Search Results - "Shen, Ning"
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Correction: Genome Med 15, 115 & Genome Med 16, 3
Published in Genome medicine (14-05-2024)Get full text
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Inflammatory markers in Alzheimer’s disease and mild cognitive impairment: a meta-analysis and systematic review of 170 studies
Published in Journal of neurology, neurosurgery and psychiatry (01-05-2019)“…ObjectiveInflammation plays a crucial role in the pathogenesis of mild cognitive impairment (MCI) and Alzheimer’s disease (AD). Our study aimed to analyse…”
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On the modularity of 2-adic potentially semi-stable deformation rings
Published in Mathematische Zeitschrift (01-06-2021)“…Using p -adic local Langlands correspondence for GL 2 ( Q 2 ) and an ordinary R = T theorem, we prove that the support of patched modules for quaternionic…”
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Amyloid-β42/40 ratio drives tau pathology in 3D human neural cell culture models of Alzheimer’s disease
Published in Nature communications (13-03-2020)“…The relationship between amyloid-β (Aβ) species and tau pathology in Alzheimer’s disease (AD) is not fully understood. Here, we provide direct evidence that…”
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5
Soluble uric acid increases PDZK1 and ABCG2 expression in human intestinal cell lines via the TLR4-NLRP3 inflammasome and PI3K/Akt signaling pathway
Published in Arthritis research & therapy (07-02-2018)“…In addition to the kidney, the intestine is one of the most important organs involved in uric acid excretion. However, the mechanism of urate excretion in the…”
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The MDA-9/Syntenin/IGF1R/STAT3 Axis Directs Prostate Cancer Invasion
Published in Cancer research (Chicago, Ill.) (01-06-2018)“…Although prostate cancer is clinically manageable during several stages of progression, survival is severely compromised once cells invade and metastasize to…”
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System design effects on online impulse buying
Published in Internet research (10-08-2012)“…Purpose - Integrating the two-system (reflective vs. impulsive) model and the "stimulus-organism-response" framework, the purpose of this paper is to construct…”
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Option Pricing using Quantum Computers
Published in Quantum (Vienna, Austria) (06-07-2020)“…We present a methodology to price options and portfolios of options on a gate-based quantum computer using amplitude estimation, an algorithm which provides a…”
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Lumenal Galectin-9-Lamp2 interaction regulates lysosome and autophagy to prevent pathogenesis in the intestine and pancreas
Published in Nature communications (27-08-2020)“…Intracellular galectins are carbohydrate-binding proteins capable of sensing and repairing damaged lysosomes. As in the physiological conditions glycosylated…”
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Proteome-wide mapping of short-lived proteins in human cells
Published in Molecular cell (18-11-2021)“…Rapid protein degradation enables cells to quickly modulate protein abundance. Dysregulation of short-lived proteins plays essential roles in disease…”
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Remdesivir in treating hospitalized patients with COVID-19: A renewed review of clinical trials
Published in Frontiers in pharmacology (08-09-2022)“…Since December 2019, COVID-19 has spread across the world almost through 2.5 years. As of 16 June 2022, the cumulative number of confirmed cases of COVID-19…”
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Addressing Unmet Clinical Needs with 3D Printing Technologies
Published in Advanced healthcare materials (01-09-2018)“…Recent advances in 3D printing have enabled the creation of novel 3D constructs and devices with an unprecedented level of complexity, properties, and…”
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Blood biomarkers for the diagnosis of amnestic mild cognitive impairment and Alzheimer’s disease: A systematic review and meta-analysis
Published in Neuroscience and biobehavioral reviews (01-09-2021)“…•Blood Aβ42, Aβ40 and Aβ ratio using IMR technique have great AD diagnostic values.•Blood T-tau and P-tau 181 were increased from controls to aMCI to AD…”
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Longitudinal plasma phosphorylated tau 181 tracks disease progression in Alzheimer’s disease
Published in Translational psychiatry (12-06-2021)“…To assess plasma phosphorylated tau181 (p-tau181) as a progression biomarker in Alzheimer’s disease (AD), we examined longitudinal plasma p-tau181 of 1184…”
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Hydrogen Atom Transfer for C(sp3)−H Functionalization Enabled by Photoredox/Thianthrene/Methanol Synergistic Catalysis
Published in ChemCatChem (09-06-2023)“…A synergetic catalytic system of organophotocatalyst 4CzIPN, thianthrene, and methanol was developed for visible‐light‐induced Giese reactions of various…”
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Dynamic changes of CSF sTREM2 in preclinical Alzheimer's disease: the CABLE study
Published in Molecular neurodegeneration (10-04-2020)“…Loss of function of triggering receptor expressed on myeloid cell 2 (TREM2), a key receptor selectively expressed by microglia in the brain, contributes to the…”
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Quantitative modeling of transcription factor binding specificities using DNA shape
Published in Proceedings of the National Academy of Sciences - PNAS (14-04-2015)“…DNA binding specificities of transcription factors (TFs) are a key component of gene regulatory processes. Underlying mechanisms that explain the highly…”
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China's long march to malaria elimination: a case of adaptive management
Published in Malaria journal (08-02-2022)“…Since the 1950s, China has transitioned from a malaria pandemic country with tens of millions of annual cases, through phases of local control and elimination,…”
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Human pancreatic neuro-insular network in health and fatty infiltration
Published in Diabetologia (2018)“…Aims/hypothesis Identification of a pancreatic neuro-insular network in mice suggests that a similar integration of islets and nerves may be present in the…”
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MDA-9/Syntenin regulates protective autophagy in anoikis-resistant glioma stem cells
Published in Proceedings of the National Academy of Sciences - PNAS (29-05-2018)“…Glioma stem cells (GSCs) comprise a small subpopulation of glioblastoma multiforme cells that contribute to therapy resistance, poor prognosis, and tumor…”
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