Search Results - "Shen, Minhong"

Corroborating evidence for platelet-induced epithelial-mesenchymal transition and fibroblast-to-myofibroblast transdifferentiation in the development of adenomyosis by Liu, Xishi, Shen, Minhong, Qi, Qiuming, Zhang, Hongqi, Guo, Sun-Wei

“…Abstract STUDY QUESTION Do platelets play any role in the development of adenomyosis? SUMMARY ANSWER As in endometriosis, adenomyotic lesions show…”
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Complex interplay between tumor microenvironment and cancer therapy by Shen, Minhong, Kang, Yibin

“…Tumor microenvironment (TME) is comprised of cellular and non-cellular components that exist within and around the tumor mass. The TME is highly dynamic and…”
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PKD1 Phosphorylation-Dependent Degradation of SNAIL by SCF-FBXO11 Regulates Epithelial-Mesenchymal Transition and Metastasis by Zheng, Hanqiu, Shen, Minhong, Zha, Yin-Lian, Li, Wenyang, Wei, Yong, Blanco, Mario Andres, Ren, Guangwen, Zhou, Tianhua, Storz, Peter, Wang, Hui-Yun, Kang, Yibin

“…Metastatic dissemination is often initiated by the reactivation of an embryonic development program referred to as epithelial-mesenchymal transition (EMT). The…”
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Tinagl1 Suppresses Triple-Negative Breast Cancer Progression and Metastasis by Simultaneously Inhibiting Integrin/FAK and EGFR Signaling by Shen, Minhong, Jiang, Yi-Zhou, Wei, Yong, Ell, Brian, Sheng, Xinlei, Esposito, Mark, Kang, Jooeun, Hang, Xiang, Zheng, Hanqiu, Rowicki, Michelle, Zhang, Lanjing, Shih, Weichung J., Celià-Terrassa, Toni, Liu, Yirong, Cristea, IIeana, Shao, Zhi-Ming, Kang, Yibin

“…Triple-negative breast cancer (TNBC) patients have the worst prognosis and distant metastasis-free survival among all major subtypes of breast cancer. The poor…”
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Deubiquitinase USP20 promotes breast cancer metastasis by stabilizing SNAI2 by Li, Wenyang, Shen, Minhong, Jiang, Yi-Zhou, Zhang, Ruina, Zheng, Hanqiu, Wei, Yong, Shao, Zhi-Ming, Kang, Yibin

“…SNAI2/SLUG, a metastasis-promoting transcription factor, is a labile protein that is degraded through the ubiquitin proteasome degradation system. Here, we…”
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Tumor Microenvironment Shapes Colorectal Cancer Progression, Metastasis, and Treatment Responses by Li, Jun, Chen, Dawei, Shen, Minhong

“…Colorectal cancer (CRC) is one of the most devastating diseases that accounts for numerous deaths worldwide. Tumor cell-autonomous pathways, such as the…”
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Therapeutic Targeting of Metadherin Suppresses Colorectal and Lung Cancer Progression and Metastasis by Shen, Minhong, Xie, Shanshan, Rowicki, Michelle, Michel, Sven, Wei, Yong, Hang, Xiang, Wan, Liling, Lu, Xin, Yuan, Min, Jin, John F, Jaschinski, Frank, Zhou, Tianhua, Klar, Richard, Kang, Yibin

“…Colorectal and lung cancers account for one-third of all cancer-related deaths worldwide. Previous studies suggested that metadherin (MTDH) is involved in the…”
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MTDH-SND1 Interaction Is Crucial for Expansion and Activity of Tumor-Initiating Cells in Diverse Oncogene- and Carcinogen-Induced Mammary Tumors by Wan, Liling, Lu, Xin, Yuan, Salina, Wei, Yong, Guo, Feng, Shen, Minhong, Yuan, Min, Chakrabarti, Rumela, Hua, Yuling, Smith, Heath A., Blanco, Mario Andres, Chekmareva, Marina, Wu, Hao, Bronson, Roderick T., Haffty, Bruce G., Xing, Yongna, Kang, Yibin

“…The Metadherin gene (MTDH) is prevalently amplified in breast cancer and associated with poor prognosis; however, its functional contribution to tumorigenesis…”
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Effects of an Oral Multi-vitamin Carbohydrate Beverage on Intraoperative Nausea and Vomiting in Women Converted from Vaginal Delivery to Cesarean Section by Xu, Jinli, Shen, Minhong, Shen, Jie, Han, Bing, Huang, Qin, Chen, Youguo

