Search Results - "Shen, Michael J"

Differentiation of human and murine induced pluripotent stem cells to microglia-like cells by Pandya, Hetal, Shen, Michael J, Ichikawa, David M, Sedlock, Andrea B, Choi, Yong, Johnson, Kory R, Kim, Gloria, Brown, Mason A, Elkahloun, Abdel G, Maric, Dragan, Sweeney, Colin L, Gossa, Selamawit, Malech, Harry L, McGavern, Dorian B, Park, John K

“…Pandya et al . describe a protocol to differentiate human and mouse iPSCs into cells with the phenotype, transcriptional profile and functional properties of…”
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Heterozygous diploid and interspecies SCRaMbLEing by Shen, Michael J., Wu, Yi, Yang, Kun, Li, Yunxiang, Xu, Hui, Zhang, Haoran, Li, Bing-Zhi, Li, Xia, Xiao, Wen-Hai, Zhou, Xiao, Mitchell, Leslie A., Bader, Joel S., Yuan, Yingjin, Boeke, Jef D.

“…SCRaMbLE (Synthetic Chromosome Rearrangement and Modification by LoxP-mediated Evolution) is a genome restructuring technique that can be used in synthetic…”
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macroH2A1 drives nucleosome dephasing and genome instability in histone humanized yeast by Haase, Max A.B., Lazar-Stefanita, Luciana, Ólafsson, Guðjón, Wudzinska, Aleksandra, Shen, Michael J., Truong, David M., Boeke, Jef D.

“…In addition to replicative histones, eukaryotic genomes encode a repertoire of non-replicative variant histones, providing additional layers of structural and…”
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Resurrecting essential amino acid biosynthesis in mammalian cells by Trolle, Julie, McBee, Ross M, Kaufman, Andrew, Pinglay, Sudarshan, Berger, Henri, German, Sergei, Liu, Liyuan, Shen, Michael J, Guo, Xinyi, Martin, J Andrew, Pacold, Michael E, Jones, Drew R, Boeke, Jef D, Wang, Harris H

“…Major genomic deletions in independent eukaryotic lineages have led to repeated ancestral loss of biosynthesis pathways for nine of the twenty canonical amino…”
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Fecal microbiota transplantation: Uses, questions, and ethics by Grigoryan, Zoya, Shen, Michael J., Twardus, Shaina W., Beuttler, Marc M., Chen, Lea Ann, Bateman-House, Alison

“…Fecal microbiota transplantation (FMT) has rapidly grown in notoriety and popularity worldwide as a treatment for both recurrent and refractory C. difficile…”
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Residual tumor volume and patient survival following reoperation for recurrent glioblastoma by Yong, Raymund L, Wu, Tianxia, Mihatov, Nino, Shen, Michael J, Brown, M Anthony, Zaghloul, Kareem A, Park, Grace E, Park, John K

“…Maximal safe tumor resection is part of the standard of care for patients with newly diagnosed glioblastoma. The role of reoperation in the care of patients…”
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Endosomolytic Anionic Polymer for the Cytoplasmic Delivery of siRNAs in Localized In Vivo Applications by Khormaee, Sariah, Choi, Yong, Shen, Michael J., Xu, Biying, Wu, Haitao, Griffiths, Gary L., Chen, Rongjun, Slater, Nigel K. H., Park, John K.

“…The use of small interfering RNAs (siRNAs) to down‐regulate the expression of disease‐associated proteins carries significant promise for the treatment of a…”
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A Multireporter Bacterial 2‑Hybrid Assay for the High-Throughput and Dynamic Assay of PDZ Domain–Peptide Interactions by Ichikawa, David M, Corbi-Verge, Carles, Shen, Michael J, Snider, Jamie, Wong, Victoria, Stagljar, Igor, Kim, Philip M, Noyes, Marcus B

“…The accurate determination of protein–protein interactions has been an important focus of molecular biology toward which much progress has been made due to the…”
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Treatment resistance mechanisms of malignant glioma tumor stem cells by Schmalz, Philip G R, Shen, Michael J, Park, John K

“…Malignant gliomas are highly lethal because of their resistance to conventional treatments. Recent evidence suggests that a minor subpopulation of cells with…”
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Abstract 5029: Microglia differentiated from induced pluripotent stem cells treat glioma tumors in mice by Pandya, Hetal, Ichikawa, David M., Shen, Michael J., Sedlock, Andrea B., Johnson, Kory R., Maric, Dragan, McGavern, Dorian B., Malech, Harry L., Park, John K.

“…Abstract Glioblastoma Multiforme (GBM), a grade IV astrocytoma is the most aggressive primary brain tumor. GBM patients have the worst prognoses with median…”
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Residual tumor volume and patient survival following reoperation for recurrent glioblastoma: Clinical article by Yong, Raymund L., Wu, Tianxia, Mihatov, Nino, Shen, Michael J., Brown, M. Anthony, Zaghloul, Kareem A., Park, Grace E., Park, John K.

“…Object Maximal safe tumor resection is part of the standard of care for patients with newly diagnosed glioblastoma. The role of reoperation in the care of…”
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