Junjun, Xiang, Jiajia, Shao, Shiqun, Zhou, Zhuxian, Tang, Jianbin, Shen, Youqing

“…Nanomedicines can extravasate from tumor vascular lumen into solid tumors via the EPR effect (a) or transcytosis (b). Transcytosis can be further…”
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Biocompatible Cyclodextrin-Based Metal–Organic Frameworks for Long-Term Sustained Release of Fragrances by Zhang, Bo, Huang, Jianxiang, Liu, Kexin, Zhou, Zhuxian, Jiang, Liming, Shen, Youqing, Zhao, Dan

“…The encapsulation of volatile fragrances within porous materials is capable of increasing their stability for long-term controlled release; however, the…”
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Tumor extravasation and infiltration as barriers of nanomedicine for high efficacy: The current status and transcytosis strategy by Zhou, Quan, Dong, Chengyuan, Fan, Wufa, Jiang, Haiping, Xiang, Jiajia, Qiu, Nasha, Piao, Ying, Xie, Tao, Luo, Yingwu, Li, Zichen, Liu, Fusheng, Shen, Youqing

“…Nanotechnology-based drug delivery platforms have been explored for cancer treatments and resulted in several nanomedicines in clinical uses and many in…”
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Application and design of esterase-responsive nanoparticles for cancer therapy by Dong, Haonan, Pang, Long, Cong, Hailin, Shen, Youqing, Yu, Bing

“…Nanoparticles have been developed for tumor treatment due to the enhanced permeability and retention effects. However, lack of specific cancer cells…”
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Recent Progress in Fluorescence Imaging of the Near‐Infrared II Window by Miao, Yawei, Gu, Chuantao, Zhu, Yaowei, Yu, Bing, Shen, Youqing, Cong, Hailin

“…Near‐infrared (NIR) fluorescent materials are considered to be the most promising labeling reagents for sensitive determination and biological imaging due to…”
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Nuclear drug delivery for cancer chemotherapy by Sui, Meihua, Liu, Wenwen, Shen, Youqing

“…Nanosystems with unique physical and biological properties have been extensively explored for cancer targeted intracellular delivery of small-molecular…”
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Macromolecular MRI contrast agents: Structures, properties and applications by Tang, Jianbin, Sheng, Yuqi, Hu, Hongjie, Shen, Youqing

“…Stable gadolinium chelates are widely used as the contrast agents (CAs) for magnetic resonance imaging (MRI). Conjugation of the chelates onto macromolecular…”
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