“…Background: Nausea and vomiting are common and unpleasant symptoms for pregnant women during cesarean section, which can lead to aspiration, a serious…”
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Development and Validation of Models to Predict Cesarean Delivery among Low-Risk Nulliparous Women at Term: A Retrospective Study in China by Sun, Fangcan, Wu, Fangfang, Chen, Huiyun, Shen, Qianqian, Chen, Youguo, Shen, Minhong, Han, Bing

“…Background: Intrapartum cesarean delivery has been the focus of many researchers. We derived and validated a model to predict cesarean for low-risk Chinese…”
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Validation of three models (Tolcher, Levine, and Burke) for predicting term cesarean section in Chinese population by Sun, Fangcan, Shen, Minhong, Han, Bing, Chen, Youguo, Wu, Fangfang

“…Background: Some models predicting cesarean section (CS) have been proposed, with Tolcher, Levine, and Burke model well acknowledged. Tolcher model targets…”
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Shorter Anogenital Distance in Women with Ovarian Endometriomas and Adenomyosis, but Not Uterine Leiomyomas by Liu, Xishi, Ding, Ding, Shen, Minhong, Yan, Dingmin, Guo, Sun-Wei

“…We investigated whether anogenital distance (AGD) is associated with adenomyosis, endometriosis and uterine leiomyomas (UL, also called uterine fibroids). We…”
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Structural Insights into the Tumor-Promoting Function of the MTDH-SND1 Complex by Guo, Feng, Wan, Liling, Zheng, Aiping, Stanevich, Vitali, Wei, Yong, Satyshur, Kenneth A., Shen, Minhong, Lee, Woojong, Kang, Yibin, Xing, Yongna

“…Metadherin (MTDH) and Staphylococcal nuclease domain containing 1 (SND1) are overexpressed and interact in diverse cancer types. The structural mechanism of…”
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Inhibition of cytokinesis by overexpression of NudCL that is localized to the centrosome and midbody by Cai, Yuqi, Yang, Yuehong, Shen, Minhong, Zhou, Tianhua

“…Cytokinesis is the process by which a single cell divides into two physically distinct daughter cells; however, the molecular details of this fundamental…”
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Stresses in the metastatic cascade: molecular mechanisms and therapeutic opportunities by Shen, Minhong, Kang, Yibin

“…Metastasis is the ultimate "survival of the fittest" test for cancer cells, as only a small fraction of disseminated tumor cells can overcome the numerous…”
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Microtubule-binding protein FOR20 promotes microtubule depolymerization and cell migration by Feng, Sijie, Song, Yinlong, Shen, Minhong, Xie, Shanshan, Li, Wenjing, Lu, Yi, Yang, Yuehong, Ou, Guangshuo, Zhou, Jun, Wang, Fudi, Liu, Wei, Yan, Xiaoyi, Liang, Xin, Zhou, Tianhua

“…Microtubules are highly dynamic filaments assembled from αβ-tubulin heterodimers and play important roles in many cellular processes, including cell division…”
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Validation of Six Predictive Models for Adverse Outcomes of Hypertensive Disorders of Pregnancy in Eastern and Western China by SUN Fangcan, HAN Bing, GAO Yan, SHEN Minhong, CHEN Youguo, ZHONG Wen

“…Objective  To explore the application value of six prediction models reported at home and abroad for adverse outcomes of hypertensive disorders of…”
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Role Reversal: A Pro-metastatic Function of E-Cadherin by Shen, Minhong, Kang, Yibin

“…Carcinoma cells often acquire mobility and invasiveness by undergoing epithelial-to-mesenchymal transition, and yet most metastatic lesions remain epithelial…”
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pSTAT3+ Reactive Astrocytes Promote Brain Metastasis by Shen, Minhong, Kang, Yibin

“…The tumor microenvironment contains heterogeneous populations of stromal cells with important roles in cancer progression and metastasis. In a recent study…”
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Cancer fitness genes: emerging therapeutic targets for metastasis by Shen, Minhong, Kang, Yibin

“…Development of cancer therapeutics has traditionally focused on targeting driver oncogenes. Such an approach is limited by toxicity to normal tissues and…”
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