Search Results - "Shen, Peiye"

SOX17 and PAX8 constitute an actionable lineage-survival transcriptional complex in ovarian cancer by Lin, Lifeng, Shi, Kaixuan, Zhou, Shaoqing, Cai, Mei-Chun, Zhang, Caiyan, Sun, Yunheng, Zang, Jingyu, Cheng, Lin, Ye, Kaiyan, Ma, Pengfei, Shen, Peiye, Zhang, Meiying, Cheng, Yan, Qi, Chunting, Li, Ying, Yin, Xia, Zheng, Yiyan, Tan, Li, Zhuang, Guanglei, Zang, Rongyu

“…Müllerian tissue-specific oncogenes, prototyped by PAX8, underlie ovarian tumorigenesis and represent unique molecular vulnerabilities. Further delineating…”
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Autophagy activation attenuates angiotensin II-induced cardiac fibrosis by Liu, Shenglan, Chen, Shaorui, Li, Min, Zhang, Boyu, Shen, Peiye, Liu, Peiqing, Zheng, Dandan, Chen, Yijie, Jiang, Jianmin

“…Autophagy has been involved in numerous diseases processes. However, little is known about the role of autophagy in cardiac fibrosis. Thus, whether or not…”
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SIRT6 suppresses phenylephrine-induced cardiomyocyte hypertrophy though inhibiting p300 by Shen, Peiye, Feng, Xiaojun, Zhang, Xiaoying, Huang, Xiaoyang, Liu, Shenglan, Lu, Xia, Li, Jingyan, You, Jia, Lu, Jing, Li, Zhuoming, Ye, Jiantao, Liu, Peiqing

“…SIRT6 is a member of the sirtuin family of class III histone deacetylases. It plays important roles in regulating genomic stability, metabolism, stress…”
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PKCζ interacts with STAT3 and promotes its activation in cardiomyocyte hypertrophy by Li, Jingyan, Gao, Hui, Huang, Junying, Wang, Panxia, Huang, Yi, Luo, Wenwei, Zhang, Xiaoying, Shen, Peiye, You, Jia, Cai, Sidong, Li, Zhuoming, Liu, Peiqing

“…This study was aimed to investigate the crosstalk between protein kinase C ζ (PKCζ) and signal transducer and activator of transcription 3 (STAT3) in…”
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Hybrid sequencing-based personal full-length transcriptomic analysis implicates proteostatic stress in metastatic ovarian cancer by Jing, Ying, Zhang, Yi, Zhu, Hui, Zhang, Ke, Cai, Mei-Chun, Ma, Pengfei, Shen, Peiye, Zhang, Zhenfeng, Shao, Minghui, Wang, Jing, Yu, Minhua, Yin, Xia, Zhang, Meiying, Hu, Yuan, Chen, Danni, Di, Wen, Wang, Xiaojie, Zhuang, Guanglei

“…Comprehensive molecular characterization of myriad somatic alterations and aberrant gene expressions at personal level is key to precision cancer therapy, yet…”
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Comprehensive genomic profiling of neuroendocrine bladder cancer pinpoints molecular origin and potential therapeutics by Shen, Peiye, Jing, Ying, Zhang, Ruiyun, Cai, Mei-Chun, Ma, Pengfei, Chen, Haige, Zhuang, Guanglei

“…Neuroendocrine bladder cancer is a relatively rare but often lethal malignancy, with cell of origin, oncogenomic architecture and standard treatment poorly…”
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Genomic profiling and immune phenotyping of neuroendocrine bladder cancer by Zang, Jingyu, Shahatiaili, Akezhouli, Cai, Mei-Chun, Jin, Di, Shen, Peiye, Qian, Lei, Zhang, Lu, Zhang, Tianxiang, Wu, Yuchen, Yang, Fan, Wu, Zheng, Hou, Yanli, Bai, Yongrui, Xia, Jun, Cheng, Liang, Zhang, Ruiyun, Zhuang, Guanglei, Chen, Haige

“…Neuroendocrine bladder cancer (NEBC) poses a formidable clinical challenge and attracts keen interests to explore immunotherapy as a viable treatment option…”
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TIEG1 Inhibits Angiotensin II–induced Cardiomyocyte Hypertrophy by Inhibiting Transcription Factor GATA4 by Li, Qin, Shen, Peiye, Zeng, Siyu, Liu, Peiqing

“…The transforming growth factor (TGF-β)–inducible early gene (TIEG1), a member of the Sp1/Krüppel-like family of transcription factors, plays an important role…”
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STAT3 Suppression Is Involved in the Protective Effect of SIRT6 Against Cardiomyocyte Hypertrophy by Zhang, Xiaoying, Li, Wei, Shen, Peiye, Feng, Xiaojun, Yue, Zhongbao, Lu, Jing, You, Jia, Li, Jingyan, Gao, Hui, Fang, Shi, Li, Zhuoming, Liu, Peiqing

“…The activation of signal transducer and activator of transcription 3 (STAT3) is critical for the development of cardiac hypertrophy and heart failure. Sirtuin…”
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Therapeutic targeting of CPSF3-dependent transcriptional termination in ovarian cancer by Shen, Peiye, Ye, Kaiyan, Xiang, Huaijiang, Zhang, Zhenfeng, He, Qinyang, Zhang, Xiao, Cai, Mei-Chun, Chen, Junfei, Sun, Yunheng, Lin, Lifeng, Qi, Chunting, Zhang, Meiying, Cheung, Lydia W. T., Shi, Tingyan, Yin, Xia, Li, Ying, Di, Wen, Zang, Rongyu, Tan, Li, Zhuang, Guanglei

“…Transcriptional dysregulation is a recurring pathogenic hallmark and an emerging therapeutic vulnerability in ovarian cancer. Here, we demonstrated that…”
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Epigenetic heterogeneity promotes acquired resistance to BET bromodomain inhibition in ovarian cancer by Sun, Yunheng, Zhang, Zhenfeng, Zhang, Ke, Liu, Yuxia, Shen, Peiye, Cai, Meichun, Jia, Chenqiang, Wang, Wenjing, Gu, Zhuowei, Ma, Pengfei, Lu, Huaiwu, Guan, Lei, Di, Wen, Zhuang, Guanglei, Yin, Xia

“…BET bromodomain inhibitors (BETi) are promising therapeutic regimens for epithelial ovarian cancer (EOC). However, early-stage clinical trials indicate that…”
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