Search Results - "Shen, Weiyan"
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Inflammation, epigenetics, and metabolism converge to cell senescence and ageing: the regulation and intervention
Published in Signal transduction and targeted therapy (28-06-2021)“…Remarkable progress in ageing research has been achieved over the past decades. General perceptions and experimental evidence pinpoint that the decline of…”
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A Multi-Scale Spatial Attention Region Proposal Network for High-Resolution Optical Remote Sensing Imagery
Published in Remote sensing (Basel, Switzerland) (01-09-2021)“…Deep convolutional neural networks (DCNNs) are driving progress in object detection of high-resolution remote sensing images. Region proposal generation, as…”
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Effect of Metformin on Cardiac Metabolism and Longevity in Aged Female Mice
Published in Frontiers in cell and developmental biology (26-01-2021)“…The antidiabetic drug metformin exerts pleiotropic effects on multiple organs, including the cardiovascular system. Evidence has shown that metformin improves…”
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Nicotinamide adenine dinucleotide replenishment rescues colon degeneration in aged mice
Published in Signal transduction and targeted therapy (07-07-2017)“…Susceptibility of gastrointestinal dysmotility increases with age-associated colonic degeneration. A paucity of remedies reversing colonic degeneration per se…”
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Fine-Tuning of PGC1α Expression Regulates Cardiac Function and Longevity
Published in Circulation research (13-09-2019)“…RATIONALE:PGC1α (peroxisome proliferator-activated receptor gamma coactivator 1α) represents an attractive target interfering bioenergetics and mitochondrial…”
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PGC1α protects against hepatic steatosis and insulin resistance via enhancing IL10‐mediated anti‐inflammatory response
Published in The FASEB journal (01-08-2020)“…Inflammatory responses are pivotal incidences in hepatic metabolic derangements. However, the underlying mechanism remains elusive. The present study aimed to…”
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